A5077794393- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Gastrointestinal disorders and treatments
- Abdominal Surgery and Complications
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Diseases and Immunity
- SARS-CoV-2 and COVID-19 Research
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Intestinal Malrotation and Obstruction Disorders
- Pharmaceutical studies and practices
- Palliative Care and End-of-Life Issues
- Liver Disease and Transplantation
- Child Nutrition and Feeding Issues
- Eosinophilic Esophagitis
- Electrolyte and hormonal disorders
- COVID-19 Clinical Research Studies
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Cancer Immunotherapy and Biomarkers
- Management and Marketing Education
- Infectious Encephalopathies and Encephalitis
- Childhood Cancer Survivors' Quality of Life
Singapore General Hospital
2016-2024
SingHealth
2023
Duke-NUS Medical School
2021-2022
Hospital Universitario Ramón y Cajal
2012-2022
Toronto General Hospital
2020-2021
University of Toronto
2020-2021
University of Houston
2011
Instituto Nacional de Cardiología
1987
Abstract Background Desensitization to antineoplastic agents is becoming a standard of care. Efforts establish and improve these techniques are being made at many institutions. Our aims evaluate new rapid desensitization protocol designed be shorter (approximately 4 h) safer (reducing hazardous drugs exposure risks) assess the oxaliplatin‐specific immunoglobulin E ( I g ) as novel diagnostic tool. Methods Prospective, observational, longitudinal study with patients who, for 1‐year period,...
BACKGROUNDPatients undergoing immune-modifying therapies demonstrate a reduced humoral response after COVID-19 vaccination, but we lack proper evaluation of the effect such on vaccine-induced T cell responses.METHODSWe longitudinally characterized and spike-specific responses in patients with inflammatory bowel disease (IBD), who were antimetabolite therapy (azathioprine or methotrexate), TNF inhibitors, and/or other biologic treatment (anti-integrin anti-p40) for up to 6 months completing...
Abstract Background and study aims Endoscopic treatment of non-variceal upper gastrointestinal bleeding (NVUGIB) with high-risk adverse outcome (HR-AO) features has a high risk failure. We studied the safety efficacy over-the-scope clips (OTSC) to treat these lesions. Patients methods included patients who were treated using OTSC for NVUGIB from January 2015 October 2017. rebleeding mortality rates used Rockall data our institution’s prior comparison. descriptive chi-square statistics....
Palliative surgical oncology patients represent a unique group with complex needs who often require multidisciplinary input for the provision of timely and holistic care. The authors assembled multi-disciplinary palliative intervention team evaluated its association quality discussions on goals care (GOC) among advanced cancer undergoing interventions.This prospective cohort study analyzed interventions at single urban academic center from October 2019 to March 2022. In January 2021,...
Abstract Background Dietary beliefs and behaviors in IBD patients may affect both clinical outcome psychosocial aspect of patients’ lives. New emerging studies have shown varying efficacy different diets inducing maintaining remission patients. This study aims to investigate the dietary beliefs, barriers, acceptability diet among Asia-Pacific region. Methods A multi-centre survey was conducted across 4 countries Asia-Pacific. An anonymized online electronic disseminated at 10 participating...
Iturbe-Alessio, I.; C. Fonseca, M. Del; Mutchinik, O.; Santos, A.; Zajarias, Salazar, E. Author Information
Autoimmune hepatitis (AIH) is an immune-mediated liver disease of unknown etiology. Increasing incidence AIH in Asian patients has been reported. However, the phenotypic difference Europe and Asia still not explored. To evaluate clinical presentation, biochemical immunological profiles, treatment response survival outcome type 1 from two tertiary transplant centres (United Kingdom Singapore). Patients who fulfilled simplified diagnostic scoring criteria were included study. with overlap...
