A5043999741- Statistical Distribution Estimation and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mitochondrial Function and Pathology
- Statistical Methods and Bayesian Inference
- COVID-19 epidemiological studies
- Advanced Statistical Methods and Models
- Healthcare Policy and Management
- Health and Wellbeing Research
- Statistical Methods and Inference
- RNA modifications and cancer
- Neonatal and fetal brain pathology
- Optimal Experimental Design Methods
- Statistical Methods in Clinical Trials
- Global Cancer Incidence and Screening
- Health disparities and outcomes
- Lung Cancer Diagnosis and Treatment
- Primary Care and Health Outcomes
- Lung Cancer Research Studies
- COVID-19 Pandemic Impacts
- Obesity, Physical Activity, Diet
- Advanced Bandit Algorithms Research
- Metabolism and Genetic Disorders
- Musculoskeletal pain and rehabilitation
- Bayesian Methods and Mixture Models
- Spectroscopy and Chemometric Analyses
The University of Texas Health Science Center at Tyler
2009-2025
The University of Texas at Tyler
2022-2025
Meharry Medical College
2024
Texas State University
2017-2024
Monash Medical Centre
2024
Monash Health
2024
Monash University
2024
University of Toronto
2023
University of Rajasthan
2020-2023
Lovely Professional University
2023
The generalized Poisson regression model has been used to dispersed count data. It is a good competitor the negative binomial when data over-dispersed. Zero-inflated and zero-inflated models have proposed for situations where generating process results into too many zeros. In this paper, we propose (ZIGP) domestic violence with Estimation of parameters using method maximum likelihood provided. A score test presented whether number zeros large adequately fit
Text and structural data mining of web social media (WSM) provides a novel disease surveillance resource can identify online communities for targeted public health communications (PHC) to assure wide dissemination pertinent information. WSM that mention influenza are harvested over 24-week period, 5 October 2008 21 March 2009. Link analysis reveals PHC. is shown trends in flu posts correlate real-world influenza-like illness patient report data. We also bring bear graph-based technique...
Background Resveratrol, a naturally occurring phytopolyphenol compound, has attracted extensive interest in recent years because of its diverse pharmacological characteristics. Although resveratrol possesses chemopreventive properties against several cancers, the molecular mechanisms by which it inhibits cell growth and induces apoptosis have not been clearly understood. The present study was carried out to examine whether PI3K/AKT/FOXO pathway mediates biological effects resveratrol....
We studied the efficacy of osteopathic manual treatment (OMT) and ultrasound therapy (UST) for chronic low back pain.A randomized, double-blind, sham-controlled, 2 × factorial design was used to study OMT UST short-term relief nonspecific pain. The 455 patients were randomized (n = 230) or sham 225) main effects groups, 233) 222) groups. Six sessions provided over 8 weeks. Intention-to-treat analysis performed measure moderate substantial improvements in pain at week 12 (30% greater 50%...
Cancer stem cells (CSCs) play major roles in cancer initiation, progression, and metastasis. It is evident from growing reports that PI3K/Akt/mTOR Sonic Hedgehog (Shh) signaling pathways are aberrantly reactivated pancreatic CSCs. Here, we examined the efficacy of combining NVP-LDE-225 (PI3K/mTOR inhibitor) NVP-BEZ-235 (Smoothened on CSCs characteristics, microRNA regulatory network, tumor growth. co-operated with inhibiting CSC's characteristics growth mice by acting at level Gli....
Ovarian cancer is the second most common gynecological and leading cause of death in United States. In this article we review diagnosis current management epithelial ovarian which accounts for over 95 percent malignancies. We will present various theories about potential origin discuss genetic anomalies syndromes that may cancers with emphasis on Breast type 1/2 mutations. The pathology pathogenesis carcinoma also be presented. Lastly, provide a comprehensive overview treatment strategies...
Background Resveratrol (3, 4′, 5 tri-hydroxystilbene), a naturally occurring polyphenol, exhibits anti-inflammatory, antioxidant, cardioprotective and antitumor activities. We have recently shown that resveratrol can enhance the apoptosis-inducing potential of TRAIL in prostate cancer cells through multiple mechanisms vitro. Therefore, present study was designed to validate whether xenograft model cancer. Methodology/Principal Findings alone inhibited growth PC-3 xenografts nude mice by...
