- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Healthcare Policy and Management
- Chronic Kidney Disease and Diabetes
- Health Systems, Economic Evaluations, Quality of Life
- Palliative Care and End-of-Life Issues
- Primary Care and Health Outcomes
- Health disparities and outcomes
- Chronic Disease Management Strategies
- Geriatric Care and Nursing Homes
- Organ Transplantation Techniques and Outcomes
- Renal and related cancers
- Global Health Care Issues
- Grief, Bereavement, and Mental Health
- Health Literacy and Information Accessibility
- Renal and Vascular Pathologies
- Healthcare Systems and Reforms
- Mobile Health and mHealth Applications
- Healthcare cost, quality, practices
- Medication Adherence and Compliance
- Religion, Spirituality, and Psychology
- Transplantation: Methods and Outcomes
- Body Composition Measurement Techniques
- Potassium and Related Disorders
University of Chicago
2016-2025
University of Chicago Medical Center
2010-2024
University of Illinois Chicago
2024
Prognos (Switzerland)
2022
Johns Hopkins Medicine
2021
Johns Hopkins University
2021
Institute of Medical Ethics
2017
Oregon Health & Science University
2013-2015
In the United States, incidence of ESRD is 1.5 times higher in men than women, despite men's lower prevalence CKD. Prior studies, limited by inclusion small percentages minorities and other factors, suggested that have more rapid CKD progression, but this finding has been inconsistent.In our prospective investigation sex differences we used data from 3939 adults (1778 women 2161 men) enrolled Chronic Renal Insufficiency Cohort Study, a large, diverse cohort. We evaluated associations between...
The Chronic Renal Insufficiency Cohort (CRIC) Study is an ongoing, multicenter, longitudinal study of nearly 5500 adults with CKD in the United States. Over past 10 years, CRIC has made significant contributions to understanding factors associated progression. This review summarizes findings from studies evaluating risk progression Study, grouped into following six thematic categories: ( 1 ) sociodemographic and economic (sex, race/ethnicity, nephrology care); 2 behavioral (healthy...
The inclusion of race in equations to estimate the glomerular filtration rate (GFR) has become controversial. Alternative that can be used achieve similar accuracy without use are needed.
At a given estimated glomerular filtration rate (eGFR), individuals who are Black have higher rates of mortality and kidney failure with replacement therapy (KFRT) compared those non-Black. Whether the recently adopted eGFR equations without race preserve racial differences in risk KFRT at is unknown.To assess whether cystatin C document populations including non-Black participants.Retrospective individual-level data analysis 62 011 participants from 5 general population 3 chronic disease...
Abstract Chronic kidney disease (CKD) is a progressive loss in function. Early detection of patients who will progress to late-stage CKD paramount importance for patient care. To address this, we develop pipeline process longitudinal electronic heath records (EHRs) and construct recurrent neural network (RNN) models predict progression from stages II/III IV/V. The RNN model generates predictions based on time-series patients, including repeated lab tests other clinical variables. Our...
Abstract Background In the U nited S tates, A frican mericans and whites differ in access to deceased donor renal transplant waitlist. The extent which racial disparities waitlisting between N etwork for O rgan haring ( UNOS ) regions is understudied. Methods US R enal D ata ystem USRDS was linked with census data examine time from dialysis initiation (n = 188 410) African Americans 144 335) using C ox proportional hazards across 11 regions, adjusting potentially confounding individual,...
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Prior studies have found that outpatients are frequently unaware of their chronic kidney disease (CKD). Little is known about CKD awareness in hospitalized patients. We conducted a retrospective study general medicine inpatients with CKD, ascertained through International Classification Diseases, Ninth Revision codes for non–dialysis‐dependent (585.0–585.9) first 20 admission diagnoses (n = 590). Patient defined as correct patient self‐report “kidney problems” was 32%. Of 161 patients...
Background: Despite our knowledge of barriers to the early stages transplant process, we have limited insight into patient-reported prekidney medical evaluation in populations largely at-risk for failure. Methods: One-hundred consecutive adults were enrolled at an urban, Midwestern center. Demographic, clinical, and quality life data collected prior patients visit with a surgeon/nephrologist (evaluation begins). Patient-reported completion using Subjective Barriers Questionnaire 90-days...
Prior work has demonstrated how neighborhood poverty and racial composition impact disparities in access to the deceased donor kidney transplant waitlist, both nationally regionally. We examined association between characteristics time waitlist Chicago, a diverse city with continued segregation.Using data from United States Renal Data System (USRDS) US Census, we investigated dialysis initiation waitlisting for African American white patients Chicago using cause-specific proportional hazards...
Autosomal dominant polycystic kidney disease (ADPKD) occurs at conception and is often diagnosed decades prior to failure. Nephrology care transplantation access should be independent of race ethnicity. However, institutional racism barriers health may affect patient outcomes in ADPKD. We sought ascertain the effect disparities on ADPKD by examining age onset failure preemptive after dialysis initiation.
Background. We examined factors associated with depression and anxiety in a cohort of low-income Baltimore women. Methods. used Pathways to Adulthood data, adults aged 27 33 who were born between 1960 1965. Our outcomes score >4 on the General Health Questionnaire (GHQ-28) across or domains. Linear regression clustered census tract was for multivariate analysis. Results. In multivariable analyses, unmarried women, White those lower self-rated health, younger mothers had higher scores. Only...
Barriers to kidney transplant for African Americans are well documented in the literature. Little information on ownership of and communication technology use such populations has been published.To characterize racial differences related patients.A single-center, cross-sectional survey study.An urban Midwestern center.78 pretransplant patients 177 recipients.The consisted 6 demographic questions, 3 disease-related 9 technology-related questions. Dichotomous (yes/no) Likert-scale items were...
We examined whether dialysis facility characteristics, neighborhood demographics, and region are associated with Centers for Medicare Medicaid Services (CMS) quality measures in order to determine the most important targets intervention.We linked US census data CMS Dialysis Compare File which contains information outcomes all CMS-certified facilities 2007 (n=5616). then used linear logistic regression characterize association between quality--worse than expected patient survival, proportion...