A5037671237- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Nanoparticle-Based Drug Delivery
- Advanced Drug Delivery Systems
- Porphyrin and Phthalocyanine Chemistry
- Advanced biosensing and bioanalysis techniques
- Lipid Membrane Structure and Behavior
- Polysaccharides Composition and Applications
- Cardiac Valve Diseases and Treatments
- Hydrogels: synthesis, properties, applications
- Bee Products Chemical Analysis
- Proteins in Food Systems
- Essential Oils and Antimicrobial Activity
- Cardiac and Coronary Surgery Techniques
- Neurological disorders and treatments
- Surfactants and Colloidal Systems
- Food Chemistry and Fat Analysis
- Graphene and Nanomaterials Applications
- Curcumin's Biomedical Applications
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Parkinson's Disease Mechanisms and Treatments
- Advancements in Transdermal Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Photoreceptor and optogenetics research
Universidade de São Paulo
2019-2024
Clinics Hospital of Ribeirão Preto
2021
Abstract Parkinson's disease (PD) is a progressive and chronic neurodegenerative of the central nervous system. Early treatment for PD efficient; however, long-term systemic medication commonly leads to deleterious side-effects. Strategies that enable more selective drug delivery brain using smaller dosages, while crossing complex brain-blood barrier (BBB), are highly desirable ensure efficacy decrease/avoid unwanted outcomes. Our goal was design test neurotherapeutic potential forefront...
This clinical study was developed to primarily evaluate the Complete Cytopathological Response Rate of Cervical Intraepithelial Neoplasms PDT using chitosan nanocapsules containing Chlorocyan-aluminum phthalocyanine as a photoactive agent. Analyses Free Recurrence Interval, toxicity profile (immediate and late), complications were secondarily analyzed.This previously approved by National Council Ethics in Research Brazil (CONEP), on May 28, 2014, under case number 19182113.4.0000.5009. On...
mTOR is a signaling pathway involved in cell survival, stress response, and protein synthesis that may be key point sepsis-induced cardiac dysfunction. Curcumin has been reported vitro as an inhibitor compound; however, there are no studies demonstrating this effect experimental sepsis. Thus, study aimed to evaluate the action of curcumin on heart septic mice. Free (FC) nanocurcumin (NC) were used, samples obtained at 24 120 h after Histopathological ultrastructural analysis showed...
Lysosomes are organelles with many functions in cell metabolism, the morphology changes as a function of different cellular mechanisms. Some enzymes lysosomal medium responsible for digestion process. This work reports new biocompatible lysosome, tracker, long-life fluorescence emission. They were investigated by steady-state, time-resolved spectroscopic, and confocal microscopy analysis organic biological mediums. It was observed that probe could already be used at low concentrations to...