A5014709725- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Aquaculture disease management and microbiota
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Fish Biology and Ecology Studies
- Aquaculture Nutrition and Growth
- Chromosomal and Genetic Variations
- Microbial Community Ecology and Physiology
- Animal Genetics and Reproduction
- Aquatic Invertebrate Ecology and Behavior
- Methane Hydrates and Related Phenomena
- MicroRNA in disease regulation
- Invertebrate Immune Response Mechanisms
- Identification and Quantification in Food
- Cancer-related molecular mechanisms research
- Physiological and biochemical adaptations
- Lung Cancer Diagnosis and Treatment
- Marine Biology and Ecology Research
- RNA and protein synthesis mechanisms
- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- COVID-19 diagnosis using AI
- Genomic variations and chromosomal abnormalities
- Complement system in diseases
First Affiliated Hospital of Xinxiang Medical University
2009-2025
Sun Yat-sen University
2017-2024
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2020-2024
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2020-2024
Key Laboratory of Guangdong Province
2021-2023
Air Force Medical University
2012-2023
University of Chinese Academy of Sciences
2023
BGI Group (China)
2021
Dalian Medical University
2020
Chongqing Medical University
2020
Abstract The ordering and orientation of genomic scaffolds to reconstruct chromosomes is an essential step during de novo genome assembly. Because this process utilizes various mapping techniques that each provides independent line evidence, a combination multiple maps can improve the accuracy resulting chromosomal assemblies. We present ALLMAPS, method capable computing scaffold maximizes colinearity across collection maps. ALLMAPS robust against common errors, generates sequences are...
Abstract Catfish represent 12% of teleost or 6.3% all vertebrate species, and are enormous economic value. Here we report a high-quality reference genome sequence channel catfish ( Ictalurus punctatus ), the major aquaculture species in US. The was validated by genetic mapping 54,000 SNPs, annotated with 26,661 predicted protein-coding genes. Through comparative analysis genomes transcriptomes scaled scaleless fish scale regeneration experiments, address genomic basis for most striking...
Single nucleotide polymorphisms (SNPs) have become the marker of choice for genome-wide association studies. In order to provide best genome coverage analysis performance and production traits, a large number relatively evenly distributed SNPs are needed. Gene-associated may fulfill these requirements numbers wide distribution. addition, gene-associated could themselves be causative traits. The objective this project was identify using high-throughput next generation sequencing....
Upon the completion of whole genome sequencing, thorough annotation that associates sequences with biological meanings is essential. Genome depends on availability transcript information as well orthology information. In teleost fish, seriously hindered by duplication. Because gene duplications, one cannot establish orthologies simply homology comparisons. Rather intense phylogenetic analysis or structural required for identification genes. To conduct and analysis, full-length transcripts...
The ambient particulate matter pollution may play a critical role in the initiation and development of tracheal, bronchus, lung (TBL) cancer. Up to now, far too little attention has been paid TBL cancer attributable pollution. This study aims assess disease burden global, regional national from 1990 2021 update epidemiology data this disease. Leveraging Global Burden Disease (GBD) study, we analyzed worldwide resulting using indices including disability-adjusted life years (DALYs),...
Abstract Background Gene duplication has had a major impact on genome evolution. Localized (or tandem) resulting from unequal crossing over and whole are believed to be the two dominant mechanisms contributing vertebrate While much scrutiny been directed toward discerning patterns indicative of whole-genome events in teleost species, less attention paid continuous nature gene duplications their size, content, functional diversity, overall architecture genomes. Results Here, using Markov...
Through the Community Sequencing Program, a catfish EST sequencing project was carried out through collaboration between research community and Department of Energy's Joint Genome Institute. Prior to this project, only limited resource from available for purpose SNP identification.A total 438,321 quality ESTs were generated 8 channel (Ictalurus punctatus) 4 blue furcatus) libraries, bringing number nearly 500,000. Assembly all resulted in 45,306 contigs 66,272 singletons. Over 35% unique...
As the global market for fisheries and aquaculture products expands, mislabeling of these has become a growing concern in food safety arena. Molecular species identification techniques hold potential rapid, accurate assessment proper labeling. Here we developed evaluated DNA barcodes use differentiating United States domestic imported catfish species. First, sequenced 651 base-pair from cytochrome oxidase I (COI) gene individuals 9 (and an Ictalurid hybrid) accordance with standard barcoding...
Increasing utilization of stabilized iron sulfides (FeS) nanoparticles implies an elevated release the materials into environment. To understand potential impacts and underlying mechanisms nanoparticle-induced stress, we used transcriptome sequencing (RNA-seq) technique to characterize transcriptomes from adult zebrafish exposed 10 mg/L carboxymethyl cellulose (CMC) FeS for 96 h, demonstrating striking differences in gene expression profiles liver. The exposure caused significant alterations...
Yellow catfish (Pelteobagrus fulvidraco) has been recognized as a vital freshwater aquaculture species in East and Southeast Asia. In addition to its commercial interest, it is also attracted much attention because of value studying sex-determination mechanisms. A comprehensive gonadal transcriptome analysis believed provide resource for genome annotation, candidate gene identification, molecular marker development. Herein, we performed de novo assembly yellow gonad by high-throughput...
Abstract Construction of high-density genetic linkage maps is crucially important for quantitative trait loci (QTL) studies, and they are more useful when integrated with physical maps. Such valuable genome resources fine mapping QTL, comparative genomics, accurate efficient whole-genome assembly. Previously, we established both a map channel catfish, Ictalurus punctatus, the dominant aquaculture species in United States. Here added 2030 BAC end sequence (BES)-derived microsatellites from...
Stachyose is the main transporting sugar in phloem of Raffinose family oligosaccharides-transporting species. synthase (STS) a key enzyme for stachyose biosynthesis, but gene encoding STS poorly characterized cucumber (Cucumis sativus L.), which model plant studying metabolism and function. In this research, (CsSTS) from was isolated its physiological functions were analyzed. CsSTS expressed mainly minor veins mature leaves localized to companion cells. Reverse genetics with RNAi lines...
Sampling challenges in deep-sea ecosystems lead to a lack of knowledge about the distribution microbes different submarine canyons. To study microbial diversity and community turnover under ecological processes, we performed 16S/18S rRNA gene amplicon sequencing for sediment samples from canyon South China Sea. Bacteria, archaea, eukaryotes made up 57.94% (62 phyla), 41.04% (12 1.02% (4 phyla) sequences, respectively. Thaumarchaeota, Planctomycetota,