A5042585569- Drug Solubulity and Delivery Systems
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Pharmaceutical studies and practices
- Trypanosoma species research and implications
- Dermatology and Skin Diseases
- Bee Products Chemical Analysis
- Microencapsulation and Drying Processes
- Injection Molding Process and Properties
- Phytochemistry Medicinal Plant Applications
- Analytical Methods in Pharmaceuticals
- Advanced Drug Delivery Systems
- Protein purification and stability
- Research on Leishmaniasis Studies
- Phytochemistry and Biological Activities
- Public Health in Brazil
- Wound Healing and Treatments
- Natural Compounds in Disease Treatment
- Botany, Ecology, and Taxonomy Studies
- Skin Protection and Aging
- Surgical Sutures and Adhesives
- Hair Growth and Disorders
- Nail Diseases and Treatments
Universidade de Brasília
2016-2025
Brazilian Agricultural Research Corporation
2022
Escola Superior de Enfermagem de Lisboa
2022
Universidade de Santiago de Compostela
2007-2017
Universidade Federal de Mato Grosso
2011
Background/Objectives: This study aimed to develop gel nanoemulsions (NEs) of Brazilian essential oils (EOs) from Eugenia uniflora and Psidium guajava, as well perform chemical characterization investigate the antimicrobial activity EOs NEs. Results/Conclusions: The main compounds E. EO were curzerene (34.80%) germacrene B (11.92%), while those P. guajava β-caryophyllene (25.92%), β-selinene (22.64%), γ-selinene (19.13%). NEs had droplet sizes 105.30 99.50 nm polydispersity index (PDI)...
Introdução: A injúria renal aguda é uma condição na qual os rins tem dificuldade em desempenhar suas funções básicas. Trata-se de doença caracterizada por um abrupto declínio da função renal. Estima-se que a ocorra aproximadamente 20% dos pacientes admitidos unidades terapia intensiva, sendo associada alto risco morbidade e mortalidade. O objetivo do estudo foi analisar evidências científicas sobre efeitos anti-inflamatórios implicações prevenção recuperação Injúria Renal Aguda. Métodos:...
The in-situ formation of nanoparticles from polymer-based solid medicines, although previously described, has been overlooked despite its potential to interfere with oral drug bioavailability. Such polymeric pharmaceuticals are becoming increasingly common on the market and can become even more popular due dizzying advance 3D printing medicines. Hence, this work aimed study phenomenon during dissolution printed tablets produced three different polymers, hydroxypropylmethylcellulose acetate...
The aim of this study was to evaluate the physicochemical composition and antibacterial activity Brazilian propolis extracts from different types, concentrations, extraction solvents regions in Brazil. A total 21 samples were analyzed, comprising 14 Apis mellifera (12 green, 1 brown, red) 7 stingless bees (3 mandaçaia, 2 jataí, hebora, tubuna). analyses performed dry extract, phenolic content (TPC) antioxidant (DPPH ABTS). by Determination Minimal Inhibitory Concentration (MIC) Bactericidal...
Abstract Objectives Benznidazole (BNZ), the primary chemotherapy agent used to treat Chagas disease, has poor aqueous solubility, which results in low bioavailability. The purpose of this work was develop stable effervescent tablets using an inclusion complex BNZ with cyclodextrin (CD). Method In first phase, different CDs were evaluated according their ability improve solubility BNZ. Then, complexes solid state produced by kneading method and several physical–chemical assays. Finally,...
One of the challenges in developing three-dimensional printed medicines is related to their stability due manufacturing conditions involving high temperatures. This work proposed a new protocol for preformulation studies simulating thermal processing and aging medicines, tested regarding morphology thermal, crystallographic, spectroscopic profiles. Generally, despite strong drug-polymer interactions observed, chemical model drugs was preserved under such conditions. In fact, metoprolol...