A5045257157- biodegradable polymer synthesis and properties
- Additive Manufacturing and 3D Printing Technologies
- Microplastics and Plastic Pollution
- 3D Printing in Biomedical Research
- Carbon dioxide utilization in catalysis
- Drug Solubulity and Delivery Systems
- Nanocomposite Films for Food Packaging
- Polymer crystallization and properties
- Innovative Microfluidic and Catalytic Techniques Innovation
- Electrospun Nanofibers in Biomedical Applications
- Advanced Cellulose Research Studies
- Nonlinear Optical Materials Research
- Thermal and Kinetic Analysis
- Tribology and Wear Analysis
- Computational Drug Discovery Methods
- Plant Surface Properties and Treatments
- Recycling and Waste Management Techniques
- Corneal Surgery and Treatments
- Biochemical and Molecular Research
- Essential Oils and Antimicrobial Activity
- Biosimilars and Bioanalytical Methods
- Vascular Malformations and Hemangiomas
- Ocular Surface and Contact Lens
- Injection Molding Process and Properties
- Bee Products Chemical Analysis
Universidade de Brasília
2022-2025
Universidade Federal de Santa Catarina
2015-2022
Materials Research Group (United States)
2016
Background/Objectives: Chagas disease is a neglected tropical caused by infection with the parasite Trypanosoma cruzi. Benznidazole and nifurtimox are only approved drugs for treating this condition, but their low aqueous solubility may lead to erratic bioavailability. This work aimed first time formulate tablets of hot melt extrusion coupled 3D printing as strategy increase drug dissolution production dosage on demand. Methods: Different pharmaceutical-grade polymers were evaluated through...
The in-situ formation of nanoparticles from polymer-based solid medicines, although previously described, has been overlooked despite its potential to interfere with oral drug bioavailability. Such polymeric pharmaceuticals are becoming increasingly common on the market and can become even more popular due dizzying advance 3D printing medicines. Hence, this work aimed study phenomenon during dissolution printed tablets produced three different polymers, hydroxypropylmethylcellulose acetate...
The barrier and mechanical properties of polymer matrices are affected by the crystallization kinetics incorporation nanoparticles can modify nucleation density as well rate mechanism crystallization.In this study, a nanocomposite poly(lactic acid) (PLA) containing cellulose nanocrystals (CNC) was prepared in order to evaluate effect CNC content on matrix.Dimethylformamide, solvent PLA, used replace aqueous medium for dispersion CNC, facilitate preparation PLA films with dispersed CNC.Higher...
A novel sanitizer tablet containing clove essential oil (CO) microemulsion was developed. preformulation study using nuclear magnetic resonance and thermal analyses showed component compatibility. The main components of the samples remained intact despite a color change, probably due to strong acid-base interaction between eugenol diethanolamine. CO acaricidal larvicidal activities superior commercial product, with product efficacy 99.9% larvae mortality 94%. Optimal spray-drying conditions...
The Covid-19 pandemic situation has contributed to sparking discussions about an increase in packaging combined with the nonrecommendation of reuse. For this reason, many countries have encouraged use biodegradable polymers. In study, blends poly(lactic acid) (PLA) and poly(vinyl alcohol) (PVAL) were prepared at 80/20 (w/w) presence specific amounts monobutyl maleate (MBM) as a compatibilizer. All these components are proven biodegradable. PLA/PVAL/MBM blend films obtained by thermopressing,...
Whiskers have been used as a nanomaterial dispersed in polymer matrices to modify the microscopic and macroscopic properties of polymer. These nanomaterials can be isolated from cellulose, one most abundant natural renewable sources biodegradable In this study, whiskers were sugarcane bagasse corn cob straw fibers. Initially, cellulose fiber was treated through an alkaline/oxidative process followed by acid hydrolysis. Dimethylformamide dimethyl sulfoxide replace aqueous medium for...
Pluronic ® F127 nanoparticles were loaded with citronella essential oil (CEO) and then covered chitosan-sodium alginate polyelectrolyte complex (PEC).The system was characterized according to size, zeta potential stability over time.Dynamic light scattering (DLS) in different proportions of water/ethanol as a dispersive medium important confirming that PEC the nanoparticles.Infrared spectroscopy also indicated interaction PEC.The nanoparticle size evaluated by transmission electron...
Poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) are two immiscible polymers which biodegradable bioabsorbable, being therefore widely applied for medical materials. The formation of homogeneous fibers PCL by electrospinning represents a difficult task due to the low viscosity solutions this polymer in comparison PLA solutions. In addition, development simple techniques characterization these systems field interest. paper, nanofibers PLA/PCL (1:1 w/w) CHCl3:MeOH (3:1 solvent system...