- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
- Sodium Intake and Health
- Nutritional Studies and Diet
- Health disparities and outcomes
- Chronic Kidney Disease and Diabetes
- Diet and metabolism studies
- Food Security and Health in Diverse Populations
- Cardiac Health and Mental Health
- Hormonal Regulation and Hypertension
- Dialysis and Renal Disease Management
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Renin-Angiotensin System Studies
- Global Public Health Policies and Epidemiology
- Health Policy Implementation Science
- Health and Lifestyle Studies
- Cardiovascular Disease and Adiposity
- Health and Wellbeing Research
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Potassium and Related Disorders
- Metabolism, Diabetes, and Cancer
Tulane University
2015-2024
University of New Orleans
2021
Katherine Hospital
2012-2019
Johns Hopkins University
2015-2017
Nanjing Medical University
2017
First Affiliated Hospital of Xiamen University
2017
University College Cork
2015-2016
Kaiser Permanente
2015-2016
University of Alabama
2016
National Heart Lung and Blood Institute
2016
Hypertension is the leading preventable cause of premature death worldwide. We examined global disparities hypertension prevalence, awareness, treatment, and control in 2010 compared secular changes from 2000 to 2010.We searched MEDLINE 1995 through 2014 supplemented with manual searches retrieved article references. included 135 population-based studies 968 419 adults 90 countries. Sex- age-specific prevalences each country were applied population data calculate regional numbers...
Background Hypertension is a major risk factor for cardiovascular disease and all‐cause mortality. Compared with prior guidelines, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline recommends lower blood pressure thresholds defining hypertension, initiating antihypertensive medication, medication treatment goals. Methods Results To better understand potential impacts guideline, we studied trends in mean systolic diastolic , prevalence burden...
<h3>Importance</h3> Patients with chronic kidney disease (CKD) are at an increased risk of cardiovascular (CVD) compared the general population. Prior studies have produced contradictory results on association dietary sodium intake CVD, and this relationship has not been investigated in patients CKD. <h3>Objective</h3> To evaluate between urinary excretion clinical CVD events among <h3>Design, Setting, Participants</h3> A prospective cohort study CKD from 7 locations United States enrolled...
CKD is a major risk factor for ESRD, cardiovascular disease, and premature death. Whether dietary sodium potassium intake affect progression remains unclear. We prospectively studied the association of urinary excretion with all-cause mortality among 3939 patients in Chronic Renal Insufficiency Cohort Study. Urinary were measured using three 24-hour urine specimens, was defined as incident ESRD or halving eGFR. During follow-up, 939 events 540 deaths occurred. Compared lowest quartile...
<h3>Importance</h3> Despite extensive knowledge of hypertension treatment, the prevalence uncontrolled is high and increasing in low- middle-income countries. <h3>Objective</h3> To test whether a community health worker–led multicomponent intervention would improve blood pressure (BP) control among low-income patients with hypertension. <h3>Design, Setting, Participants</h3> A cluster randomized trial was conducted 18 centers for primary care within national public system providing free...
BackgroundRacial and ethnic disparities in mortality persist the US population. We studied contribution of social determinants health (SDoH) to racial premature death.MethodsA nationally representative sample individuals aged 20–74 years who participated National Health Nutrition Examination Survey (NHANES) between 1999 2018 were included. Self-reported SDoH (employment, family income, food security, education, access care, insurance, housing instability, being married or living with a...
Export Background and objectives Previous studies suggest that tobacco, alcohol, illicit drug use is associated with CKD. We examined the associations of substance CKD progression all-cause mortality among patients Design, setting, participants, & measurements The Chronic Renal Insufficiency Cohort Study a prospective, longitudinal cohort study 3939 participants in United States. Self-reported tobacco smoking, alcohol drinking, marijuana use, hard (cocaine, heroin, or methamphetamine) were...
The inclusion of race in equations to estimate the glomerular filtration rate (GFR) has become controversial. Alternative that can be used achieve similar accuracy without use are needed.
<h3>Importance</h3> The 2017 American College of Cardiology/American Heart Association hypertension guideline recommends lower blood pressure (BP) thresholds for initiating antihypertensive medication and treatment goals than the 2014 evidence-based guideline. <h3>Objective</h3> To estimate potential association guidelines with proportion US adults defined as being hypertensive or recommended risk reduction major cardiovascular disease (CVD) all-cause mortality. <h3>Design, Setting,...
Background: Cardiovascular disease (CVD) mortality is persistently higher in the Black population than other racial and ethnic groups United States. Objective: To examine degree to which social, behavioral, metabolic risk factors are associated with CVD extent differences persist after these accounted for. Design: Prospective cohort study. Setting: NHANES (National Health Nutrition Examination Survey) 1999 2018. Participants: A nationally representative sample of 50 808 persons aged 20 years...
Low-carbohydrate diets decrease hemoglobin A1c (HbA1c) among patients with type 2 diabetes at least as much low-fat diets. However, evidence on the effects of low-carbohydrate HbA1c individuals in range prediabetes to not treated by medications is limited.To study effect a behavioral intervention promoting diet compared usual 6-month changes elevated untreated HbA1c.This randomized clinical trial parallel groups was conducted from September 2018 June 2021 an academic medical center New...
The effect of intrarenal renin–angiotensin system (RAS) activity on risk chronic kidney disease (CKD) has not been well studied in human subjects. We investigated the association between urinary angiotensinogen, a reliable biomarker RAS activity, and CKD 201 patients controls. was defined as estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 or presence albuminuria ( ≥ 30 mg/24 h). Compared to controls, median angiotensinogen excretion (45.4 versus 7.4 μg/24 h, P 0.0001)...