Jun Yoshikawa

ORCID: 0000-0002-1882-9701
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease and Transplantation
  • Semiconductor materials and devices
  • Organ Transplantation Techniques and Outcomes
  • Microbial Metabolites in Food Biotechnology
  • Medical Imaging and Pathology Studies
  • Enzyme Production and Characterization
  • Cardiac Valve Diseases and Treatments
  • Biofuel production and bioconversion
  • Intracranial Aneurysms: Treatment and Complications
  • Cardiac Imaging and Diagnostics
  • MRI in cancer diagnosis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Silicon and Solar Cell Technologies
  • Cardiovascular Function and Risk Factors
  • Advanced ceramic materials synthesis
  • Plasma Diagnostics and Applications
  • Cardiac tumors and thrombi
  • Congenital Heart Disease Studies
  • Semiconductor materials and interfaces
  • Epilepsy research and treatment
  • Smart Grid Energy Management
  • Metal and Thin Film Mechanics

Tokyo University of Agriculture
2020-2024

Fukui Prefectural Hospital
2001-2024

Hyogo Brain and Heart Center
2020

Waseda University
2015-2017

Japan Science and Technology Agency
2016

Tokyo Electron (Japan)
2013-2015

National Institute of Advanced Industrial Science and Technology
2007-2013

Toshiba (Japan)
1995-2012

Chiba University
2001-2012

University of Illinois Urbana-Champaign
2008-2010

The blood supplies of nodular lesions associated with liver cirrhosis were analyzed in vivo various imaging modalities. portal supply was evaluated computed tomography (CT) during arterial portography (CTAP); the hepatic angiography, CT following intraarterial injection iodized oil, or ultrasound carbon dioxide microbubbles. A total 84 surgically confirmed hepatocellular carcinomas (HCCs) (less than equal to 3 cm) and 25 areas adenomatous hyperplasia (AH) included study. At CTAP, a seen 96%...

10.1148/radiology.178.2.1846240 article EN Radiology 1991-02-01

The purpose of this study is to evaluate the correlation between intranodular blood supply revealed by CT during intraarterial injection contrast medium, mainly using helical CT, and grade malignancy hepatocellular nodules associated with liver cirrhosis as classified International Working Party World Congress Gastroenterology.We studied 201 histologically proven (101 resected 100 biopsied nodules), including 47 low-grade dysplastic (low-DNs), 56 high-grade (high-DNs), 24 well-differentiated...

10.2214/ajr.172.4.10587130 article EN American Journal of Roentgenology 1999-04-01

To assess the hemodynamics and main drainage vessel of hypervascular hepatocellular carcinoma.Single-level dynamic computed tomography during hepatic arteriography (CTHA) was performed in 32 patients with carcinoma. Carcinoma confirmed histologic (n = 9) or clinical 23) examination results. Single-level CTHA findings were retrospectively analyzed. Histologic specimens from 40 livers carcinoma also examined, special attention to vessels along rim lesion.Contrast material enhancement on...

10.1148/radiology.206.1.9423667 article EN Radiology 1998-01-01

Differentiation of hepatocellular carcinomas from adenomatous hyperplastic nodules (AHNs) is important for the early and precise detection carcinoma in cirrhotic liver. For this purpose, authors compared findings on magnetic resonance (MR) images surgically resected AHNs (n = 7) with those 47). were divided into two histologic groups: without atypia 5) atypical hepatocytes or malignant foci 2). All hyperintense T1-weighted spin-echo hypointense T2-weighted relative to surrounding However,...

10.1148/radiology.173.1.2550995 article EN Radiology 1989-10-01

To analyze the correlation between pseudolesions seen in segment IV of liver and aberrant gastric venous drainage (AGVD).Twenty-two patients with a pseudolesion posterior edge (group A) 100 randomly selected without B) underwent computed tomography during arterial portography (CTAP) hepatic arteriography. The frequency visualization AGVD to was compared for groups A B.AGVD at arteriography 18 22 group A. None B had AGVD. difference angiographically visible statistically significant (chi 2...

