A5040841647- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Treatment of Major Depression
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Mental Health Research Topics
- Dementia and Cognitive Impairment Research
- Neural dynamics and brain function
- Electroconvulsive Therapy Studies
- Neurological disorders and treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pain Management and Placebo Effect
- Pain Management and Treatment
- Migraine and Headache Studies
- Advanced MRI Techniques and Applications
- Obsessive-Compulsive Spectrum Disorders
- Psychosomatic Disorders and Their Treatments
- Genetic Neurodegenerative Diseases
- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Tryptophan and brain disorders
- Schizophrenia research and treatment
- Vagus Nerve Stimulation Research
- Intensive Care Unit Cognitive Disorders
- Body Image and Dysmorphia Studies
University of California, Los Angeles
2013-2025
Neurobehavioral Systems
2014-2025
UCLA Health
1993-2024
Olive View-UCLA Medical Center
2022
The University of Texas Southwestern Medical Center
2019
Advanced Imaging Research (United States)
2019
Brain (Germany)
2011-2016
Connecticut Mental Health Center
2015
New Haven Public Schools
2015
Antioch University Los Angeles
2015
About half of outpatients with major depressive disorder also have clinically meaningful levels anxiety. The authors conducted a secondary data analysis to compare antidepressant treatment outcomes for patients anxious and nonanxious depression in Levels 1 2 the STAR*D study.A total 2,876 adult disorder, enrolled from 18 primary 23 psychiatric care sites, received citalopram Level STAR*D. In 2, 1,292 who did not remit or tolerate were randomly assigned either switch sustained-release...
It has been proposed that 50%-75% of the efficacy antidepressant medication represents placebo effect, since many depressed patients improve when treated with either or placebo. This study examined brain function in subjects receiving active and sought to determine whether quantitative electroencephalography (QEEG) could detect differences between responders. Both QEEG power cordance, a new measure reflects cerebral perfusion is sensitive effect medication, were examined.Fifty-one major...
Symptoms of Major Depressive Disorder (MDD) are hypothesized to arise from dysfunction in brain networks linking the limbic system and cortical regions. Alterations functional connectivity resting-state have been detected with imaging techniques, but neurophysiologic measures not systematically examined. We used weighted network analysis examine resting state as measured by quantitative electroencephalographic (qEEG) coherence 121 unmedicated subjects MDD 37 healthy controls. Subjects had...
Preliminary findings support the potential of yoga as a complementary treatment depressed patients who are taking anti-depressant medications but only in partial remission. The purpose this article is to present further data on intervention, focusing individual differences psychological, emotional and biological processes affecting outcome. Twenty-seven women 10 men were enrolled study, whom 17 completed intervention pre- post-intervention assessment data. consisted 20 classes led by senior...
Clinical and neuropathological evaluation of elderly subjects with dementia has traditionally concentrated upon the focal distribution brain disease, ignoring changes in complex connections that link areas are crucial for cognition. We examined two most common forms (dementia Alzheimer type or DAT, multi-infarct MID); used electroencephalographic (EEG) coherence to examine effects these illnesses on functional between areas. studied known be linked by different types connections: (i) dense...
This article uses a general latent variable framework to study series of models for nonignorable missingness due dropout. Nonignorable missing data modeling acknowledges that may depend not only on covariates and observed outcomes at previous time points as with the standard random assumption, but also variables such values would have been (missing outcomes), developmental trends (growth factors), qualitatively different types development (latent trajectory classes). These alternative...
• The accurate diagnosis of dementia is difficult because there are no specific physiologic tests. Computer-analyzed electroencephalography (EEG) has shown promise as a tool for the differential dementia, but topographic methods data collection and analysis have seldom been used. We used these to investigate EEG differences among three groups elderly subjects: those with mild moderate Alzheimer's type (DAT), multiinfarct (MID), age- sex-matched normal controls. two demented subjects were...
HYPOTHESIS AND THEORY article Front. Hum. Neurosci., 26 February 2013Sec. Brain Imaging and Stimulation Volume 7 - 2013 | https://doi.org/10.3389/fnhum.2013.00037
Purpose We conducted a randomized clinical trial evaluating the efficacy of cognitive rehabilitation (CR) intervention compared with wait list (WL) control condition on complaints, neuropsychological and brain functioning in breast cancer survivors (BCS). Methods The small group five sessions included psychoeducation exercises. Eligibility Disease-free BCS diagnosed stage I, II or III cancer, completed primary treatment 18 months to 5 years earlier. Neurocognitive test data complaints...
Abstract Background Repetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown. We explored how concomitant medication use relates clinical response a standard course of rTMS. Methods Medications were tabulated for 181 MDD who underwent six‐week rTMS course. All received 10 Hz left dorsolateral prefrontal cortex (DLPFC), with 1 right DLPFC in...
DEPRESSION in the aging and aged is a major public health problem. It causes suffering to many who go undiagnosed, it burdens families institutions providing care for elderly by disabling those might otherwise be able-bodied. What makes depression so insidious that neither victim nor provider may recognize its symptoms context of multiple physical problems people. Depressed mood, typical signature depression, less prominent than other depressive such as loss appetite, sleeplessness, anergia,...
The placebo response shows pronounced interindividual variability. Placebos are postulated to act through central reward pathways that modulated by monoamines. Because monoaminergic signaling is under strong genetic control, we hypothesized common functional polymorphisms modulating tone would be related degree of improvement during treatment subjects with major depressive disorder. We examined in genes encoding the catabolic enzymes catechol-O-methyltransferase and monoamine oxidase A....
Background Painful physical symptoms (PPS) are both common and reduce the likelihood of remission in major depressive disorder (MDD), based upon results clinical trials selected populations. Whether PPS significantly contribute to poorer treatment outcome overall primary or specialty psychiatric care settings remains unclear. Method Out-patients ( n =2876) with MDD were treated first step Sequenced Treatment Alternatives Relieve Depression (STAR*D) trial citalopram up 60 mg/day for 14 weeks....