A5047802942- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Global Cancer Incidence and Screening
- Patient-Provider Communication in Healthcare
- Healthcare Policy and Management
- Patient Satisfaction in Healthcare
- Economic and Financial Impacts of Cancer
- Palliative Care and End-of-Life Issues
- Cancer-related cognitive impairment studies
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Maternal and fetal healthcare
- Prenatal Screening and Diagnostics
- Family Support in Illness
- Maternal and Perinatal Health Interventions
- Organ Donation and Transplantation
- Grief, Bereavement, and Mental Health
- Reproductive Health and Technologies
- Childhood Cancer Survivors' Quality of Life
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
University of California, Los Angeles
2016-2025
VA Greater Los Angeles Healthcare System
2024
UCLA Health
2016-2024
University of Southern California
2004-2024
UCLA Medical Center
2024
Community Link
2024
Society for Maternal-Fetal Medicine
2024
Institute for Female Pelvic Medicine and Reconstructive Surgery
2021
Stanford University
2021
Ronald Reagan UCLA Medical Center
2019
Background: During the last decade, survival rates for breast cancer have increased as a result of earlier detection and use adjuvant therapy. Limited data exist on psychosocial aspects transitional period between end primary treatment survivorship. We investigated baseline status women enrolled in randomized trial testing two interventions at treatment. Methods: Participants, identified within 1 month after surgery (registration), provided demographic information limited measures quality...
Fatigue, depression, and sleep disturbance are common adverse effects of cancer treatment frequently co-occur. However, the possibility that inflammatory processes may underlie this constellation symptoms has not been examined.Women (N = 103) who had recently finished primary (ie, surgery, radiation, chemotherapy) for early-stage breast completed self-report scales provided blood samples determination plasma levels markers: soluble tumor necrosis factor (TNF) receptor II (sTNF-RII),...
In the current study, authors attempted to describe incidence, most common sites, and mortality of second primary malignancies among survivors cancers.The identified patients aged ≥18 years who were diagnosed with a malignancy from 10 cancer sites (prostate, breast, lung, colon, rectum, bladder, uterus, kidney, melanoma, non-Hodgkin lymphoma) between 1992 2008 Surveillance, Epidemiology, End Results data. Factors associated incidence explored using bivariable multivariable models,...
Purpose The 2000 National Institutes of Health Consensus Conference on Adjuvant Therapy Breast Cancer recommended chemotherapy for all women with invasive cancer greater than 1 centimeter. Studies long-term breast survivors have found poorer quality life (QOL) in who received adjuvant chemotherapy. aim this article is to characterize physical and psychosocial recovery as a function receipt the year after medical treatment completion. Patients Methods Prospective longitudinal survey data...
<h3>Importance</h3> Magnetic resonance imaging (MRI) guidance improves the accuracy of prostate biopsy for detection clinically significant cancer, but optimal use such is not yet clear. <h3>Objective</h3> To determine cancer rate (CDR) targeting MRI-visible lesions vs systematic sampling in diagnosis men who were naive. <h3>Design, Setting, and Participants</h3> This paired cohort trial, known as Prospective Assessment Image Registration Diagnosis Prostate Cancer (PAIREDCAP) study, was...
The primary treatments for clinically localized prostate cancer confer equivalent control most patients but disparate side effects. In the current study, authors sought to compare health-related quality of life (HRQOL) outcomes after commonly used treatments.A total 580 men completed Medical Outcomes Study Short Form-36, University California-Los Angeles (UCLA) Prostate Cancer Index, and American Urological Association Symptom Index before through 24 months treatment with radical...
Purpose Evidence suggests that the re-entry phase (ie, early period after medical treatment completion) presents distinct challenges for cancer patients. To facilitate transition to recovery, we conducted Moving Beyond Cancer (MBC) trial, a multisite, randomized, controlled trial of psychoeducational interventions breast Methods Breast patients were registered within 6 weeks surgery. After treatment, they completed baseline measures and randomly assigned standard National Institute print...
Spirituality is a multidimensional construct, and little known about how its distinct dimensions jointly affect well-being. In longitudinal studies (Study 1, n = 418 breast cancer patients; Study 2, 165 survivors), the authors examined 2 components of spiritual well-being (i.e., meaning/peace faith) their interaction, as well change scores on those variables, predictors psychological adjustment. higher baseline meaning/peace, an increase in over 6 months, predicted decline depressive...
Background: Various groups have called for a national system to monitor the quality of cancer care. The validity registry data care has not been well studied. We investigated such information in California Cancer Registry. Methods: compared associated with abstracted from medical records patients diagnosed breast cancer. also calculated score each subject by determining proportion four evidence-based indicators that were met and then overall scores obtained record data. All statistical tests...