Abstract Introduction Severe gastrointestinal dysmotility disorder (GID) constitute approximately 20% of patients requiring home parenteral nutrition (HPN), whereas short‐bowel syndrome (SBS) remains the most frequent indication for HPN. This study's aim was to characterize GID and compare clinical parameters survival SBS patients. Similarly, comparisons between sclerodermaand nonscleroderma were made. Methods Demographic data all extracted from Canadian HPN Registry January 1, 2003,...
Duodenal duplication cysts are rare.1Chen J.J. Lee H.C. Yeung C.Y. et al.Meta-analysis: the clinical features of duodenal cyst.J Pediatr Surg. 2010; 45: 1598-1606Abstract Full Text PDF PubMed Scopus (81) Google Scholar Definitive endoscopic therapy and marsupialization symptomatic have been reported with use a needle-knife, sphincterotome, or polypectomy snare.2Antaki F. Tringali A. Deprez P. al.A case series intraluminal cysts: presentation, long-term outcome (with video).Gastrointest...
Home parenteral nutrition (HPN) is a life sustaining therapy for patients with chronic intestinal failure. Reported outcomes Asian HPN are scarce. We aim to review the clinical of adult and paediatric in our cohort which caters 95% Singaporean patients.This retrospective from an (2002-2017) (2011-2017) largest tertiary PN centres Singapore. Patient demographics were reviewed.There 41 8 patients. Mean age was 53.0(±15.1) (adults) 8(±1.8) years-old (paediatrics). duration 2.6(±3.5) 3.5(±2.5)...
Duodenal duplication cysts are rare congenital foregut anomalies, accounting for 2%–12% of all gastrointestinal tract duplications. Surgical excision entails risk injury to the pancreaticobiliary structures due proximity or communication with cyst. We present a case duodenal cyst in 3 year-old boy who successfully underwent endoscopic decompression. AT is young first presented at 15 months age abdominal pain. There was one subsequent episode pancreatitis. Ultrasonography showed typical...
In line with recent guidance from the American Society for Parenteral and Enteral Nutrition (ASPEN) European Clinical Metabolism (ESPEN) to minimize healthcare team exposure by clustering care relying on other providers or telehealth collect relevant nutrition assessments, our support has adopted a modified workflow using information technology provide parenteral (PN) remotely in safe timely manner. We aim compare prescribing adequacy PN-related complications before during coronavirus...
By March 12th 2020, the World Health Organization declared coronavirus disease (COVID-19) a global pandemic [[1]World OrganisationCoronavirus (COVID 19) pandemic.2020https://www.who.int/emergencies/diseases/novel-coronavirus-2019Google Scholar]. In February Singapore had highest number of confirmed cases outside China, but has since been overtaken by other countries Vigilant steps were taken healthcare workers to limit exposure whilst delivering essential care hospitalized patients. This...
Takotsubo cardiomyopathy usually occurs as a result of catecholamine release causing myocardial ‘stunning’ during physical or emotional stress. Typically coronary angiogram shows normal minor artery disease and echocardiogram apical ballooning with basal wall hyperkinesia. The prognosis is excellent good cardiac functional recovery within days to weeks. We report the first case takotsubo in patient acute-on-chronic liver failure.
<h3>Objectives</h3> To examine the associations of psychosocial and physical work factors with musculoskeletal symptoms (MSKs) among maquila workers. <h3>Methods</h3> As part longitudinal CUPID-INCA, 900 nurses, office workers workers, aged 20–59 years, were interviewed at baseline using computer assisted personal interview. Using validated questions, we asked about low back (LBP) upper extremity (UEP) pain in last 30 days, work, health beliefs. We used logistic regression models....
<h3>Background</h3> Dabigatran etexilate (DE) is a new oral anticoagulant. It was included in the hospital9s formulary as restricted-use drug December 2009. <h3>Purpose</h3> To analyse DE use, compliance with authorised indications and use restrictions, to quantify incidence of adverse events. <h3>Materials methods</h3> An observational, prospective, utilisation study carried out over four months general tertiary care hospital. The Pharmacy Therapeutics Committee approved DE, prescriptions...