- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Virology and Viral Diseases
- Creativity in Education and Neuroscience
- Design Education and Practice
- Biomedical and Engineering Education
- Family and Disability Support Research
- Education and Critical Thinking Development
- Innovative Teaching and Learning Methods
- Education and Technology Integration
- Reformation and Early Modern Christianity
- Race, History, and American Society
- Outdoor and Experiential Education
- Health and Medical Research Impacts
- Team Dynamics and Performance
- Youth Development and Social Support
- Travel Writing and Literature
- Hannah Arendt's Political Philosophy
- Educator Training and Historical Pedagogy
- Child and Adolescent Psychosocial and Emotional Development
- Theology and Philosophy of Evil
- Child Abuse and Trauma
- Cancer Research and Treatments
- Teaching and Learning Programming
- HIV/AIDS drug development and treatment
Utah State University
2023
Beth Israel Deaconess Medical Center
2017-2023
University of Mary Hardin–Baylor
2018
University of Massachusetts Dartmouth
2015-2017
Brigham Young University
2012-2015
Iowa State University
2013
Not all vaccines afford robust protection against ZIKV challenge in rhesus monkeys at 1 year after vaccination.
A novel T cell–based ZIKV vaccine, encoding NS1 protein, confers protection against systemic infection.
In 2015, there was a large outbreak of Zika virus (ZIKV) in Brazil. Despite its relatively mild impact on healthy adults, ZIKV infection during pregnancy has been associated with severe birth defects. Currently, is no vaccine available, but several candidates based the membrane (M) and envelope (Env) structural proteins showed promising results preclinical clinical studies. Here, immunogenicity protective efficacy non-replicating adenoviral vector type 26 (Ad26) that encodes M-Env antigens...
ABSTRACT Human and chimpanzee adenovirus vectors are being developed to circumvent preexisting antibodies against common such as Ad5. However, baseline immunity these still exists in human populations. Traditional cloning of new vaccine is a long cumbersome process that takes 2 months or more requires rare unique restriction enzyme sites. Here we describe novel, enzyme-independent method for rapid reduces the total procedure 1 week. We 14 novel from rhesus monkeys can be grown high titers...
Sustained virologic control of human immunodeficiency virus type 1 (HIV-1) infection after discontinuation antiretroviral therapy (ART) is a major goal the HIV-1 cure field. A recent study reported that administration an antibody against α
With growing interest in supporting the development of computational thinking (CT) early childhood, there is also need for new assessments that serve multiple purposes and uses. In particular, a to understand design formative can be used during classroom instruction provide feedback teachers children real-time. this paper, we report on an empirical study advance unit observational analysis assessment call indicator knowledge refinement opportunity or as shorthand, KRO indicators. We put...
Zika virus (ZIKV) is an emerging pathogen that causes devastating congenital defects. The overlapping epidemiology and immunologic cross-reactivity between ZIKV dengue (DENV) pose complex challenges to vaccine design, given the potential for antibody-dependent enhancement of disease. Therefore, classification ZIKV-specific antibody targets notable value. From a ZIKV-infected rhesus macaque, we identify ZIKV-reactive B cells isolate potent neutralizing monoclonal antibodies (mAbs) with no...
Multiple research studies have examined the role of undergraduate engineering curriculum on students’ innovation capabilities. The majority these used cross-sectional samples to compare students at beginning and end their college careers, most results shown that seniors outperform freshmen. In following paper, we use a combination longitudinal comparisons uncover when capabilities grow. Over two-year period, majors different points in careers completed concept generation tasks. Their...
The goal of the current work was to supplement our existing on creativity with a key design hurdle: fixation. Design fixation measured based six features litter collector that used as physical example for students who were asked ‘next generation collector’. We found certain occurred more commonly than others. If less common present in design, chances greater highly fixated. Across Mechanical Engineering program, mean decreased seniors compared other students. Fixation and originality had an...
Abstract Engaging Freshmen Women in Research – Feedback from Students and Best Practices for Faculty Significant research has been focused on increasing the participation of diverse populations inSTEM fields. Many researchers have specifically examined ways to improve recruitment andretention women engineering. NSF supported indicates that “Women students thatparticipate more frequently support activities are less likely leave engineering than thosewho do not participate or frequently.”...
Vizcaya was originally the private winter residence of industrialist James Deering and in course last century has known many identities. In Vizcaya’s recent process to refresh our mission vision, we wondered: What should role be new vision? Why does he matter? exploring two founding stories – story estate museum envision as a catalyst that enables us embrace people, place, preservation innovation through past, present future. Through this process, redefined its which is inspire cultural...