A5082485276- Mindfulness and Compassion Interventions
- Dementia and Cognitive Impairment Research
- Family Caregiving in Mental Illness
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
- Digital Mental Health Interventions
- Tryptophan and brain disorders
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Mental Health Treatment and Access
- Stress Responses and Cortisol
- COVID-19 and Mental Health
- Neurological disorders and treatments
- Technology Use by Older Adults
- Resilience and Mental Health
- Geriatric Care and Nursing Homes
- Grief, Bereavement, and Mental Health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Grit, Self-Efficacy, and Motivation
- Health, psychology, and well-being
- Anesthesia and Neurotoxicity Research
- Mobile Health and mHealth Applications
- Behavioral Health and Interventions
- Heart Rate Variability and Autonomic Control
- Asthma and respiratory diseases
Massachusetts General Hospital
2003-2025
Harvard University
2004-2025
Massachusetts College of Pharmacy and Health Sciences
2025
City College of New York
2025
Harvard–MIT Division of Health Sciences and Technology
2024
Massachusetts Institute of Technology
2024
University of California, San Francisco
2016-2023
University of California, Los Angeles
2013-2015
Connecticut Mental Health Center
2015
Neurobehavioral Systems
2013-2015
Black adults experience depression that is more severe than of their White counterparts, yet they are less likely to receive treatment from a mental health professional. This study aimed examine the relationships between medical mistrust or trust and willingness seek care.
Background There are many prognostic factors for treatment outcome in major depressive disorder (MDD). The predictive power of any single factor, however, is limited. We aimed to develop profiles antidepressant response and remission based upon hierarchical combinations baseline clinical demographic factors. Methods Using data from Level 1 the Sequenced Treatment Alternatives Relieve Depression trial (STAR*D), which 2,876 participants with MDD were treated citalopram, a signal-detection...
Objectives Family dementia caregivers are at high risk of depression and burnout. We assessed the feasibility Central Meditation Imagery Therapy for Caregivers (CMIT‐C), a novel 8‐week group meditation guided imagery therapy program, reporting stress because caregiving responsibilities. Methods Twelve family enrolled in CMIT‐C. Primary outcomes included anxiety, secondary insomnia, quality life, mindfulness. Changes over study 3 month follow‐up were analyzed with non‐parametric related...
Family caregivers of patients with dementia suffer a high burden depression and reduced positive emotions. Mentalizing imagery therapy (MIT) provides mindfulness guided skills training to improve balanced mentalizing emotion regulation.
Background: Olfactory dysfunction is one of the earliest signs Alzheimer’s disease (AD), highlighting its potential use as a biomarker for early detection. It has also been linked to progression from mild cognitive impairment (MCI) dementia. Objective: To study olfactory function and associations with markers AD brain pathology in non-demented mutation carriers an autosomal dominant (ADAD) non-carrier family members. Methods: We analyzed cross-sectional data 16 Presenilin1 E280A ADAD (mean...
Family caregivers of persons living with dementia often experience increased depression and suicidal ideation (SI). However, the feasibility impact therapies on caregiver SI has remained largely unexplored. Mentalizing imagery therapy (MIT) helps reduce psychological symptoms through mindfulness guided imagery. This pilot study examined participation by in a randomized controlled trial (RCT) MIT versus psychosocial support group (SG), respective SI, depression, secondary outcomes.
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) down-regulates angiotensin-converting enzyme 2, potentially increasing angiotensin II. We hypothesized that losartan compared to usual care decreases mortality and is safe in patients hospitalized with disease 2019 (COVID-19). aimed evaluate the effect of versus on 28-day for COVID-19. Methods Eligibility criteria included adults admitted Exclusion were hypotension, hyperkalemia, kidney injury, use receptor...
Non-pharmacologically induced altered states of consciousness that promote mental health and wellbeing are a growing focus clinical basic research. Previous work has revealed the mood-augmenting, belief-altering, self-transcendent effects aesthetic-chills-inducing audiovisual stimulation. The current study investigated how guided loving kindness meditation (LKM) combined with uplifting, chills-inducing music (henceforth: chills-augmented) affected participants' mood, self-transcendence (ST),...
Smartphones are increasingly used in health research. They provide a continuous connection between participants and researchers to monitor long-term trajectories of large populations at fraction the cost traditional research studies. However, despite potential using smartphones remote research, there is an urgent need develop effective strategies reach, recruit, retain target representative equitable manner.We aimed investigate impact combining different recruitment incentive distribution...
Family caregivers of patients with Alzheimer disease and related dementias (AD ADRD) often experience high stress are at risk for depression. Technologically delivered therapy is attractive AD ADRD because the time demands associated in-person participation.We aimed to study feasibility conduct limited efficacy testing a mobile app intervention delivering mentalizing imagery (MIT) family caregivers.A 4-week trial MIT was conducted assess use investigate changes in depression symptoms, mood,...