A5070077642- Palliative Care and End-of-Life Issues
- Patient-Provider Communication in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Hemoglobinopathies and Related Disorders
- Diabetes Treatment and Management
- Patient Dignity and Privacy
- Renal function and acid-base balance
- Iron Metabolism and Disorders
- Chronic Kidney Disease and Diabetes
- Chronic Disease Management Strategies
- Parathyroid Disorders and Treatments
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Renal Diseases and Glomerulopathies
- Geriatric Care and Nursing Homes
- Metabolism, Diabetes, and Cancer
- Fatty Acid Research and Health
- Optimism, Hope, and Well-being
- Renal Transplantation Outcomes and Treatments
- Patient Satisfaction in Healthcare
- Potassium and Related Disorders
- Eicosanoids and Hypertension Pharmacology
- Aging, Elder Care, and Social Issues
- Organ Donation and Transplantation
- Health Promotion and Cardiovascular Prevention
Jesse Brown VA Medical Center
2020-2022
Northwestern University
2018-2022
Northwestern Medicine
2022
Hypertension Institute
2018
Cleveland Clinic
2016
Susquehanna University
2014
Rationale & ObjectiveOlder adults with advanced chronic kidney disease (CKD) face difficult decisions about dialysis initiation. Although shared decision making (SDM) can help align patient preferences and values treatment options, the extent to which older patients CKD experience SDM remains unknown.Study DesignA cross-sectional analysis of surveys examining decisional readiness, options education, care partner support, SDM.Setting ParticipantsAdults aged 70 years or from Boston, Chicago,...
IntroductionAbnormalities in lipid metabolism may contribute to the development and progression of chronic kidney disease (CKD) patients with type 2 diabetes. Fenofibrate induces early reversible reduction estimated glomerular filtration rate (eGFR), but it have protective effects on microvascular complications We hypothesized that randomization fenofibrate versus placebo would be associated beneficial long-term outcomes Action Control Cardiovascular Risk Diabetes (ACCORD) trial...
Background and objectives Type 2 diabetes associated CKD disproportionately affect blacks. It is uncertain if racial disparities in type diabetes-associated are driven by biologic factors that influence propensity to or differences care. Design, setting, participants, & measurements We conducted a post hoc analysis of 1937 black 6372 white participants the Action Control Cardiovascular Risk Diabetes (ACCORD) trial examine associations race with change eGFR risks developing...
Patient-reported outcomes-symptoms, treatment side effects, and health-related quality of life-are important to consider in chronic illness care. The increasing availability health IT collect patient-reported outcomes integrate results within the electronic record provides an unprecedented opportunity support patients' symptom monitoring, shared decision-making, effective use care system.The objectives this study are co-design a dashboard that displays along with other clinical data (eg,...
Elevated levels of deoxycholic acid (DCA) are associated with adverse outcomes and may contribute to vascular calcification in patients chronic kidney disease (CKD). We tested the hypothesis that elevated DCA were increased risks cardiovascular disease, CKD progression, death CKD.Prospective observational cohort study.We included 3,147 Chronic Renal Insufficiency Cohort study participants who had fasting levels. The average age was 59 ± 11 years, 45.3% women, 40.6% African American, mean...
The Revised Illness Perception Questionnaire (IPQ-R) measures individuals' unique perceptions of their illness. While psychometric properties the IPQ-R have been demonstrated in many disease populations, its content validity has not extensively studied non-dialysis chronic kidney (CKD). Unique features CKD (e.g., few symptoms early stages) may impact measurement illness perceptions. purpose this study was to explore a sample patients.
Background Deoxycholic acid (DCA) is a secondary bile that may promote vascular calcification in experimental settings. Higher DCA levels were associated with prevalent coronary artery (CAC) small group of individuals advanced chronic kidney disease. Whether are CAC prevalence, incidence, and progression large diverse population disease stages 2 to 4 unknown. Methods Results In the CRIC (Chronic Renal Insufficiency Cohort) study, we evaluated cross-sectional (n=1057) longitudinal (n=672)...
Introduction Given the burdens of treatment and poor prognosis, older adults with kidney failure would benefit from improved decision making palliative care to clarify goals, address symptoms, reduce unwanted procedures. Best Case/Worst Case (BC/WC) is a communication tool that uses scenario planning support patients’ making. This article describes protocol for multisite, cluster randomised trial test effect training nephrologists use BC/WC on patient receipt care, quality life...
The percentage of adults born low birth weight (LBW) is increasing due to advances in neonatal medicine. Studies a variety model organisms indicate that LBW offspring have global perturbations several physiological systems, making it likely impaired reproductive physiology. Therefore, we hypothesized prenatal food restriction produces would cause female hypothalamic pituitary gonadal (HPG) axis dysfunction as evidenced by differences gonadotropin releasing hormone (GnRH), estrous cyclicity...