A5072204293- Pelvic floor disorders treatments
- Gastrointestinal motility and disorders
- Clinical Nutrition and Gastroenterology
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Pelvic and Acetabular Injuries
- Acute Myocardial Infarction Research
- Dysphagia Assessment and Management
- Diverticular Disease and Complications
- Anorectal Disease Treatments and Outcomes
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Abdominal Surgery and Complications
- Congenital gastrointestinal and neural anomalies
- Vasculitis and related conditions
- Eosinophilic Disorders and Syndromes
- Body Composition Measurement Techniques
- Hernia repair and management
- Dialysis and Renal Disease Management
- Effects of Vibration on Health
- Pressure Ulcer Prevention and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- Natural Compound Pharmacology Studies
- Colorectal Cancer Treatments and Studies
- Heart Failure Treatment and Management
Toronto General Hospital
2020
University of Toronto
2020
University Health Network
2018
Queen's University
2018
Mayo Clinic in Arizona
2012-2017
Mayo Clinic Hospital
2013-2015
Mayo Clinic in Florida
2015
WinnMed
2012-2015
Mayo Clinic
2012
John Paul II Hospital
2010
OBJECTIVES: High-resolution manometry (HRM) is used to measure anal pressures in clinical practice but normal values have not been available. Although rectal evacuation assessed by the rectoanal gradient during simulated evacuation, there substantial overlap between healthy people and defecatory disorders, effects of age are unknown. We evaluated on anorectal balloon expulsion women. METHODS: Anorectal (HRM), sensation, time (BET) were 62 asymptomatic women ranging from 21 80 years (median...
Millions of Americans regularly use herbal supplements, but many are unaware the potential hidden dangers. Numerous supplements have been associated with hepatotoxicity and, indeed dietary/herbal represent an increasingly common source acute liver injury. We report a case failure requiring transplantation Garcinia cambogia, supplement widely promoted for weight loss. When patients present hepatitis or from unknown etiology, careful history should be performed.
Abstract Background Defecatory disorders ( DD ) are defined by clinical and objective features of impaired rectal evacuation. The epidemiology in the population is unknown, partly because many constipated patients do not undergo anorectal tests. Our objectives were to estimate incidence rate community. Methods We reviewed medical records all older than 16 years Olmsted County, MN , who had constipation underwent manometry from 1999 through 2008. Criteria for diagnosing 6 months or longer one...
Abstract Background Symptoms suggestive of gastroparesis are non‐specific and conflicting reports exist regarding the ability symptoms to predict presence gastroparesis. Our aim, therefore, was evaluate relationships between gastroparetic their impact on quality life determine relationship with clinical factors gastric emptying. Methods Gastric emptying scintigraphy, sociodemographic features, health care resource utilization, symptoms, using validated questionnaires were obtained from...
Abstract Background A 50% or greater reduction in the frequency of fecal incontinence ( FI ) recorded with daily bowel diaries is primary endpoint clinical trials . Whether this difference clinically important unknown. The relationship between symptoms and weekly instruments contribution psychological factors to quality life QOL unclear. Methods Fecal severity was assessed periodic questionnaires (fecal score [ FISS ], FIQOL , 36‐Item Short Form Health Survey SF ‐36], hospital anxiety...
Abstract Background Inter‐observer variability limits the reproducibility of pelvic floor motion measured by magnetic resonance imaging (MRI). Our aim was to develop a semi‐automated program measuring in reproducible and refined manner. Methods Pelvic anatomy during voluntary contraction (squeeze) rectal evacuation were assessed MRI 64 women with fecal incontinence (FI) age‐matched controls. A radiologist anorectal angles junction motion. did same also dissected into perpendicular vectors...
Fructose consumption has increased by one-third from 1978 to 2004 in the western diet.1 It been implicated epidemic of obesity, and associated with elevated fasting blood sugar levels hypertension.2 In addition, fructose is thought trigger functional abdominal pain diarrhea susceptible individuals via gas production its fermentation bacteria gut, intraluminal osmotic load.3 Recently, a diet low fermentable oligosaccharides, disaccharides, monosaccharides polyols, which includes restriction,...
Survival of patients with short-bowel syndrome (SBS) receiving home parenteral nutrition (HPN) and associated factors have not been reported recently in North America. The objective this study was to determine the long-term survival adult SBS as primary indication for HPN assess that may affect by using Canadian Registry.This is a retrospective analysis prospectively collected data extracted from registry, prior approval teduglutide Canada. Using only incident cases, probabilities were...
Background: Heart is frequently involved in Churg‐Strauss syndrome (CSS). However, the mechanics of left ventricular (LV) dysfunction CSS has not been studied. Objective: To assess LV function and to characterize contribution longitudinal, circumferential rotational deformation CSS. Methods: We enrolled 22 patients (eight males, mean age 43.2 ± 9.5 years) remission their disease sex‐ age‐matched healthy subjects. All underwent conventional two‐dimensional speckle‐tracking echocardiography....
Abstract Introduction Severe gastrointestinal dysmotility disorder (GID) constitute approximately 20% of patients requiring home parenteral nutrition (HPN), whereas short‐bowel syndrome (SBS) remains the most frequent indication for HPN. This study's aim was to characterize GID and compare clinical parameters survival SBS patients. Similarly, comparisons between sclerodermaand nonscleroderma were made. Methods Demographic data all extracted from Canadian HPN Registry January 1, 2003,...
A seventy-seven year old man with a history of metastatic melanoma, on chemotherapy ipilimumab presented chief complaint abdominal pain and diarrhea. His symptoms began six weeks after initiation ipilimumab. He described the diarrhea as watery, non-bloody bowel movements occurring 3-4 times day. CT his abdomen revealed diffusely dilated colon pericolonic stranding distention transverse (Image 1). Initially, he was treated antibiotics, ciprofloxacin metronidazole without improvement. Stool...
IBD is a chronic illness that can have variable course of disease progression. Studies show up to 11% patients receive care not recommended in guidelines and potentially harmful. Hence there need improve quality by standardizing care, be quantified. AGA/CCFA has endorsed set IBD-specific process-measures are currently incorporated into the Physician Quality Reporting System (PQRS). In year 2012 2013, our group adopted standardized worksheet based on 10 highest yielding QMs (sample Figure1)....
Purpose: A 22-year-old female developed dyspnea with an inability to keep up her peers in gradeschool. At age 18, she noted slowly progressive dysphagia both solids and liquids the sensation that food would ‘stick' upper chest ‘like a bubble my throat'. She reported frequent belching especially lying supine, occasionally regurgitation. Barium esophagram demonstated posterior compression of thoracic esophagus (white arrow, panel A). An aberrant right subclavian artery originating from aorta...