Medhat Osman

ORCID: 0000-0002-1828-4369
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Radiation Dose and Imaging
  • Advanced Radiotherapy Techniques
  • Medical Imaging and Pathology Studies
  • Advanced X-ray and CT Imaging
  • Radiopharmaceutical Chemistry and Applications
  • Cancer Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Prostate Cancer Treatment and Research
  • Advanced MRI Techniques and Applications
  • Glioma Diagnosis and Treatment
  • Cardiac Imaging and Diagnostics
  • Head and Neck Cancer Studies
  • Lung Cancer Diagnosis and Treatment
  • Building Energy and Comfort Optimization
  • Lung Cancer Treatments and Mutations
  • Lymphoma Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Neuroblastoma Research and Treatments
  • Cardiovascular Disease and Adiposity
  • Adipose Tissue and Metabolism
  • Music Therapy and Health
  • Head and Neck Surgical Oncology
  • Wind and Air Flow Studies

Saint Louis University Hospital
2015-2025

St. Louis VA Medical Center
2011-2025

Elman Retina Group
2025

Saint Louis University
2014-2024

Minia University
2009-2022

Kuwait University
2022

Active Medicine (United Kingdom)
2002-2022

University of Pittsburgh Medical Center
2022

BeiGene (China)
2019

Whakauae Research (New Zealand)
2018

PURPOSE: To retrospectively evaluate the distribution of fluorine 18 fluorodeoxyglucose (FDG) in head and neck region with combined positron emission tomography–computed tomography (PET/CT) patients no known abnormality this region. MATERIALS AND METHODS: The institutional review board allowed a retrospective PET/CT images obtained 78 non–head cancer waived requirement for informed consent. accumulation FDG 11 normal structures was visually quantitatively assessed retrospectively. Positive...

10.1148/radiol.2343030301 article EN Radiology 2005-03-01

TM-601 binds to malignant brain tumor cells with high affinity and does not seem bind normal tissue. Preclinical studies suggest that iodine-131 (131I) -TM-601 may be an effective targeted therapy for the treatment of glioma. We evaluated safety, biodistribution, dosimetry intracavitary-administered 131I-TM-601 in patients recurrent glioma.Eighteen adult (17 glioblastoma multiforme one anaplastic astrocytoma) histologically documented glioma a Karnofsky performance status > or = 60% who were...

10.1200/jco.2005.05.4569 article EN Journal of Clinical Oncology 2006-07-28

The study aims to identify the effect of environmental sustainability accounting (ESA) on competitive advantage (CA), and ESA making decisions (funding, investment, strategic) in Sudanese banking. A questionnaire was used collect data from 135 accountants managers descriptive method confirm that study's goals had been met. is analyzed, hypotheses are tested, using Smart pls application. found a positive relationship between CA banking sector. Additionally, has with funding, strategic Based...

10.5267/j.dsl.2025.1.007 article EN cc-by Decision Science Letters 2025-01-01

10.1007/s00259-002-1055-3 article EN European Journal of Nuclear Medicine and Molecular Imaging 2003-05-01

The aim of this retrospective study was to report the prevalence and patterns soft tissue (ST) metastasis detected with true whole-body (TWB) F-18 FDG PET/CT acquired from top skull through bottom feet compare such findings that typically skull-base upper-thigh, thus limited (LWB) field view (FOV).TWB FDG-PET/CT scans were performed in 500 consecutive cancer patients. Suspected ST verified by correlation surgical pathology, other imaging modalities, or clinical follow-up.Nine out patients...

10.1186/1471-2342-7-8 article EN cc-by BMC Medical Imaging 2007-12-01

SPLASH (NCT04647526) is a multicenter phase III trial evaluating the efficacy and safety of [177Lu]Lu-PNT2002 radioligand therapy in metastatic castration-resistant prostate cancer (mCRPC). This study leveraged lead-in to assess tissue dosimetry evaluate preliminary efficacy, prior expansion into randomized phase. Here we report those results. Enrolled participants had mCRPC that progressed on one androgen receptor pathway inhibitor (ARPI), were prostate-specific membrane antigen (PSMA)...

