A5004187760- Long-Term Effects of COVID-19
- Pesticide Exposure and Toxicity
- COVID-19 Impact on Reproduction
- COVID-19 Clinical Research Studies
- Insect Pest Control Strategies
- Mosquito-borne diseases and control
- COVID-19 and Mental Health
- Advancements in Transdermal Drug Delivery
- Peripheral Neuropathies and Disorders
- Leprosy Research and Treatment
- Natural product bioactivities and synthesis
- Transgenic Plants and Applications
- Sepsis Diagnosis and Treatment
- Advanced Drug Delivery Systems
- Viral Infections and Vectors
- Pregnancy and preeclampsia studies
- Crystallization and Solubility Studies
- Blood properties and coagulation
- Reproductive System and Pregnancy
- Bioactive natural compounds
- Drug Solubulity and Delivery Systems
- Climate Change and Health Impacts
- Phytochemistry and Biological Activities
- Analytical Chemistry and Chromatography
- Phytochemicals and Medicinal Plants
Universidade de Brasília
2016-2025
University of Basel
2023
Abstract Background Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about impact of possible co-infections. Methods Thirteen SARS-CoV-2/DENV co-infection cases reported Midwestern Brazil between April September 2020 are described. Information was gathered from hospital medical records regarding most relevant...
In patients with severe forms of COVID-19, thromboelastometry has been reported to display a hypercoagulant pattern. However, an algorithm differentiate COVID-19 from nonsevere and healthy controls based on parameters not developed. Forty-one over 18 years age positive qRT-PCR for SARS-CoV-2 were classified according the severity disease: (NS, n = 20) or (S, 21). A control (HC, 9) group was also examined. Blood samples all participants tested by extrinsic (EXTEM), intrinsic (INTEM),...
Experts have called attention to the possible negative impact of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome on progression leprosy-related disabilities. We assessed frequency reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory (SARS) (CoV) 2 (SARS-CoV-2). consecutively included during first peak COVID-19 epidemic Brazil analyzed expressions genes encoding interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-12A, IL-12B, tumor...
In early 2020, the COVID-19 pandemic paralyzed world and exposed fragility of health systems in face mass illness. Health professionals became protagonists, fulfilling their mission at risk physical mental The study aimed to evaluate absenteeism indirectly related SARS-CoV-2 infection a large population care professionals.An observational longitudinal repeated measures was performed, including workers linked 40 public university hospitals Brazil. All causes were analyzed, focusing on those...
SARS-CoV-2 infection during pregnancy can induce changes in the maternal immune response, with effects on outcome and offspring. This is a cross-sectional observational study designed to characterize immunological status of pregnant women convalescent COVID-19 at distinct trimesters. The focused providing clear snapshot interplay among serum soluble mediators.A sample 141 from all prenatal periods (1st, 2nd 3rd trimesters) comprised patients 3-20 weeks after symptoms onset (COVID, n=89)...
In a screening of small library extracts from plants the Amazonian and Cerrado biomes, hexane extract Connarus tuberosus roots was found to significantly potentiate GABA induced fluorescence in (FLIPR) assay CHO cells stably expressing α1β2γ2 subtype human GABAA receptors. With aid HPLC-based activity profiling linked neolignan connarin. connarin not abolished by increasing concentrations flumazenil, while effect diazepam increased The pregnenolone sulfate (PREGS) concentration-dependent...
The present study applied distinct models of descriptive analysis to explore the integrative networks and kinetic timeline serum soluble mediators select a set systemic biomarkers applicable for clinical management COVID-19 patients. For this purpose, total 246 participants (82 164 healthy controls - HC) were enrolled in prospective observational study. Serum quantified by high-throughput microbeads array on hospital admission (D0) at consecutive timepoints (D1-6 D7-20). results reinforce...