MicroRNAs (miRNA) have potential prognostic value for colorectal cancers; however, their based on patient race/ethnicity and pathologic stage has not been determined. The goal was to ascertain the of 5 miRNAs with increased expression in cancers African American (black) non-Hispanic Caucasian (white) patients.TaqMan quantitative real-time PCR used quantify miR-20a, miR-21, miR-106a, miR-181b, miR-203 paired normal tumor cancer archival tissues collected from 106 black 239 white patients....
The objective of the study was to measure risk death due COVID-19 in relation individuals' characteristics, and severity their disease during dominant periods Alpha, Delta, Omicron variants have influenced mortality rates.
The purpose of this study was to investigate the association between Attention Deficit/Hyperactivity Disorder (ADHD) and various factors using a representative sample US children in comprehensive manner. This includes variables that have not been previously studied such as watching TV/playing video games, computer usage, family member's smoking, participation sports.This cross-sectional 68,634 children, 5-17 years old, from National Survey Children's Health (NSCH, 2007-2008). We performed...
N-Myc Interactor is an inducible protein whose expression compromised in advanced stage breast cancer. Downregulation of NMI, a gatekeeper epithelial phenotype, tumors promotes mesenchymal, invasive and metastatic phenotype the cancer cells. Thus mechanisms that regulate NMI are potential interest for understanding etiology tumor progression metastasis. Web based prediction algorithms were used to identify miRNAs potentially target transcript. Luciferase reporter assays western blot analysis...
BACKGROUND: Currently in the U.S. it is recommended that tuberculosis screening and treatment programs be targeted at high-risk populations. While a strategy of testing persons most likely to develop attractive, uncertain how best accomplish this goal. In study we seek identify geographical areas where on-going transmission occurring by linking Geographic Information Systems (GIS) technology with molecular surveillance. METHODS: This cross-sectional analysis was performed on data collected...
Fibromyalgia (FM), one of the most common musculoskeletal disorders, is associated with high levels impaired health and inadequate or limited symptom relief. The cause this complex syndrome unknown, there no known cure. Numerous research results indicate that a combination physical exercise mind-body therapy effective in management. T'ai Chi, an ancient Chinese exercise, combines mindbody therapy.To investigate effects Chi on FM symptoms health-related quality life.Pilot study, group...
The purpose of this study was to determine the prevalence high blood pressure (HBP) and associated risk factors in school children 8 13 years age.Elementary (n = 1,066) were examined. Associations between HBP, body mass index (BMI), gender, ethnicity, acanthosis nigricans (AN) investigated using a based cross-sectional study. Blood measured 95th percentile used HBP. Comparisons with without HBP utilized. crude multiple logistic regression adjusted odds ratios as measures association.Females,...
The adoption of health information technology has been recommended as a viable mechanism for improving quality care and patient outcomes. However, the capacity (i.e., availability use multiple advanced functionalities), particularly in federally qualified centers (FQHCs) on is not well understood. We examined associations between (HIT) at FQHCs care, measured by receipt discharge summary, frequency patients receiving reminders/notifications preventive care/follow-up timely appointment...
Rationale: Physical inactivity among patients with chronic obstructive pulmonary disease is associated exacerbations requiring high-cost health care utilization including urgent, emergent, and hospital care.Objectives: To examine the effectiveness of a behavioral lifestyle physical activity intervention combined self-management education to prevent utilization.Methods: This was an analysis secondary outcomes Chronic Obstructive Pulmonary Disease Self-Management Activation Research Trial,...
The goal of this study was to understand the role altered mitochondrial function in breast cancer progression and determine potential molecular alteration signature developing exosome-based biomarkers.This designed characterize critical components regulating tumorigenesis. Experiments were conducted assess these molecules for biomarker development.We observed a remarkable reduction spontaneous metastases through interplay mitochondria by SH3GL2, vesicular endocytosis-associated protein MFN2,...