A5101715730- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Allergic Rhinitis and Sensitization
- Indoor Air Quality and Microbial Exposure
- Medical and Biological Ozone Research
- Noise Effects and Management
- Heavy Metal Exposure and Toxicity
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Heme Oxygenase-1 and Carbon Monoxide
- Global Health Care Issues
- Energy and Environment Impacts
- Gut microbiota and health
- Diet and metabolism studies
- Occupational and environmental lung diseases
- Genomics, phytochemicals, and oxidative stress
- Nanoparticles: synthesis and applications
- COVID-19 impact on air quality
- Glutathione Transferases and Polymorphisms
- Asthma and respiratory diseases
- Cancer Research and Treatments
- Metaheuristic Optimization Algorithms Research
- Anomaly Detection Techniques and Applications
- Air Quality Monitoring and Forecasting
- Healthcare professionals’ stress and burnout
- Advanced Malware Detection Techniques
Xinxiang Medical University
2016-2025
The Central Hospital of Shaoyang
2023-2024
Henan Normal University
2024
Lanzhou University
2011-2014
Yuxi Normal University
2013-2014
AntiCancer (United States)
1996
Burnout is a health problem in nurses. Individuals with certain personality are more susceptible to job-related burnout. General self-efficacy (GSE) an important predictor of The relationships between general self-efficacy, burnout and different types still not clear. This study aims analyze the burnout, stress, types, as well their interactions A cross-sectional survey 860 nurses was conducted June July 2015 China. We measured using scale Maslach Occupational Scale, personality, GSE....
Retinal fundus photography provides a non-invasive approach for identifying early microcirculatory alterations of chronic diseases prior to the onset overt clinical complications. Here, we developed neural network models predict hypertension, hyperglycemia, dyslipidemia, and range risk factors from retinal images obtained cross-sectional study in rural areas Xinxiang County, Henan, central China. 1222 high-quality over 50 measurements anthropometry biochemical parameters were generated 625...
Metabolic associated fatty liver disease (MAFLD) is recognized as the component of metabolic syndrome, which mainly related to insulin resistance and genetic susceptibility. It most prevalent chronic worldwide. With rapid lifestyle transitions, its prevalence worldwide increasing, tremendous challenges in controlling this pandemic are arising. The objective study was investigate risk factors MAFLD rural areas Xinxiang, Henan 2017. We conducted a cross-sectional analysis inhabitants aged...
This study aimed to investigate the prevalence of work-related musculoskeletal disorders (WMSD) in nurses, and explore association work style physical exercise with WMSD this professional group.In study, a cross-sectional survey design was applied. A questionnaire conducted on 692 nurses 5 municipal hospitals, period August-October 2015. The included personal information, lifestyle, symptoms WMSD. Chi2 test logistic regression were used identify risk factors WMSD.The 84% all parts body...
Context and objective: Epigallocatechin-3-gallat (EGCG), the major catechin in green tea, shows a potential protective effect against heavy metal toxicity to humans. Apoptosis is one of key events cadmium (Cd2+)-induced cytotoxicity. Nevertheless, study EGCG on Cd2+-induced apoptosis rarely reported. The objective this was clarify detailed mechanism apoptosis.Methods: Normal human liver cells (HL-7702) were treated with Cd2+ for 21 h, then co-treated 3 h. Cell viability, apoptosis,...
Human gut microbiota can be affected by a variety of factors, including geography. This study aimed to clarify the regional specific characteristics in rural residents Xinxiang county, Henan province, with hypertension and hyperlipidemia evaluate association clinical indices. To identify microbes, 16S rRNA gene sequencing was used random forest disease classifier constructed discriminate between hypertension, hyperlipidemia, healthy control. Patients presented marked dysbiosis compared The...
Exposure to ambient PM2.5 is associated with neurodegenerative disorders, in which microglia activation plays a critical role. Thus far, the underlying mechanisms for PM2.5-induced have not been well elucidated. In this study, human microglial cell line (HMC3) was used as vitro model examine inflammatory effect (hall marker of activation) and regulatory pathways. The expression mediators including interleukin-6 (IL-6) cyclooxygenase-2 (COX-2) brain derived neurotrophic factor (BDNF) were...
