A5068058685- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Child and Adolescent Psychosocial and Emotional Development
- Advanced Causal Inference Techniques
- Mental Health Treatment and Access
- Health disparities and outcomes
- Attention Deficit Hyperactivity Disorder
- Facial Trauma and Fracture Management
- Health Policy Implementation Science
- Bayesian Methods and Mixture Models
- Census and Population Estimation
- Primary Care and Health Outcomes
- Forensic Toxicology and Drug Analysis
- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Statistical Methods in Clinical Trials
- Mental Health and Patient Involvement
- Healthcare Policy and Management
- Child Abuse and Trauma
- Maternal Mental Health During Pregnancy and Postpartum
- Parathyroid Disorders and Treatments
- Survey Methodology and Nonresponse
- Health Systems, Economic Evaluations, Quality of Life
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
University of California, Los Angeles
2015-2024
UCLA Health
2004-2022
Neurobehavioral Systems
1998-2022
Stanford University
2022
Oklahoma State University Center for Health Sciences
2000-2018
Fielding Graduate University
2016-2018
APLA Health
2018
National Institute of Dental and Craniofacial Research
2018
Public Health Dayton & Montgomery County
2018
RAND Corporation
2004-2017
ContextFew depressed older adults receive effective treatment in primary care settings.ObjectiveTo determine the effectiveness of Improving Mood–Promoting Access to Collaborative Treatment (IMPACT) collaborative management program for late-life depression.DesignRandomized controlled trial with recruitment from July 1999 August 2001.SettingEighteen clinics 8 health organizations 5 states.ParticipantsA total 1801 patients aged 60 years or major depression (17%), dysthymic disorder (30%), both...
PURPOSE: To describe the occurrence of fatigue in a large sample breast cancer survivors relative to general population norms and identify demographic, medical, psychosocial characteristics fatigued survivors. PATIENTS AND METHODS: Breast two metropolitan areas completed standardized questionnaires as part survey study, including RAND 36-item Health Survey, Center for Epidemiological Studies–Depression Scale, Cancer Prevention Trial Symptom Checklist, Medical Outcomes Study Sleep demographic...
A longitudinal study was designed to evaluate the prevalence, persistence, and predictors of posttreatment fatigue in breast carcinoma survivors.A sample 763 survivors completed questionnaires at 1-5 5-10 years after diagnosis, including RAND 36-item Health Survey, Center for Epidemiological Studies - Depression scale (CES-D), Breast Cancer Prevention Trial Symptom Checklist, demographic treatment-related measures.Approximately 34% participants reported significant which is consistent with...
Background: During the last decade, survival rates for breast cancer have increased as a result of earlier detection and use adjuvant therapy. Limited data exist on psychosocial aspects transitional period between end primary treatment survivorship. We investigated baseline status women enrolled in randomized trial testing two interventions at treatment. Methods: Participants, identified within 1 month after surgery (registration), provided demographic information limited measures quality...
Abstract Purpose: Biomarkers of radiation-induced behavioral symptoms, such as fatigue, have not been identified. Studies linking inflammatory processes to fatigue in cancer survivors led us test the hypothesis that activation proinflammatory cytokine network is associated with symptoms during radiation therapy for breast and prostate cancer. Experimental Design: Individuals early-stage (n = 28) (n= 20) completed questionnaires provided blood samples determination serum levels interleukin 1β...
Purpose The 2000 National Institutes of Health Consensus Conference on Adjuvant Therapy Breast Cancer recommended chemotherapy for all women with invasive cancer greater than 1 centimeter. Studies long-term breast survivors have found poorer quality life (QOL) in who received adjuvant chemotherapy. aim this article is to characterize physical and psychosocial recovery as a function receipt the year after medical treatment completion. Patients Methods Prospective longitudinal survey data...
PURPOSE: To identify variables that might be predictive of sexual health (interest, dysfunction, and satisfaction) in a large sample breast cancer survivors, with validation conducted second, independent sample. PATIENTS AND METHODS: On the basis conceptual framework we performed multivariable regression analyses to estimate interest, satisfaction both samples. Additional were using stepwise recursive partitioning explore each relative contributions toward predicting outcome measures....
