A5102883697- Inflammatory Bowel Disease
- Microscopic Colitis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Helicobacter pylori-related gastroenterology studies
- Clinical Nutrition and Gastroenterology
- Autoimmune and Inflammatory Disorders
- Digestive system and related health
- Immunodeficiency and Autoimmune Disorders
- Nutrition and Health in Aging
- Eosinophilic Esophagitis
- Fatty Acid Research and Health
- Gastrointestinal motility and disorders
- Celiac Disease Research and Management
- Diet and metabolism studies
- Cytomegalovirus and herpesvirus research
- Systemic Lupus Erythematosus Research
- Gut microbiota and health
- Mycobacterium research and diagnosis
- Acute Lymphoblastic Leukemia research
- Pregnancy and Medication Impact
- Viral gastroenteritis research and epidemiology
- Gastrointestinal disorders and treatments
- Metabolism and Genetic Disorders
- Liver Diseases and Immunity
Hospital Universitari Germans Trias i Pujol
2012-2022
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2007-2020
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2010-2019
Centro de Investigación Biomédica en Red
2015-2018
Centre for Biomedical Network Research on Rare Diseases
2018
Groupe d'Étude Thérapeutique des Affections Inflammatoires du Tube Digestif
2018
Universitat Autònoma de Barcelona
2000-2017
Istituti di Ricovero e Cura a Carattere Scientifico
2013
Baxter (Australia)
2012
Texas A&M University
2012
To evaluate the safety of thiopurines in patients with inflammatory bowel disease. identify predictive factors associated development thiopurine-induced adverse events.Long-term incidence events was estimated from a prospectively maintained Spanish nationwide database using Kaplan-Meier analysis. Cox regression analysis performed to potential events.Three thousand nine hundred and thirty-one were included. Ninety-five percent on azathioprine. The median follow-up 44 months (range, 0-420)....
Steroids are recommended in severe alcohol-induced hepatitis, but some data suggest that artificial nutrition could also be effective. We conducted a randomized trial comparing the short- and long-term effects of total enteral or steroids these patients. A 71 patients (80% cirrhotic) were to receive 40 mg/d prednisolone (n = 36) tube feeding (2,000 kcal/d) for 28 days 35), followed 1 year until death. Side treatment occurred 5 on 10 (not significant). Eight enterally fed prematurely...
<h3>ABSTRACT</h3> Some insects use endogenous reverse transcriptase (RT) to make variable viral copy DNA (vcDNA) fragments from RNA in linear (lvcDNA) and circular (cvcDNA) forms. The latter form is easy extract selectively. vcDNA produces small interfering (siRNA) variants that inhibit replication via the interference (RNAi) pathway. also autonomously inserted into host genome as elements (EVE) can result RNAi. We hypothesized similar mechanisms occurred shrimp. used insect methods giant...
BackgroundCytomegalovirus (CMV) infection has been reported in ulcerative colitis (UC), especially severe, steroid-refractory disease. However, its role steroid-refractoriness remains unknown. Our goals were to evaluate the prevalence of CMV disease UC, best diagnostic strategy, and influence activity and/or treatment development.
BackgroundFecal calprotectin (FC) is considered the best noninvasive way to assess disease activity in ulcerative colitis (UC). However, it not known which more suitable moment for stool sampling patients with increased frequency. The aims of this study were intraindividual variation FC within day and evaluate if first bowel movement morning sample measurement acute flares UC.
Deranged intestinal motility, which occurs in cirrhosis, may facilitate the development of bacterial overgrowth (IBO), can lead to translocation (BT). To assess effect cisapride on IBO and BT cirrhotic rats received or a placebo for 7 days, measurements jejunal content studies were performed. In addition, fluid from 46 patients was obtained quantitative culture. Those whom gram-negative detected randomized receive not (20 mg twice per day) 1 week. Cisapride significantly reduced rats. no...
OBJECTIVE: It has been suggested that, in inflammatory bowel disease, cytomegalovirus behaves the intestine as a nonpathogenic bystander, and even its finding intestinal mucosa unclear clinical relevance. We report our experience with small series of patients refractory disease infection their outcome. METHODS AND RESULTS: Nine moderate-severe attacks did not respond to i.v. prednisone (1 mg/kg/day) for mean 24 days. Four these were further treated cyclosporine A (4 mg/kg/day)....
Bacterial translocation occurs in ascitic cirrhotic rats, but its association with ascites infection is unknown. The aim of this study was to assess the relation between bacterial and rats. Male Sprague-Dawley rats were induced cirrhosis intragastric CCl4. Ascitic fluid, portal peripheral blood, mesenteric lymph nodes, liver spleen samples cultured before death those less (group A) or more B) than 250 polymorphonuclear neutrophils/mm3 as well healthy control Histological examination jejunum,...
Postoperative recurrence (PR) occurs early after intestinal resection in >75% of Crohn's disease (CD) patients. No well-established strategy for long-term PR prevention is available. The aim was to prospectively evaluate the endoscopic and clinical outcomes postoperative CD on maintenance treatment with azathioprine (AZA), especially patients who developed lesions confined ileocolic anastomosis.Long-term AZA therapy (2-2.5 mg/kg/day) initiated immediately surgery 56 consecutive underwent a...
Aim. The aim was to assess the impact of inflammatory bowel disease (IBD) and its treatment on fertility, pregnancy outcomes, breastfeeding. IBD is a chronic condition that usually diagnosed in young adulthood. Patients are often concerned about fertility outcomes. Methods. A structured questionnaire posted 850 adults with followed-up single center. Results. total 503 patients (59%) median age 40 years equally distributed for gender type returned questionnaire. Overall, 71% had 659 children,...
Summary Background Onset during old age has been reported in upto 10% of total cases inflammatory bowel disease ( IBD ). Aim To evaluate phenotypic characteristics and the use therapeutic resources patients with elderly onset . Methods Case‐control study including all those diagnosed over 60 years since 2000 who were followed‐up for >12 months, identified from databases. Elderly compared aged 18 to 40 at diagnosis, matched by year gender type (adult‐onset). Results One thousand three...
Somatostatin and endoscopic sclerotherapy are widely used in the treatment of acute variceal bleeding. Although objective evidence does exist about advantages either treatment, data comparing both procedures scarce. In order to compare effectiveness safety somatostatin bleeding, 70 consecutive cirrhotic patients suffering from esophageal hemorrhage meeting inclusion criteria were randomly assigned with (35 patients) or patients). No differences age, sex, alcohol intake, etiology cirrhosis...
OBJECTIVE: It has been suggested that, in inflammatory bowel disease, cytomegalovirus behaves the intestine as a nonpathogenic bystander, and even its finding intestinal mucosa unclear clinical relevance. We report our experience with small series of patients refractory disease infection their outcome. METHODS AND RESULTS: Nine moderate-severe attacks did not respond to i.v. prednisone (1 mg/kg/day) for mean 24 days. Four these were further treated cyclosporine A (4 mg/kg/day)....