This study examined the effects of hot high-fat simulants on physicochemical properties microplastics (MPs) from polypropylene (PP)-, low-density polyethylene (LDPE)-, and polylactic acid (PLA)-based single-use food container (SUFC) leachates those aging their immunomodulatory effectors. Scenario studies have demonstrated that MPs were released these three types SUFCs. LDPE- PLA-based SUFCs also cellulose. Among SUFCs, only PP particles exhibited a new absorption peak at 1725 cm-1, which...
Numerous studies have demonstrated a positive correlation between the frequency and severity of allergic rhinitis (AR) with fine particulate matter (PM2.5) exposure, although exact mechanisms remain poorly understood. This study aimed to investigate role gut microbiota disorder NLRP3 pathway activation in PM2.5-induced nasal epithelial barrier damage AR mice. The results indicated that PM2.5 could exacerbate symptoms mucosa. pathway-related proteins including NLRP3, Caspase-1, GSDMD, IL-1β...
Exposure to fine particulate matter (PM2.5) has been associated with respiratory morbidity and mortality. Identification of interventional measures that are efficacious against PM2.5-induced toxicity may provide public health benefits. This study examined the inhibitory effects nutritional supplementation fish oil as a source omega-3 fatty acids vitamin E (Vit E) on lung in rats. Sixty four male Sprague Dawley rats were gavaged phosphate buffered saline (PBS), corn (5 ml/kg), (150 mg/kg), or...
The evidence that exposure to ambient ozone (O3) causes acute cardiovascular effects appears inconsistent. A repeated-measure study with 61 healthy young volunteers was conducted in Xinxiang, Central China. Real-time concentrations of O3 were monitored. Cardiovascular outcomes including blood pressure (BP), heart rate (HR), serum levels high sensitivity C-reactive protein (hs-CRP), 8-hydroxy-2'-deoxyguanosine (8-OHdG), tissue-type plasminogen activator (t-PA), and platelet-monocyte...
The incidence of nasal allergy/allergic rhinitis (AR) is rising worldwide, which has become a serious public health problem. Epidemiological studies point that exposure to environmental PM
Exposure to ambient air-borne fine particulate matter (PM2.5) increases respiratory morbidity and mortality. The mechanisms underlying PM2.5-induced adverse effects remain unclear. This study aimed uncover the molecular of lung toxicity using a mouse model. Scanning electron microscopy inductively coupled plasma mass spectrometry were used examine analyze PM2.5 morphology element compositions, respectively. Twenty four male mice randomly divided into three groups: control (PBS), (4.0 mg/kg...
Exposure to fine particulate matter (PM2.5) is associated with various adverse health effects, such as respiratory and cardiovascular diseases. This study aimed evaluate the association of PM2.5 neural damage biomarkers. A total 34 healthy retirees were recruited from Xinxiang Medical University December 2018 April 2019. Concentrations constituents including 24 metals nonmetallic elements 6 ions, 5 biomarkers brain-derived neurotrophic factor (BDNF), neurofilament light chain (NfL),...
PM2.5 (particulate matter ≤2.5 μm in aerodynamic diameter) is a major urban air pollutant worldwide. Its effects on the respiratory system of susceptible population have been less characterized. This study aimed to estimate association short-term exposure with outcomes retired adults, and examine whether these associations were stronger among subjects GSTT-null genotype. 32 healthy (55–77 years) recruited for five follow-up examinations. Ambient concentrations monitored consecutively 7 days...
Epidemiological evidence has linked air pollution with adverse respiratory outcomes, but the mechanisms underlying susceptibility to remain unclear. This study aimed investigate role of glutathione S-transferase (GST) polymorphism in association between and lung function levels. A total 75 healthy young volunteers aged 18-20 years old were recruited for six follow-up visits examinations. Spirometry was conducted obtain parameters such as forced vital capacity (FVC), expiratory volume 1 s...
Exposure to particulate matter (PM) has been associated with increased hospital admissions for influenza. Airway epithelial cells are a primary target inhaled environmental insults including fine PM (PM2.5) and influenza viruses. The potentiation of PM2.5 exposure on the effects virus airway not adequately elucidated. In this study, (H3N2) infection downstream modulation inflammation antiviral immune response were investigated using human bronchial cell line, BEAS-2B. results showed that...