The relationship of various dimensions temperament, measured by the Tridimensional Personality Questionnaire (TPQ), to polymorphisms D2 dopamine receptor (DRD2) and D4 (DRD4) genes was determined in 119 healthy Caucasian boys who had not yet begun consume alcohol other drugs abuse. Total Novelty Seeking score TPQ significantly higher having, common, all three minor (A1, B1, Intron 6 1) alleles DRD2 compared without any these alleles. Boys with DRD4 7 repeat (7R) allele also a than those this...
Abstract The response to cerebral hypoxia/ischemia may be different in the neonate compared other age groups. An vivo model was developed rat determine whether there are age‐dependent differences effects of hypoxia on electroencephalographic (EEG) activity. EEG recordings were obtained from Long Evans hooded rats deprived oxygen at five ages: postnatal days 5 7, 10 12, 15 17, 25 27, and 50 60. Oxygen concentration varied 0,2,3, 4% between animals. EEGs recorded all animals before, during, 1...
Purpose Evidence suggests that the re-entry phase (ie, early period after medical treatment completion) presents distinct challenges for cancer patients. To facilitate transition to recovery, we conducted Moving Beyond Cancer (MBC) trial, a multisite, randomized, controlled trial of psychoeducational interventions breast Methods Breast patients were registered within 6 weeks surgery. After treatment, they completed baseline measures and randomly assigned standard National Institute print...
Cognitive complaints are reported frequently after breast cancer treatments. Their association with neuropsychological (NP) test performance is not well-established. Early-stage, posttreatment patients were enrolled in a prospective, longitudinal, cohort study prior to starting endocrine therapy. Evaluation included an NP battery and self-report questionnaires assessing symptoms, including cognitive complaints. Multivariable regression models assessed associations among complaints, mood,...
Abstract Multiple imputation has become easier to perform with the advent of several software packages that provide imputations under a multivariate normal model, but missing binary data remains an important practical problem. Here, we explore three alternative methods for converting imputed value into value: (1) simple rounding nearer 0 or 1, (2) Bernoulli draw based on ‘coin flip’ where between and 1 is treated as probability drawing (3) adaptive scheme cut‐off determining whether round...
Depression contributes to disability and there are ethnic/racial disparities in access outcomes of care. Quality improvement (QI) programs for depression primary care improve relative usual care, but health, social other community-based service sectors also support clients under-resourced communities. Little is known about effects on client strategies implement QI across diverse sectors.To compare the effectiveness Community Engagement Planning (CEP) Resources Services (RS) clients' mental...
Abstract Specifying a record-linkage procedure requires both (1) method for measuring closeness of agreement between records, typically scalar weight, and (2) rule deciding when to classify records as matches or nonmatches based on the weights. Here we outline general strategy second problem, that is, accurately estimating false-match rates each possible cutoff weight. The uses model where distribution observed weights are viewed mixture true false matches. An EM algorithm fitting mixtures...
OBJECTIVES: Attention deficit hyperactivity disorder (ADHD), a common psychiatric condition, may impair child's ability to learn and form social relationships, tasks critical healthy development. This study describes the prevalence of among children in special education programs identifies extent predictors unmet service needs. METHODS: A 2-stage screening protocol countywide population second- through fourth-grade students was conducted (1) screen for ADHD, employing standardized parent...
Following a suicide attempt by female adolescents, the impact of specialized emergency room (ER) care intervention was evaluated over subsequent 18 months. Using quasi-experimental design, this study assigned 140 adolescent attempters (SA), ages 12-18 years, and their mothers (88% Hispanic) to receive during ER visit either: (a) aimed at enhancing adherence outpatient therapy providing soap opera video regarding suicidality, family session, staff training; or (b) standard care. The...
Patients with inflammatory bowel disease (IBD) have a high prevalence of osteoporosis. A number studies found that corticosteroid use is associated the development osteoporosis in these patients. Calcium supplementation may be benefit corticosteroid-induced and calcium nutrient patients IBD lack.To test on bone density pilot study over 1-year period, group corticosteroid-using IBD, randomized, double-blind, placebo-controlled treatment study.Corticosteroid-using including males age 18 years...
OBJECTIVE: The diagnosis of bipolar disorder in juveniles is controversial. This study was designed to compare proton magnetic resonance spectroscopy (1H MRS) patients with or intermittent explosive disorder, two groups symptomatic overlap but categorical distinction. Children designate whose illness clinically resembles pediatric does not satisfy DSM-IV criteria for mania. Based on the authors' previous report higher levels 1H MRS cingulate myo-inositol/creatine youngsters than normal...