A5051252422- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Genetic and phenotypic traits in livestock
- Meat and Animal Product Quality
- Molecular Biology Techniques and Applications
- Animal Nutrition and Physiology
- RNA modifications and cancer
- Cancer, Lipids, and Metabolism
- Lipid metabolism and biosynthesis
- Peroxisome Proliferator-Activated Receptors
- Microbial Inactivation Methods
- Medical Research and Treatments
- Cancer Cells and Metastasis
- Proteoglycans and glycosaminoglycans research
- Nanoparticle-Based Drug Delivery
- GDF15 and Related Biomarkers
- Circular RNAs in diseases
- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Advanced Glycation End Products research
- Rabbits: Nutrition, Reproduction, Health
- Trace Elements in Health
- Biochemical effects in animals
- Metabolism, Diabetes, and Cancer
Weifang University of Science and Technology
2015-2023
Shandong Agricultural University
2007-2020
The purpose of this paper was to investigate the effect high-intensity ultrasonication (HIU) pretreatment before enzymolysis on structural conformations walnut protein isolate (WPI) and antioxidant activity its hydrolysates. Aqueous WPI suspensions were subjected ultrasonic processing at different power levels (600-2000 W) times (5-30 min), then changes in particle size, zeta (ζ) potential, structure investigated, hydrolysates determined. size particles aqueous decreased after ultrasound,...
Intramuscular fat (intramuscular fat, IMF) is one of the important traits pork quality. How to reasonably improve intramuscular content most focus researchers. Some possible regulation deposition candidate genes cause attention people. The objective this study was elucidate relationship between peroxisome proliferator-activated receptor γ (PPARγ) and adipose differentiation-related protein (ADRP) mRNA expression (IMF) in muscle tissue three breeds pig: Laiwu (LW), Lulai Black (LL), Large...
The proliferation and differentiation of preadipocytes are regulated by microRNAs (miRNAs), hormones, other factors. This study aimed to investigate the effects miR-331-3p on in addition fatty acid metabolism.Preadipocytes were transfected with mimics, miR-NC, or inhibitor explore its effect cell accumulation. Furthermore, pre-miR-331-3p, pcDNA3.1(+), differentiation.It was observed that could inhibit proliferation. highly expressed during cellular appeared promote process. In addition, dual...
To determine how adipocyte determination and differentiation factor 1 (ADD1), a gene involved in the of pork quality, is regulated Laiwu Large pigs, we used TaqMan fluorescence quantitative real-time polymerase chain reaction (FQ-PCR) to detect differential expression longissimus muscle (fatty) White (lean) pigs.In this study, ADD1 GAPDH cDNA sequences were cloned using T-A cloning assay, clone consistent with those deposited GenBank.Thus, target fragment was successfully recombined into...
摘要: 为了进一步了解和认识 CuZnSOD 基因的结构和功能
To investigate the effect of miR-331-3p on proliferation porcine renal epithelial cells (PK15) and its mechanism, pcDNA 3.1(+) overexpression vector miRNA-331-3p (pcDNA 3.1(+)-miR-331-3p) was constructed. PK15 were divided into four groups, including experimental group, control inhibitor group group. Experimental transfected with 3.1(+)-miR-331-3p 3.1(+), respectively. Inhibitor negative (miR-331-3p NC), Above all, CCK-8 reagent used to plot cell curve Propidium (PI) staining detect...
The proliferation and differentiation of preadipocytes are regulated by microRNAs (miRNAs), hormones other factors. This study aimed to investigate the effects miR-331-3p on proliferationand in addition fatty acid metabolism. data indicated that is a novel regulator cellular differentiation. It was observed capable inhibiting proliferation. Furthermore, highly expressed during andappeared promote process. In addition, dual fluorescein analysis showed dihydrolipoamideS-succinyltransferase...
The proliferation and differentiation of preadipocytes are regulated by microRNAs (miRNAs), hormones other factors. This study aimed to investigate the effects miR-331-3p on proliferationand in addition fatty acid metabolism. data indicated that is a novel regulator cellular differentiation. It was observed capable inhibiting proliferation. Furthermore, highly expressed during andappeared promote process. In addition, dual fluorescein analysis showed dihydrolipoamideS-succinyltransferase...
The tumor microenvironment (TME), which is composed of stomal cells, numerous cytokines and growth factors directly related to poor prognosis, has been proven play an important role in the development breast cancer. Considering that CD44 receptors are over-expressed on surface cancer cells cancer-associated fibroblasts (CAFs), hyaluronic acid (HA)-modified liposomes could simultaneously target them via HA-CD44-mediated endocytosis. In this study, mifepristone (RU486) curcumin (CUR) were...