Gary Chen

ORCID: 0000-0003-3057-9335
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About
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Research Areas
  • Energetic Materials and Combustion
  • Auditing, Earnings Management, Governance
  • RNA modifications and cancer
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Corporate Finance and Governance
  • Amino Acid Enzymes and Metabolism
  • Gastrointestinal disorders and treatments
  • Monoclonal and Polyclonal Antibodies Research
  • Financial Markets and Investment Strategies
  • Financial Reporting and XBRL
  • HER2/EGFR in Cancer Research
  • Molecular Biology Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Rocket and propulsion systems research
  • Thermal and Kinetic Analysis
  • Gas Dynamics and Kinetic Theory
  • Uterine Myomas and Treatments
  • Genetic Associations and Epidemiology
  • BRCA gene mutations in cancer
  • Chemical Analysis and Environmental Impact
  • Engineering and Material Science Research
  • Ferroptosis and cancer prognosis
  • Silicon Carbide Semiconductor Technologies
  • Corporate Taxation and Avoidance

The University of Queensland
2024

Nanjing Foreign Language School
2024

University of Liverpool
2024

University College London
2024

University of Houston
2024

Taiwan Semiconductor Manufacturing Company (United States)
2024

University of California, Riverside
2024

Pennsylvania State University
2023

DePaul University
2017-2022

University of Illinois Chicago
2013-2022

Significance We present a systematic study of family 15 types octahedral spinel electrocatalysts for the oxygen reduction reaction (ORR) in alkaline fuel cells. Three specific candidates, MnCo 2 O 4 /C, CoMn and CoFe exhibited very promising ORR activity. In particular, /C could rival activity selectivity Pt/C. Such performance was ascribed to partial charge transfer between Co Mn. The most active, unique Co–Mn core–shell structure with heterogeneous valence states, which were probed at...

10.1073/pnas.1906570116 article EN Proceedings of the National Academy of Sciences 2019-11-14

Abstract Antibody–drug conjugates (ADC) are emerging as powerful cancer treatments that combine antibody-mediated tumor targeting with the potent cytotoxic activity of toxins. We recently reported development a novel ADC delivers payload monomethyl auristatin E (MMAE) to cells expressing tissue factor (TF). By carefully selecting TF-specific antibody interferes TF:FVIIa-dependent intracellular signaling, but not procoagulant TF, an was developed (TF-011-MMAE/HuMax-TF-ADC) efficiently kills...

10.1158/1535-7163.mct-14-0798 article EN Molecular Cancer Therapeutics 2015-02-28

BACKGROUND Hepatitis B virus (HBV) patients with cirrhosis are at risk for developing costly, morbid, or mortal events, and therefore need highly effective therapies. Lamivudine is but limited by viral resistance. In contrast, adefovir entecavir have lower resistance, more expensive. The most cost-effective approach uncertain. METHODS We evaluated the cost-effectiveness of six strategies in HBV cirrhosis: (1) No treatment (“do nothing”), (2) lamivudine monotherapy, (3) (4) crossover to on...

10.1111/j.1572-0241.2006.00769.x article EN The American Journal of Gastroenterology 2006-09-01

We report room-temperature observations of $\mathrm{Cu_{Zn}}$-$\mathrm{V_{S}}$ quantum emitters in individual ZnS:Cu nanocrystals (NCs). Using time-gated imaging, we isolate the distinct, $\sim$3-$\mu$s-long, red photoluminescence (PL) emission defects, enabling their precise identification and statistical characterization. The exhibit distinct blinking photon antibunching, consistent with NCs containing two to four defects. emitters' PL spectra show a pronounced blue shift compared NC...

10.48550/arxiv.2501.11812 preprint EN arXiv (Cornell University) 2025-01-20

Heat spreaders can be made from natural graphite sheet materials. These take advantage of the anisotropic thermal properties graphite. Natural exhibits a high conductivity in plane combined with much lower through thickness sheet. As result, function as both heat spreader and an insulator used to eliminate localized hot spots electronic components. In some cases, replace conventional management system consisting sink cooling fan. This paper examines application these problems laptop...

10.1115/ipack2005-73073 article EN 2005-01-01

Abstract Embryonic diapause is a poorly understood phenomenon of reversible arrest embryo development prior to implantation. In many carnivores, such as the mink (Neovison vison), obligate characterizes each gestation. Embryo reactivation controlled by uterus mechanisms that remain elusive. Because polyamines are essential regulators cell proliferation and growth, it was hypothesized they trigger reactivation. To test this, mated females were treated with α-difluoromethylornithine, an...

10.1210/en.2010-0955 article EN Endocrinology 2011-02-08

In a flash: Pyrotechnic incendiary formulations with good stabilities toward various ignition stimuli have been developed without the need for barium or perchlorate oxidizers. KIO4 and NaIO4 were introduced as pyrotechnic oxidizers exhibited excellent performance. The periodate salts may garner widespread use in military civilian fireworks because of their low hygroscopicities high chemical reactivities.