Cognitive complaints are reported frequently after breast cancer treatments. Their association with neuropsychological (NP) test performance is not well-established. Early-stage, posttreatment patients were enrolled in a prospective, longitudinal, cohort study prior to starting endocrine therapy. Evaluation included an NP battery and self-report questionnaires assessing symptoms, including cognitive complaints. Multivariable regression models assessed associations among complaints, mood,...
Decision making for treatment of localized prostate cancer is often guided by therapeutic side-effect profiles. We sought to assess health-related quality-of-life outcomes patients 48 months after cancer. Men treated (N = 475) were evaluated before and at 11 intervals during the intervention. Changes in mean scores probability regaining baseline levels quality life compared between groups. All statistical tests two-sided. Urinary incontinence was more common prostatectomy (n 307) than...
Men with low-risk prostate cancer and significant comorbidity are susceptible to overtreatment. The authors sought compare the impact of age on treatment choice in men disease.The sampled 509 diagnosed at Greater Los Angeles Long Beach Veterans Affairs Medical Centers between 1997 2004. Rates aggressive (radical prostatectomy, radiation therapy, brachytherapy) were determined among different ages Charlson scores. Multivariate modeling was used determine influence both variables predicting...
Purpose We conducted a randomized clinical trial evaluating the efficacy of cognitive rehabilitation (CR) intervention compared with wait list (WL) control condition on complaints, neuropsychological and brain functioning in breast cancer survivors (BCS). Methods The small group five sessions included psychoeducation exercises. Eligibility Disease-free BCS diagnosed stage I, II or III cancer, completed primary treatment 18 months to 5 years earlier. Neurocognitive test data complaints...
Importance Non-Hispanic Black (hereafter, Black) individuals experience worse prostate cancer outcomes due to socioeconomic and racial inequities of access care. Few studies have empirically evaluated these disparities across different health care systems. Objective To describe the ethnic neighborhood status (nSES) among residents same communities who receive in US Department Veterans Affairs (VA) system vs other settings. Design, Setting, Participants This cohort study obtained data from VA...
Abstract Spirituality is interdependent with the biological, psychological, and interpersonal aspects of life. Although spirituality has been studied in breast cancer survivors, little work done men prostate cancer. We sought to determine whether lower early stage associated worse general health‐related quality life (HRQOL), disease‐specific HRQOL, or psychosocial health. Two hundred twenty‐two subjects were drawn from a state‐funded program providing free treatment indigent men. Validated...
Within a framework of quality assessment, primary treatment choice constitutes an indicator care. This study examines geographic and socioeconomic variation in the men with prostate cancer during era prostate-specific antigen testing.Using National Cancer Institute's Surveillance, Epidemiology, End Results public use data files, we identified localized/regional who underwent surgery, radiation therapy, or watchful waiting. We used year 2000 US Census information to ascribe education income...
Abstract BACKGROUND: Accurate estimation of life expectancy is essential for men deciding between aggressive and conservative treatment prostate cancer. The authors sought to assess the competing risks nonprostate cancer mortality among with differing Charlson comorbidity index scores tumor risks. METHODS: conducted a retrospective study 1482 nonmetastatic diagnosed from 1997 2004 at Greater Los Angeles Long Beach Veterans Affairs Medical Centers. They performed Kaplan‐Meier regression...
Bladder cancer is the second most common tobacco-related malignancy. A new bladder diagnosis may be an opportunity to imprint smoking cessation. Little known about impact of a on patterns tobacco use and cessation among patients with incident cancer.A simple random sample noninvasive survivors diagnosed in 2006 was obtained from California Cancer Registry. Respondents completed survey history use, beliefs regarding risk factors, physician influence were compared by status. Those respondents...
Purpose Most malignancies are diagnosed in older adults who potentially susceptible to aging-related health conditions; however, the manifestation of geriatric syndromes during surgical cancer treatment is not well quantified. Accordingly, we sought assess prevalence and ramifications events major surgery for cancer. Patients Methods Using Nationwide Inpatient Sample data from 2009 2011, examined hospital admissions among elderly patients (ie, age ≥ 65 years) a referent group 55 64 years....
Anxiety may serve as a major barrier to participation in active surveillance. Intolerance of uncertainty, that is the tendency perceive potential for negative events threatening, has been linked cancer related worry. Accordingly we explored prospectively relationship intolerance uncertainty with anxiety along other clinical factors among men treated surveillance prostate cancer.A total 119 D'Amico low risk participating completed HADS (Hospital and Depression Scale), MAX-PC (Memorial Scale...