A5042767927- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Parasites and Host Interactions
- Ecosystem dynamics and resilience
- Mosquito-borne diseases and control
- Helminth infection and control
- Hepatitis Viruses Studies and Epidemiology
- Viral Infections and Vectors
- Transgenic Plants and Applications
- Respiratory and Cough-Related Research
- Herpesvirus Infections and Treatments
- Insects and Parasite Interactions
- Pediatric health and respiratory diseases
- Research on Leishmaniasis Studies
- Parasite Biology and Host Interactions
- Animal Virus Infections Studies
- Virology and Viral Diseases
- Respiratory viral infections research
Children's Hospital of Los Angeles
2022-2023
Saint Louis University
2019-2021
Siriraj Hospital
2016-2020
Mahidol University
2016-2020
McGill University
2016-2018
Beth Israel Deaconess Medical Center
2017
Not all vaccines afford robust protection against ZIKV challenge in rhesus monkeys at 1 year after vaccination.
Schistosomiasis is the most important human helminth infection due to its impact on public health. The clinical manifestations are chronic and significantly decrease an individual's quality of life. Infected individuals suffer from long-term organ pathologies including fibrosis which eventually leads failure. development a vaccine against this parasitic disease would contribute long-lasting in spectrum transmission.Our group has chosen Schistosoma mansoni (Sm) cathepsin B, peptidase involved...
Background: A skin prick test (SPT) and food challenge (OFC) are useful in identification of sensitization allergy.Objective: To evaluate allergen by SPT allergy OFC allergic Thai patients Methods: SPTs for common allergens were performed on at Siriraj Hospital, Bangkok, Thailand, from 2011 to 2015.An was positive with informed consent.Results: 539 (20%) out 2,678 (73.8% < 10 years old).Crab the most sensitized each year study period.In aged 1 year, foods egg white (23.8%) wheat (22.2%),...
A vaccine against schistosomiasis would contribute to a long-lasting decrease in disease spectrum and transmission. Our previous protection studies mice using Schistosoma mansoni Cathepsin B (Sm-Cathepsin B) resulted 59% 60% worm burden reduction with CpG oligodeoxynucleotides Montanide ISA720 VG as adjuvants, respectively. While both formulations significant mouse model of schistosomiasis, the elicited immune responses differed. Therefore, this study, we aimed decipher mechanisms involved...
Background: Flooding may affect aeroallergen sensitization.Objective: To evaluate sensitization in children with asthma and/or allergic rhinitis (AR) by skin prick test (SPT) before and after the great flood of 2011 Bangkok, Thailand. Methods:The study was performed retrospectively AR (aged 0-18 years) Siriraj Hospital, Thailand from 2009 to 2013.All cases received SPT common aeroallergens.Results: SPTs were 2009-2013 a total 2,010 58.2% 60.5% showed positive results,...
Objective The purpose of this study was to evaluate the clinical characteristics allergy stings from Hymenoptera order insects in a hospital Thailand. Methods A descriptive retrospective analytical carried out inpatients and outpatients suffering 2009 2013 Siriraj Hospital. Results Medical records 386 patients with an were evaluated. Anaphylaxis more common younger than 15 years, who comprised 22.3% study. most sting type wasps (58.3%). Eighty-five percent sought medical treatment less 24...
The assessment of erythema in patients with atopic dermatitis (AD) is based on clinical examination. difficulty perceiving Black AD has led to underestimation severity these patients.In this study, we analyzed the concentration skin tape soluble protein lesions against common signs.A total 50 children were included. Skin was extracted from and validated signs, including erythema, excoriation, edema, oozing, lichenification.Concentration positively correlated acute signs AD, especially...
The skin prick test (SPT) is a valid and approved tool that used to diagnose atopic diseases. SPT accurate, safe, simple inexpensive. However, the histamine concentration as positive control in varies among centers.To compare results using different concentrations of locally-prepared imported solutions.This prospective, randomized, double-blind, self-controlled study was performed healthy adult volunteers. 4 solutions (imported, 1 mg/mL; locally-prepared, 1, 5 10 mg/mL). Locally-prepared...
Background: Mold sensitization has been reported as a factor associated with severe asthma exacerbation (SAE).Objective: To identify the factors SAE in asthmatic children, particularly mold sensitization. Methods:The children recruited into this case-control study were classified an and outpatient (OPD) group, based on their histories of hospitalization preceding year.A skin prick test to common aeroallergens was performed.Possible risk analyzed.Results: A total 102 patients enrolled.The 51...
Background: Fire ant, honey bee, and wasp allergen extracts are useful in the diagnosis treatment of severe Hymenoptera allergic patients.Objective: To evaluate result skin prick test (SPT) intradermal (ID) compared between local commercial insect patients with sting allergy.Methods: SPT ID using were performed.Specific IgE (sIgE) to wasp, fire ant; component-resolved (CRD); (rApi m1, rApi m2, m3, m5, m10, rVes v5, rPol d5, v1); and, cross-reactive carbohydrate determinant (CCD)...