Juan Chen

ORCID: 0000-0002-1844-0042
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Research Areas
  • Electrochemical sensors and biosensors
  • Catalytic Processes in Materials Science
  • Metal-Organic Frameworks: Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Advanced Nanomaterials in Catalysis
  • Advanced Photocatalysis Techniques
  • Food Quality and Safety Studies
  • Enzyme Catalysis and Immobilization
  • Analytical chemistry methods development
  • Traditional Chinese Medicine Analysis
  • Molecular Sensors and Ion Detection
  • Nanomaterials for catalytic reactions
  • Phytochemistry and Biological Activities
  • Conducting polymers and applications
  • Berberine and alkaloids research
  • Carbon and Quantum Dots Applications
  • Fuel Cells and Related Materials
  • Polymer Nanocomposites and Properties
  • Pharmacological Effects of Natural Compounds
  • Chromatography in Natural Products
  • Electrocatalysts for Energy Conversion
  • Computational Drug Discovery Methods
  • Medicinal Plants and Neuroprotection
  • Analytical Chemistry and Sensors
  • Plant-based Medicinal Research

Hunan Institute of Science and Technology
2025

University of Science and Technology Beijing
2021-2025

Lanzhou University
2004-2025

Deleted Institution
2024

Chinese Academy of Sciences
2004-2024

Beijing National Laboratory for Molecular Sciences
2024

Institute of Chemistry
2024

University of Chinese Academy of Sciences
2010-2024

Shanghai Jiao Tong University
2022

Shanghai Research Institute of Materials
2022

Water-soluble cupric oxide nanoparticles are fabricated via a quick-precipitation method and used as peroxidase mimetics for ultrasensitive detection of hydrogen peroxide glucose. The water-soluble CuO show much higher catalytic activity than that commercial due to their affinity peroxide. In addition, the as-prepared stable over wide range pH temperature. This excellent stability in form aqueous colloidal suspensions makes application easier systems. A colorimetric assay glucose has been...

10.1039/c2an35072f article EN The Analyst 2012-01-01

It′s a mummers catalyst: Upon the addition of cupric oxide nanoparticles to peroxidase substrate TMB in presence H2O2, blue color product can be formed with maximum absorbance at λ=652 nm, indicating that have peroxidase-like catalytic activity. Detailed facts importance specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors. Please note: The publisher is responsible for content...

10.1002/cctc.201100064 article EN ChemCatChem 2011-06-07

Objective: To evaluate the potential of hyaluronic acid (HA)-coated bovine serum albumin nanoparticles (BSANPs) as a novel chondrocyte-targeting drug-delivery nanomedicine. Methods: The HA-BSANPs were characterized by dynamic light scattering, transmission electron microscopy, differential scanning calorimetry, and X-ray diffraction. Fluorescence imaging was used to visualize distribution after intra-articular injection. efficiency cellular uptake mechanism investigated using endocytic...

10.2147/ijn.s50721 article EN cc-by-nc International Journal of Nanomedicine 2013-10-01

The development of low-cost, highly efficient, and durable non-noble metal catalysts for hydrogenation reactions has long posed a significant challenge in the field catalysis. In this study, we present novel catalyst, Ni/La NPs@UD, which consists ultra-small nickel nanoparticles (NPs) modified with lanthanum (La) species anchored on defective UiO-66 supports, specifically designed dicyclopentadiene (DCPD). incorporation La not only enhances electronic properties Ni centers but also...

10.2139/ssrn.5091855 preprint EN 2025-01-01

The high-temperature proton exchange membranes suffer from weak binding strength for phosphoric acid molecules, which seriously reduce the fuel cell efficiency, especially operation stability. Introduction of microporous material in membrane can effectively leaching acid. However, due to poor compatibility between polymer and fillers, membrane's performance significantly reduced at high fillers content. Therefore, this work, strategy micropore confinement was developed; β-cyclodextrin...

10.1021/acs.langmuir.4c04624 article EN Langmuir 2025-01-16

Enzyme inhibition-based drug screening is a critical strategy in development. However, significant limitations arise from the instability, limited reusability, and narrow applicability of traditional enzyme assays when for inhibitors complex matrices, such as extracts Chinese medicines (TCMs). A was developed that combines capillary electrophoresis (CE) with an enzymatic assay utilizing covalently immobilized α-glucosidase (α-Glu). NH2-MIL-53(Al) synthesized using hydrothermal method,...

10.1021/acs.langmuir.4c05114 article EN Langmuir 2025-02-09

Fluorescent probes based on boron dipyrromethene functionalized with a phenylboronic acid group (BODIPY–PBAs) were synthesized in high yield for the first time by Suzuki coupling of bis(pinacolato)diboron and 8-(4-bromophenyl)-1,3,5,7-tetramethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY). Wavelength tuning fluorophores was achieved attaching an auxochromic substituent to 5-position BODIPY core structure through Knoevenagel condensation. The emission intensity increases when binding...

10.1021/ac301456s article EN Analytical Chemistry 2012-11-16

ABSTRACT Amphiphilic methyl cellulose (MC) was used as the emulsifier and internal wall material to increase microencapsulation efficiency (ME) of tea tree oil (TTO) stability emulsion for spray‐drying. The results microscopy images, zeta potential, indicated that components affected morphology, stability, ME microcapsules. microcapsules with materials MC/chitosan (CTS)/alginate (ALG) were spherical had higher than those monocomponent or bicomponents MC, CTS, ALG, triple MC/ALG/CTS. Spray...

10.1002/app.44662 article EN Journal of Applied Polymer Science 2016-11-30

The technology based on immobilized enzymes was employed to screen the constituents inhibiting disease-related enzyme activity from traditional Chinese medicine, which is expected become an important approach of innovative drug development. Herein, Fe3O4@POP composite with a core–shell structure constructed for first time Fe3O4 magnetic nanoparticles as core, 1,3,5-tris (4-aminophenyl) benzene (TAPB) and 2,5-divinylterephthalaldehyde (DVA) organic monomers, used support immobilizing...

10.1021/acs.langmuir.2c02979 article EN Langmuir 2023-04-04
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