A5085761677- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Memory and Neural Mechanisms
- Neurotransmitter Receptor Influence on Behavior
- Neurological disorders and treatments
- Alzheimer's disease research and treatments
- Trace Elements in Health
- Estrogen and related hormone effects
- Regulation of Appetite and Obesity
- Medicinal Plants and Bioactive Compounds
- Receptor Mechanisms and Signaling
- Olfactory and Sensory Function Studies
- Menopause: Health Impacts and Treatments
- Parkinson's Disease Mechanisms and Treatments
- Pregnancy and preeclampsia studies
- Neuroscience of respiration and sleep
- Anesthesia and Neurotoxicity Research
- Neurogenesis and neuroplasticity mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Sleep and Wakefulness Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Birth, Development, and Health
- Schizophrenia research and treatment
- Ion channel regulation and function
Benemérita Universidad Autónoma de Puebla
2012-2022
Autonomous University of Tlaxcala
2022
Instituto Politécnico Nacional
2011-2014
National Commission for the Knowledge and Use of Biodiversity
2014
ABSTRACT Sleep is a fundamental state necessary for maintenance of physical and neurological homeostasis throughout life. Several studies regarding the functions sleep have been focused on effects deprivation synaptic plasticity at molecular electrophysiological level, only few studied function from structural perspective. Moreover, during normal aging, architecture displays some changes that could affect development in elderly. In this study, using Golgi‐Cox staining followed by Sholl...
Abstract In Alzheimer's disease brains, morphological changes in the dendrites of pyramidal neurons prefrontal cortex (PFC) and hippocampus have been observed. These are particularly reflected decrement both dendritic tree spine number. Donepezil is a potent selective acetylcholinesterase inhibitor used treatment disease. We studied effect oral administration this drug on morphology neuronal cells from brain aged rats. examined PFC, dorsal or ventral (VH), medium spiny nucleus accumbens...
Abstract A neonatal basolateral‐amygdala (nBLA) lesion in rats could be a potential animal model to study the early neurodevelopmental abnormalities associated with behavioral and morphological brain changes observed schizophrenia. Morphological alterations pyramidal neurons from prefrontal cortex (PFC) have been postmortem schizophrenic brains, mainly because of decreased dendritic arbor spine density. We assessed effects nBLA‐lesion on morphology PFC nucleus accumbens (NAcc) rats. nBLA...
Abstract Little has been investigated about the effects of stress on synaptic communication at prepubertal age, a stage considered as juvenile. This period development is related to socialization through play. Our group studied changes neuronal morphology in limbic structures caused by prenatal and early postnatal ages (before weaning) rat. In present study, we assessed effect restraint juvenile ages. Male Sprague–Dawley rats from day (PD) 21 PD35 were restrained (from movement) for 2 hrs....
Abstract A growing body of evidence suggests that growth hormone (GH) affects synaptic plasticity at both the molecular and electrophysiological levels. However, unclear is whether stimulated by GH associated with changes in neuron structure. This study investigated effect intracerebroventricular (ICV) administration on morphology pyramidal neurons CA1 region dorsal hippocampus layer III prefrontal cortex. Male Wistar rats received daily ICV injections (120 ng) for 7 days, they were...
Neonatal basolateral amygdala (nBLA) lesions in rats have been widely used as a neurodevelopmental model that mimics schizophrenia-like behaviors. Recently, we reported nBLA result significant decreases the dendritic spine number of layer 3 prefrontal cortex (PFC) pyramidal cells and medium spiny neurons nucleus accumbens (NAcc), which all changes after puberty. At present, aimed to evaluate effect this lesion CA1 ventral hippocampus (VH) 5 PFC. In order assess effects on morphology PFC VH...
Abstract Pregnancy is a complex process, involving number of hormones and trophic factors, many which are formed in the placenta. Several these factors have an effect at neuronal level, such as BDNF. Consequently, recent reports shown that exposure to (estrogen progesterone) BDNF exert neuroprotective effect. Here, we study pregnancies on dendritic morphology aged female rats (18 months age). Rats 18‐month‐old Sprague Dawley strain with zero, one, two, three gestations were evaluated for...
ABSTRACT Several studies in rodents have suggested the inactivation of subthalamic nucleus (STN) as an alternative strategy to Parkinson's disease (PD) treatment. The STN is part basal ganglia and plays important role motor function; however, recent data suggest that this structure has a critical cognitive function limbic system. receives direct projection from prefrontal cortex (PFC), interconnected with hippocampus both structures send excitatory projections accumbens (NAcc). Here, we...
Abstract Although individuals with schizophrenia typically present deficits in social interaction, little is known about the quality of their parent–infant interactions. In study, we assessed behavioral effects neonatal ventral hippocampus lesion (nVHL) female rats (nVHL to induce schizophrenia‐like males). Sexually naïve adult nVHL or sham received cognitive and tests, maternal behavior was observed independent groups on postpartum days 2, 6, 12. Compared Sham females, displayed elevated...
Ovariectomy (OVX) has been widely used to explore the effect of ovarian hormones on brain regions.It observed that estrogen in OVX rats increases dopaminergic function nucleus accumbens (NAcc).To determine whether absence or presence estradiol changes dendritic structure some neurons, we investigated consequences a daily injection for 2 weeks 17-beta (E2) morphology NAcc neurons two groups rats, immediately 10 administered after OVX.The dendrites was measured by using Golgi-Cox procedure...