A5087180693- Hormonal Regulation and Hypertension
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Thyroid Disorders and Treatments
- Adrenal Hormones and Disorders
- Neuroendocrine Tumor Research Advances
- Growth Hormone and Insulin-like Growth Factors
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Research Studies
- Vitamin D Research Studies
- Neuroblastoma Research and Treatments
- Clusterin in disease pathology
- Thyroid Cancer Diagnosis and Treatment
- Sexual Differentiation and Disorders
- Fibroblast Growth Factor Research
- Systemic Sclerosis and Related Diseases
- Lipid metabolism and disorders
- Electrolyte and hormonal disorders
- Kruppel-like factors research
- Gestational Trophoblastic Disease Studies
- Biotin and Related Studies
- Hormonal and reproductive studies
- Pregnancy and preeclampsia studies
- Vitamin K Research Studies
- Parathyroid Disorders and Treatments
Postgraduate School of Molecular Medicine
2013-2025
Grochowski Hospital
2012-2023
Provincial Polyclinical Hospital in Toruń
2015
Centrum Medyczne Kształcenia Podyplomowego
2009
The polycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathies in women. Its incidence assessed at 6-8% female population reproductive age. It characterised by oligomenorrhea (Oligo), hyperandrogenism (HA), and presence ovaries (PCOs). Carbohydrate lipid metabolism being disturbed many women with PCOS. pathogenesis PCOS still unexplained. Following main criteria diagnosis (Rotterdam Consensus 2003), Dewailly, Welt Pehlivanov divided patients into 4 phenotype groups: A, B,...
A wide use of imaging techniques results in more frequent diagnosis adrenal incidenataloma.To analyse the current state knowledge on incidentaloma adults order to prepare practical management recommendations.Following a discussion, Polish Society Endocrinology expert working group have analysed available data and summarised analysis form recommendations.Unenhanced computed tomography (CT) may be recommended as an initial assessment examination helpful differentiation between adenomas...
Developmental Index in children at 10 months of age.The relative risk (RR) for impaired psychomotor development was 5.8 (95% CI, 1.3-12.6).Those results were confirmed 2003 by the same team age 1 and 2 years. 3 It also appeared that negative impact maternal early gestation hypothyroxinemia on infant neurodevelopment could be overcome when fT 4 concentration increased during further course pregnancy.From time, a large body literature adverse overt subclinical hypothyroidism (SH) obstetric...
Primary aldosteronism (PA) is estimated to occur in 5–12% of patients with hypertension. Assessment aldosterone / plasma renin activity (PRA) ratio (ARR) has been used as a screening test suspected PA. Direct determination (DRC) and calculation direct concentration (ADRR) could be similarly useful for The study included 62 indication evaluation the renin-angiotensin-aldosterone system 35 healthy volunteers. In all participants we measured concentrations serum aldosterone, renin, PRA after...
Adrenal scintigraphy with 131I-6β-iodomethylnorcholesterol is considered by several authors the gold standard for assessing tumors subclinical hypercortisolemia. However, most of described series consist mainly cases unilateral lesions. The aim our study was to assess whether useful in choosing adrenalectomy side case bilateral adrenal hypercortisolemia.The focused on 15 consecutive patients benign and performed. Fourteen underwent adrenalectomy; gland predominant uptake removed. Cortisol...
Normal 0 21 false PL X-NONE Introduction: Chromogranin A (CgA) is a major, nonspecific marker of neuroendocrine tumours (NET). There are few routinely used assays for the measurement CgA concentration in serum or plasma. These differ analytical techniques (radioimmunoassay, ELISA, CLIA, TRACE), have different calibrators, and use antibodies which recognise epitopes molecule. Our study was designed to confirm noted earlier differences levels measured plasma, establish respective reference...
Levothyroxine (LT4) is a standard therapy in hypothyroidism; however, its bioavailability and therapeutic effects might be affected by many factors. Data shows that with liquid LT4 characterized quicker pharmacokinetics provides better thyroid hormones control than tablet LT4. We addressed the quality of life (QoL) efficacy new ethanol-free formula (Tirosint®SOL) treatment 76 euthyroid patients primary (PH, n = 46) central hypothyroidism (CH, 30), compared results to retrospective data on...
Introduction: Performing measurements of plasma renin activity (PRA) or direct concentration (DRC) and aldosterone concentration, we should be well informed about requirements concerning blood sample processing. Material methods: Forty-seven patients had collected in the supine upright positions. Blood was withdrawn into two EDTA2K tubes one with clot activator. One tube cooled at +4°C centrifuged whereas other prepared room temperature. PRA DRC were measured by radioimmunoassay (RIA)...
According to some authors, a higher incidence of subclinical hypercortisolemia is found among patients with bilateral benign adrenal tumors than in those unilateral tumors. It still unknown whether all and should undergo surgery, and, if so, which tumor be removed first.The aim the study was investigate adrenalectomy can lead resolution improvement their clinical status.The group consisted 25 hypercortisolemia. In 24 patients, performed. The gland selected for removal on basis scintigraphy...
Hyperthyroidism affects approximately 1.2% of the population and its routine treatment includes antithyroid drugs (ATDs), radioiodine surgery. Management patients with resistance or contraindications to ATDs who require thyroidectomy may be challenging. We present experience our department in preparing thyrotoxic for life-saving by using therapeutic plasma exchange (TPE) albumin: one patient Graves' disease previous history agranulocytosis cholestatic jaundice after two amiodarone-induced...
Wstęp: Guzy nadnercza mogą produkować specyficzne hormony i powodować charakterystyczne objawy kliniczne, ale przeważająca część guzów, zwłaszcza typu incydentaloma, jest niema klinicznie, chociaż z nich może mieć charakter złośliwy albo stanowić inne potencjalne zagrożenie dla życia. Chromogranina A (CgA) głównym, niespecyficznym markerem guzów neuroendokrynnych (NET). Jest ona produkowana także między innymi przez komórki chromafinowe rdzenia nadnerczy jej pomiar we krwi mógłby być...
To determine whether a single measurement of ACTH instead less available in daily practice 11-deoxycortisol assay is sufficient to rule out or confirm secondary adrenal insufficiency (SAI) the short Metyrapone test.A retrospective analysis diagnostic tests (Metyrapone and Synacthen tests) performed at our Center between 2016 2018 patients with suspicion insufficiency.In 103 metyrapone test was assessment concentration after administered midnight. In 89 them (SST) also done (1 or/and 250 mcg...
Primary aldosteronism (PA) is the most common, but broadly underdiagnosed, form of hormonal hypertension. To improve screening procedures, current biochemical approaches aim to determine newly appreciated angiotensin II (Ang II) and calculate aldosterone-to-angiotensin ratio (AA2R). Thus, this study was assess diagnostic performance these tests in comparison aldosterone-to-direct renin (ADRR), which routinely used. Cheap available ELISA used for Ang measurement. our knowledge, first...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)