10.1002/anie.201202589 article EN Angewandte Chemie International Edition 2012-05-25

This study reported preliminary clinical experience of using decelluarised nerve allograft material for repair digital defect in five hand injury patients. From October 2009 to July 2010, patients with traumatic were treated AxoGen® (AxoGen Inc, Alachua, FL) California Hospital Medical Center. All followed at least 12 months, and sensory recovery signs infection or rejection documented by a therapist. Average two-point discrimination was 6 mm, average Semmes-Weinstein Monofilaments test...

10.3109/2000656x.2013.778862 article EN Journal of Plastic Surgery and Hand Surgery 2013-07-15

Abstract The full‐up prototype testing of perchlorate‐free, hand‐held, signal illuminants for the US Army’s M126A1 red star parachute hand‐held is described. Compared to perchlorate‐containing control, disclosed yielded excellent stabilities toward various ignition stimuli while offering superior pyrotechnic performance. Militarily, provided further evidence that development smaller items in an environmentally conscious way a realistic and obtainable goal. results are also important from...

10.1002/chem.201102485 article EN Chemistry - A European Journal 2011-12-08

Pyrotechnic time delay compositions composed of boron carbide, sodium periodate, and polytetrafluoroethylene have been developed for use in the U.S. Army hand-held signal. The new were to replace currently used composition that contains potassium perchlorate barium chromate, chemicals are facing increasing regulatory scrutiny. Static tests aluminum signal housings demonstrated a wide range available inverse burning rates (1.3–20.8 s/cm), which includes 7–8.5 s/cm required signals. roles...

10.1021/sc400187h article EN ACS Sustainable Chemistry & Engineering 2013-07-16

ABSTRACT We examine how the adoption of eXtensible Business Reporting Language (XBRL) for financial reporting impacts pricing bank loans. Using a sample loans granted to U.S. borrowers from 2007–2013, we find that XBRL is associated with reduction in loan spreads. further spreads greater who have information inherently costlier process. Results difference-in-differences specification along other alternative research designs provide similar inferences. Subsequent adoption, show are lower...

10.2308/isys-51688 article EN Journal of Information Systems 2017-02-01

We investigated the interplay of matrix dynamics with molecular a thermally activated delayed fluorescence (TADF) emitter, NAI-DMAC, to identify factors that influence photophysical processes leading TADF. The surrounding NAI-DMAC molecules were varied continuously from liquid solid state by depositing toluene solutions containing poly(methyl methacrylate) (PMMA) and onto optical substrates. monitored changes emission as films dried form PMMA using temperature- time-resolved...

10.1021/jacs.3c11719 article EN Journal of the American Chemical Society 2023-11-13

Abstract Strontium salts are widely used in red flame pyrotechnic compositions, usually combined with perchlorate as oxidizer. The potential environmental impact of could be avoided by using high‐nitrogen compounds. Therefore, the following nitrogen‐rich strontium were prepared and characterized: tetrazolate pentahydrate ( 1 ), 1‐methyl‐5‐nitriminotetrazolate monohydrate 2 1‐(2‐chloroethyl)‐5‐nitriminotetrazolate 3 ). Their combustion behavior both color intensity purity investigated...

10.1002/prep.201010018 article EN Propellants Explosives Pyrotechnics 2010-06-01

Suicide represents a major health concern, especially in developing countries. While many demographic risk factors have been proposed, the underlying molecular pathology of suicide remains poorly understood. A body evidence suggests that aberrant DNA methylation and expression is involved. In this study, we examined profiles concordant gene changes prefrontal cortex Mexicans who died by suicide.In collaboration with coroner's office Mexico City, brain samples males (n = 35) age-matched...

10.1093/ijnp/pyab042 article EN cc-by-nc The International Journal of Neuropsychopharmacology 2021-06-30

The purpose of this paper is to propose a research model investigate the relationships between dynamic capabilities, business innovation, and performance. moderating role digital transformation in also examined. A total 262 managers Chinese small medium-sized enterprises (SMEs) were enrolled via an online questionnaire. Data scrutinized by partial least square structural equation modeling (PLS-SEM) using SmartPLS 3.0. findings study reveal that capabilities can positively affect innovation...

10.4018/jgim.350191 article EN Journal of Global Information Management 2024-08-05

Mutations in the nucleotide oligomerization domain-2 (NOD2) gene and positive antibodies to microbial antigens have been found be associated with Crohn's disease (CD) phenotype, fibrostenosis. The aim of this study was confirm these relationships a large cohort CD patients determine correlation between presence NOD2 variants oligomannan, CBir, outer membrane porin-C (OmpC), I2 fibrostenosis.Sera DNA from 731 unrelated were tested for (SNP 8, 12, 13) antibodies. results correlated phenotypes,...

10.1002/ibd.21196 article EN Inflammatory Bowel Diseases 2009-12-21
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