A5039892564- Tryptophan and brain disorders
- 14-3-3 protein interactions
- Ion channel regulation and function
- Nicotinic Acetylcholine Receptors Study
- Plant Disease Resistance and Genetics
- Child and Adolescent Psychosocial and Emotional Development
- Advances in Cucurbitaceae Research
- Epigenetics and DNA Methylation
- Alzheimer's disease research and treatments
- Mental Health Treatment and Access
- Cannabis and Cannabinoid Research
- Bioinformatics and Genomic Networks
- Schizophrenia research and treatment
- Neuroscience and Neuropharmacology Research
- Biochemical effects in animals
- Stress Responses and Cortisol
- Suicide and Self-Harm Studies
National Institute of Genomic Medicine
2018-2025
McGill University
2021
Universidad Nacional Autónoma de México
2018
Autonomous University of Tlaxcala
2014
Benemérita Universidad Autónoma de Puebla
2014
Suicide is a significant public health problem, with increased rates in low- and middle-income countries such as Mexico; therefore, suicide prevention important. complex multifactorial phenomenon which biological social factors are involved. Several studies on the mechanisms of have analyzed proteome dorsolateral prefrontal cortex (DLPFC) people who died by suicide. The aim this work was to analyze protein expression profile DLPFC individuals comparison age-matched controls order gain...
Suicide represents a major health concern, especially in developing countries. While many demographic risk factors have been proposed, the underlying molecular pathology of suicide remains poorly understood. A body evidence suggests that aberrant DNA methylation and expression is involved. In this study, we examined profiles concordant gene changes prefrontal cortex Mexicans who died by suicide.In collaboration with coroner's office Mexico City, brain samples males (n = 35) age-matched...
Objective: To analyze sex differences in demographic and clinical characteristics of individuals who died by suicide Mexico City Method: Statistical analysis residents whose cause death was suicide, from January 2014 to December 2015, with a coroner's report. Suicide mortality rates were calculated age, sex, location within the city. The Chi-squared test used assess statistical differences. Results: From 990 (men: 78.28%, women: 21.72%). Among males, highest among groups 20 24 75 79 years...
Objective: Dual diagnosis (DD) is the co-occurrence of at least one substance use disorder and or more mental disorders in a given individual. Despite this comorbidity being highly prevalent associated with adverse clinical outcomes, its neurobiology remains unclear. Furthermore, patients DD are higher risk for suicidal behavior comparison single patients. Our objective was to evaluate brain gene expression patterns individuals who died by suicide. Methods: We compared profile dorsolateral...