A5026922073- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Liver Disease and Transplantation
- Organ and Tissue Transplantation Research
- Renal and Vascular Pathologies
- Vascular Procedures and Complications
- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Pancreatic function and diabetes
- Neurological Complications and Syndromes
- Metabolism and Genetic Disorders
- Cytomegalovirus and herpesvirus research
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Pregnancy and Medication Impact
- Neurological and metabolic disorders
- Acute Kidney Injury Research
- Herpesvirus Infections and Treatments
- Polyomavirus and related diseases
- Palliative Care and End-of-Life Issues
- Surgical Simulation and Training
- Frailty in Older Adults
- Social Media in Health Education
University of Chicago
2013-2023
Texas Christian University
2023
University of Chicago Medical Center
2013-2022
University of Illinois Chicago
2019-2022
UW Health University Hospital
1998-2015
Oregon Health & Science University
2013-2015
Molecular Biology Consortium
2013
John Wiley & Sons (United States)
2011
American Society of Transplantation
2011
Association of Organ Procurement Organizations
2011
Campath‐1H, an anti‐CD52 monoclonal antibody, was used as induction therapy (40 mg i.v. total dose) in 29 primary human renal transplants, and the patients were maintained on rapamycin monotherapy (levels 8–15 ng/mL) post‐transplant. Campath‐1H profoundly depletes lymphocytes long‐term more transiently B cells monocytes. All are alive well at 3–29 months of follow up. One graft lost because rejection. There have been no systemic infections malignancies. Eight experienced rejection, which...
To determine whether the outcomes of liver transplantation (LTx) from donation after cardiac death (DCD) donors are equivalent to those brain (DBD) donors.Because significant donor organ shortage, more transplant centers using livers recovered DCD donors. However, long-term, single-center limited.From January 1, 1993, July 31, 2002, 553 transplants were performed DBD and 36 Differences in event rates between groups compared with Kaplan-Meier estimates log-rank test. proportion differences...
The standard test for the diagnosis of acute rejection in kidney transplants is renal biopsy. Noninvasive tests would be preferable.
Simultaneous pancreas-kidney transplantation (SPK) is a procedure which frees the diabetic patient with end-stage nephropathy from dialysis and daily insulin injections. The purpose of this study to report long-term outcomes procedure, describe surgical medical complications.The analysis includes 1000 consecutive SPKs performed between 1985 2007. Bladder drainage was used in 390 patients enteric 610 patients. In 362 patients, SPK before initiation dialysis.Patient survival at 1, 10, 20 years...
In March 2022, Kidney Disease: Improving Global Outcomes (KDIGO) held a virtual Controversies Conference to address the important but rarely examined phase during which kidney transplant is failing or has failed. addition discussing definition of allograft, 4 broad areas were considered in context declining functioning graft: prognosis and failure trajectory; immunosuppression strategies; management medical psychological complications, patient factors; choice replacement therapy supportive...
Noninvasive diagnosis and prognostication of acute cellular rejection in the kidney allograft may help realize full benefits transplantation. To investigate whether urine metabolites predict status, we determined levels 749 1516 samples from 241 graft recipients enrolled prospective multicenter Clinical Trials Organ Transplantation-04 study. A metabolite signature ratio 3-sialyllactose to xanthosine biopsy specimen-matched supernatants best discriminated specimens without rejection. For...
Background. Advances in perioperative care and immunosuppression have enabled clinicians to broaden the indications for organ transplantation. Advanced age is no longer considered a contraindication transplantation at most centers. Although short-term studies of elderly liver transplant recipients demonstrated that incidence complications overall patient survival are similar those younger adults, center-specific, long-term data not available. Methods. From August 1984 September 1997, 91...
In Brief Objective: The outcomes of simultaneous pancreas-kidney (SPK) transplantation with donor organs procured from donation after cardiac death (DCD) are compared transplants performed recovered brain (DBD). Summary Background Data: Concerns exist regarding the utilization pancreata obtained DCD donors. While it is known that kidneys will have a higher rate DGF, long-term functional graft survival data for not been reported. Methods: A retrospective review all SPK at single center was...
<h3>Background</h3> Preemptive kidney transplantation (PreKT) before initiation of chronic dialysis has been examined recently with favorable results as the most effective treatment for failure. Given that few these studies are disease specific, present analyses investigated outcomes PreKT by option and diabetes type. <h3>Methods</h3> The impact on posttransplantation mortality graft failure was in 23 238 adults type 1 2 mellitus (DM), receiving either living or deceased donor kidneys...
The aim of the American Journal Transplantation is rapid publication new high quality data in organ and tissue transplantation related sciences.The journal reflects field an agent for advancing it through critical reviews news features, consensus documents guidelines.The directed at scientists clinicians but also those other fields who wish to follow transplantation.The scope international discipline transplantation.This includes donation preservation; injury, repair, inflammation, aging;...
Islet allotransplantation in the United States (US) is facing an imminent demise. Despite nearly three decades of progress field, archaic regulatory framework has stymied US clinical practice. Current regulations do not reflect state-of-the-art or technical practices. In US, islets are considered biologic drugs and "more than minimally manipulated" human cell tissue products (HCT/Ps). contrast, across world, appropriately defined as "minimally manipulated tissue" regulated a drug, which led...
136 Advances in perioperative care and immunosuppression have enabled clinicians to broaden the indications for organ replacement therapy. Advanced age is no longer considered a contraindication transplantation at most centers. Although short-term studies of elderly liver recipients demonstrated that incidence complications overall patient survival are similar those younger adults, long-term data not available. From September 1986 1997, 91 patients 60 years or older received primary...
Vascular access complications, including thrombosis, are associated with significant patient morbidity and mortality. Currently, up to 60% of new patients 30% prevalent using a catheter for dialysis. To prevent interdialytic these devices routinely locked concentrated heparin solutions. Several recent studies have elucidated the potential abnormal coagulation markers (aPTT) that may arise from this practice. This elevation in aPTT be explained by early late leakage occurs after performing...
While endovascular stent placement is the standard of care in most percutaneous coronary and peripheral artery intervention, its role salvage thrombosed stenotic hemodialysis access remains controversial.We compared effects versus angioplasty on primary patency rates treatment arteriovenous fistulae (AVF) grafts (AVGs). Moreover, we flow (Qa) urea reduction ratio (URR) between two groups as a metric effect dialysis delivery.Cox regression analysis revealed that assisted AVG was significantly...
Abstract Arteriovenous fistulae (AVF) are widely regarded as the preferred vascular access in hemodialysis patients due to their primary patency and patient survival benefits. While obesity paradox has been associated with improved cardiovascular morbidity all‐cause mortality dialysis patients, its long‐term outcomes less clear. Recent literature suggested that obese may have increased early late fistula failure. The purpose of this study was explore relationships between outcomes. We...