A5074713635- COVID-19 Clinical Research Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- ATP Synthase and ATPases Research
- Blood properties and coagulation
- S100 Proteins and Annexins
- Viral Infectious Diseases and Gene Expression in Insects
- Adipokines, Inflammation, and Metabolic Diseases
- Climate Change and Health Impacts
- Insect Resistance and Genetics
- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Long-Term Effects of COVID-19
- Immune responses and vaccinations
- Plant Pathogens and Fungal Diseases
- Radiopharmaceutical Chemistry and Applications
- Nanoparticle-Based Drug Delivery
- CRISPR and Genetic Engineering
- COVID-19 and healthcare impacts
- Dendrimers and Hyperbranched Polymers
- Venomous Animal Envenomation and Studies
- RNA Interference and Gene Delivery
- Nanoparticles: synthesis and applications
- Plant Pathogenic Bacteria Studies
- Advanced Nanomaterials in Catalysis
Universidade de Brasília
2018-2025
Laboratoire de Biochimie
2021
In patients with severe forms of COVID-19, thromboelastometry has been reported to display a hypercoagulant pattern. However, an algorithm differentiate COVID-19 from nonsevere and healthy controls based on parameters not developed. Forty-one over 18 years age positive qRT-PCR for SARS-CoV-2 were classified according the severity disease: (NS, n = 20) or (S, 21). A control (HC, 9) group was also examined. Blood samples all participants tested by extrinsic (EXTEM), intrinsic (INTEM),...
Intestinal ischemia and reperfusion injury is a model system of possible consequences severe trauma surgery, which might result into tissue dysfunction organ failure. Neutrophils contribute to the injuries preceded by reperfusion. However, mechanisms intestinal stimulate activate circulating neutrophils still not clear. In this work, we used proteomics approach explore underlying regulated in Wistar rat after We isolated from three different biological groups; control, sham laparotomy,...
In recent years, the number of new antimicrobial drugs launched on market has decreased considerably even though there been an increase in resistant microbial strains. Thus, resistance become a serious public health problem. Amphibian skin secretions are rich source host defense peptides, which generally cationic and hydrophobic molecules, with broad-spectrum activity. this study, one novel multifunctional peptide was isolated from secretion Chaco tree frog, Boana raniceps. Figainin 2...
Intestinal ischemia reperfusion injury (iIRI) is a severe clinical condition presenting high morbidity and mortality worldwide. Some of the systemic consequences IRI can be prevented by applying ischemic preconditioning (IPC), series short ischemia/reperfusion events preceding major ischemia. Although neutrophils are key players in pathophysiology injuries, neither dysregulation presented these cells iIRI nor protective effect iIPC have their regulation mechanisms fully understood. Protein...
Background, Leucoptera coffeella (Guerin-Meneville, 1842) is a moth species (Lyonetiidae, Lepidoptera) pest that causes severe losses to coffee crops. Further information about its genomic data required allow molecular strategies for the development of sustainable pesticides and gain in-depth knowledge on phylogenetics. However, closest complete genome available within superfamily level (Yponomeutoidea). Here we report generation first long-read genome, transcriptome proteome results L. in...
Background Since the beginning of COVID-19 pandemic, world’s attention has been focused on better understanding relation between human host and SARS-CoV-2 virus, as its action led to hundreds thousands deaths. Objective In this context, we decided study certain consequences abundant cytokine release over innate adaptive immune systems, inflammation, hemostasis, comparing mild severe forms COVID-19. Methods To accomplish these aims, will analyze demographic characteristics, biochemical tests,...
Neutrophils are known as one of the first lines defense in innate immune response and can perform many particular cellular functions, such chemotaxis, reverse migration, phagocytosis, degranulation cytotoxic enzymes metabolites, release DNA neutrophil extracellular traps (NETs). not only have tightly regulated signaling themselves, but also participate regulation other components system. As fresh neutrophils terminally differentiated, short-lived, highly variable among individuals, it is...
<sec> <title>BACKGROUND</title> Since the beginning of COVID-19 pandemic, world’s attention has been focused on better understanding relation between human host and SARS-CoV-2 virus, as its action led to hundreds thousands deaths. </sec> <title>OBJECTIVE</title> In this context, we decided study certain consequences abundant cytokine release over innate adaptive immune systems, inflammation, hemostasis, comparing mild severe forms COVID-19. <title>METHODS</title> To accomplish these aims,...
In patients with severe forms of COVID-19, thromboelastometry has been reported to display a hypercoagulant pattern. However, an algorithm differentiate COVID-19 from nonsevere and healthy controls based on parameters not developed. Forty-one over 18 years age positive qRT-PCR for SARS-CoV-2 were classified according the severity disease: (NS, n=20) or (S, n=21). A control (HC, n=9) group was also examined. Blood samples all participants tested by extrinsic (EXTEM), intrinsic (INTEM),...