A5000970882- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Prenatal Screening and Diagnostics
- COVID-19 Clinical Research Studies
- Acute Lymphoblastic Leukemia research
- COVID-19 Impact on Reproduction
- Heparin-Induced Thrombocytopenia and Thrombosis
- Congenital Diaphragmatic Hernia Studies
- Healthcare Systems and Challenges
- Platelet Disorders and Treatments
- Tuberous Sclerosis Complex Research
- Kawasaki Disease and Coronary Complications
- COVID-19 and healthcare impacts
- Myasthenia Gravis and Thymoma
- Vascular anomalies and interventions
- interferon and immune responses
- Williams Syndrome Research
- Pediatric Urology and Nephrology Studies
- Pediatric Pain Management Techniques
- Blood groups and transfusion
- Vascular Malformations and Hemangiomas
- Urological Disorders and Treatments
- Parvovirus B19 Infection Studies
- Blood Coagulation and Thrombosis Mechanisms
- Adenosine and Purinergic Signaling
Case Western Reserve University
2020-2024
MetroHealth
2021-2024
Western University of Health Sciences
2024
MetroHealth Medical Center
2020-2022
Metro Health Hospital
2021
Cleveland Clinic
2016-2019
Cleveland Clinic Lerner College of Medicine
2017
The Ohio State University
2011
Nationwide Children's Hospital
2011
Children's Hospital of Michigan
2005
Abstract COVID‐19 infection has been a significant contributor to global morbidity and mortality, especially among those patients with chronic diseases. The Centers for Disease Control Prevention have classified sickle cell disease (SCD) as condition that increases the risk of severe illness from infection. A retrospective study was conducted using TRiNetX health research network database identify SCA ( HbSS, Sbeta‐thalassemia zero) who had SARS‐CoV‐2 over 2 years; these were compared...
A 10-year-old female with Williams Syndrome (WS) presented a two-month history of fatigue, weight loss, and bilateral ovarian masses. Histologic, immunophenotypic, cytogenetic studies confirmed the diagnosis Burkitt lymphoma (BL). While there is no established association between two disorders, this third case in literature patient Syndrome.
The COVID-19 virus is highly contagious primarily via aerosol transmission and has a high mortality rate. On March 13, 2020, the United States declared national emergency in response to pandemic. This study aims enumerate effect of pandemic on vaccination rates during lockdown aftermath pediatric patients aged 6weeks-6 years.A retrospective review medical records was performed missed well childcare visits at MetroHealth from 1, 2020 June 30, 2020. sample size 400 children 6 weeks years were...
An increase in the incidence of deep vein thrombosis (DVT) has been reported pediatric patients over past decade. The presence central venous line (CVL) is a major contributing risk factor with conflicting data on relative DVT various types lines. We aimed to assess and identify potential factors for overall different CVL individually. A retrospective chart review placed at Cleveland Clinic Children's from 2011 2016 was conducted. Data collected included demographics, factors,...
Beginning early in childhood, patients with sickle cell disease (SCD) are at risk of life-threatening and debilitating health events. Despite the high morbidity mortality this disease, hematopoietic transplantation (HCT), a curative treatment for SCD, remains underutilized. In literature there is paucity data concerning medical decision maker (MDM) awareness HCT as option SCD. The objective study was to estimate proportion parents/guardians children SCD who aware option, identify demographic...
Sickle cell disease (SCD) is caused by a mutation in the sixth codon of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>-globin gene on chromosome 11, which leads to single amino acid substitution (glutamine valine). Sickle-( δβ ) 0 -thalassemia rare variant sickle (delta-beta thalassemia occurring association with hemoglobin, HbS), sparsely reported literature, and has been associated symptomatology necessitating careful...
Beginning early in childhood, patients with sickle cell disease [SCD; a group of genetic haemoglobin disorders characterized by the or HbS mutation (HBB E7V)] are at risk life-threatening and debilitating health events. Despite high morbidity mortality this disease, haematopoietic transplantation (HCT), curative therapy for SCD, remains underutilized. A variety factors, including limited availability suitable donors, play role trend, but do not fully explain low frequency which is employed....
Objective: A retrospective review of pediatric patients diagnosed with GERD long term follow up to study presenting symptoms, associated conditions, response treatment and need step or down from initial treatment. Design/Methods: Chart was performed on by Esophagogastroduodenoscopy (EGD) biopsy. Duration Histamine receptor antagonists (H2RAS) Proton pump inhibitors (PPIS), for if Rx discontinued assessed. Inclusion Criteria: Children >2 yrs at diagnosis. Exclusion neurologic esophageal...
Propranolol has been the new standard-of-care treatment for infantile hepatic hemangioma (IHH) cases necessitating medical based on a case series in 2008 that reported how propranolol resulted involution of cutaneous 2 patients with heart failure. The mechanism action hemangiomas and IHHs is not well-understood, although research suggests other vascular tumors express high amounts β1 to β3 receptors, thus explains why these are susceptible beta-antagonists. However, there reports adverse...