10.3389/fonc.2024.1483953 article EN cc-by Frontiers in Oncology 2025-01-07

Purpose The aim of this retrospective study was to report the prevalence and imaging characteristics bone metastases detected with F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) and, when possible, compare these findings performance scans in same patients. Methods reports 403 patients histologically proved malignant disease who underwent a PET scan for initial or post-therapeutic staging were reviewed presence possible metastases. Based on final diagnosis confirmed by...

10.1097/01.rlu.0000057556.54046.7a article EN Clinical Nuclear Medicine 2003-04-01

Purpose. We retrospectively compared the maximum standard uptake value (SUVmax) of FDG PET in four different sites to evaluate whether a common diagnostic SUVmax threshold may exist these tumor locations. further postulate that thresholds are higher thoracic lesions than extrathoracic lesions. Material and methods. N = 143 patients subgroups underwent PET/CT: a) 42 for solitary pulmonary nodules (SPNs) characterization with b) respective mediastinal lymph nodes (LNs), c) 65 LN staging head...

10.3109/0284186x.2010.550933 article EN Acta Oncologica 2011-01-19

We evaluated the incidence of synchronous primary malignancies in patients undergoing <sup>68</sup>Ga-labeled prostate-specific membrane antigen PET/CT for prostate cancer (PC). <b>Methods:</b> Reports 764 PC were reviewed. Incidental lesions atypical metastases and suggestive a malignancy identified. Follow-up was obtained to confirm etiology. <b>Results:</b> Lesions found 49 (6.4%) patients, confirmed 5 (0.7%; 2 lung, 1 lymphoma, thyroid, base tongue). In 8 (1.0%), proven be from PC. 24...

10.2967/jnumed.117.190215 article EN Journal of Nuclear Medicine 2017-06-01

The current study characterized pleural changes induced by talc pleurodesis (TP), based on serial positron emission tomography/computer-tomography (PET/CT) with F-18 fluorodeoxyglucose (FDG).A total of 8 cancer patients who had both TP and PET/CT no evidence active involvement after were retrospectively evaluated. Maximum standard uptake values, maximum Hounsfield units (HU), thickness followed over time.The 25 scans performed in an average 22 months TP. An increased FDG was associated...

10.1097/rlu.0b013e3181bece11 article EN Clinical Nuclear Medicine 2009-11-17

Objectives/Hypothesis The role of follow‐up and the detection recurrent or new primary disease in cancer management remains to be defined. Specifically, effectiveness impact on survival imaging studies that detects before it is symptomatic noted exam unknown. Study Design Retrospective chart review. Methods A retrospective review was performed a series head neck patients (n = 123), at single institution from February 18, 2004 July 9, 2007, who had undergone nonstaging 18F‐fluorodeoxyglucose...

10.1002/lary.23941 article EN The Laryngoscope 2013-07-01

This retrospective review was performed to determine whether patients with brown adipose tissue (BAT) detected by fluorine-18-fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) imaging have less central obesity than BMI-matched control without detectable BAT.Thirty-seven adult oncology F-FDG BAT uptake were retrospectively identified from PET/CT studies 2011 2013. The cohort consisted of 74 matched for BMI/sex/season. Tissue fat content estimated CT density (Hounsfield units) a...

10.1097/mnm.0000000000000691 article EN Nuclear Medicine Communications 2017-05-16

Background and aim In a combined positron emission tomography (PET) computed (CT) system, the CT images can be used for attenuation correction as well image fusion. However, quantitative qualitative differences have been reported between based corrected PET conventional transmission scan images. The purpose of this study was to investigate potential in PET/CT caused by bowel due motion. Methods Twelve patients had scans performed using 68Ge methods. Three imaging datasets were generated...

10.1097/00006231-200403000-00002 article EN Nuclear Medicine Communications 2004-03-01
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