10.1148/radiology.193.1.8090916 article EN Radiology 1994-10-01

PURPOSE: To compare the efficacy of fat-suppressed T1-weighted magnetic resonance (MR) imaging and dynamic MR in diagnosis small pancreatic adenocarcinomas. MATERIALS AND METHODS: Pancreatic adenocarcinomas 15 patients were evaluated with computed tomography (CT) five sequences that included technique multiplanar gradient-recalled acquisition steady state technique. RESULTS: The difference contrast-to-noise ratios between tumor normal pancreas was significantly different (P < .05) used. In...

10.1148/radiology.193.3.7972808 article EN Radiology 1994-12-01

One of the most common sites focal sparing in fatty livers (focal spared area) shown by sonography or CT is posterior edge segment IV. The differentiation such a area from tumor has been diagnostic challenge. purpose this study was to determine if correlation exists between at IV liver and decrease portal perfusion main vein due aberrant gastric venous drainage directed into IV.Seventeen patients with diagnosed on basis sonographic findings who had hepatic arteriography and/or during...

10.2214/ajr.164.5.7717220 article EN American Journal of Roentgenology 1995-05-01

Fatty metamorphosis in hepatocellular carcinoma: radiologic features 10 casesJ Yoshikawa, O Matsui, T Takashima, M Ida, Takanaka, I Kawamura, K Kakuda and S MiyataAudio Available | Share

10.2214/ajr.151.4.717 article ID American Journal of Roentgenology 1988-10-01

We report a histological analysis of the areas high density in postequilibrium and delayed phase CT 43 focal hepatic lesions. The cases consisted 16 cholangiocellular carcinomas, 9 hepatocellular carcinomas (including sclerosing type carcinoma combined hepatocellular-cholangiocellular carcinoma), 13 metastases, 2 granulomas, an inflammatory pseudotumor, malignant lymphoma, epithelioid hemangioendothelioma. Computed tomography was performed after angiography using 40–50 g iodine...

10.1097/00004728-199203000-00006 article EN Journal of Computer Assisted Tomography 1992-03-01

A matured megakaryocyte releases thousands of platelets through a drastic morphological change, proplatelet formation (PPF). The megakaryocyte/erythrocyte-specific transcription factor, p45 NF-E2, is essential for initiating PPF, but the factor regulating PPF has not been identified. Here we report that estradiol synthesized in megakaryocytes triggers PPF. We demonstrate key enzyme steroid hormone biosynthesis, 3beta-hydroxysteroid dehydrogenase (3beta-HSD), target and rescues...

10.1101/gad.1128003 article EN Genes & Development 2003-12-01

Focal fatty change of the liver adjacent to falciform ligament: CT and sonographic findings in five surgically confirmed casesJ Yoshikawa, O Matsui, T Takashima, H Sugiura, K Katayama, Y Nishida M TsujiAudio Available | Share

10.2214/ajr.149.3.491 article EN American Journal of Roentgenology 1987-09-01

Measurement of the pituitary height was performed on magnetic resonance (MR) images 213 subjects with no known or suspected and/or hypothalamic disorders. Midsagittal, T1-weighted were used for measurements and mean heights in each age sex group obtained. In 10 to 69 year range, greater females than males. The groups 0–9 years both genders showed minimum maximum themean observed 19 genders. gradually decreased increasing after 20 years. There a ≥9.0 mm ≥8.0 marked discrepancy between MR...

10.1097/00004728-199001000-00006 article EN Journal of Computer Assisted Tomography 1990-01-01

Ciliated hepatic foregut cysts (CHFCs) are solitary unilocular in the liver that histologically similar to bronchogenic cysts. Three cases of CHFC reported demonstrated radiologic features those solid masses. All lesions were smaller than 3 cm diameter and subcapsular. At ultrasonography, one lesion appeared anechoic but other two hypoechoic. Unenhanced computed tomography be hyperattenuating or isoattenuating relative surrounding parenchyma, no enhanced with administration contrast...

10.1148/radiology.175.2.2183286 article EN Radiology 1990-05-01

The frequency and degree of intrahepatic periportal abnormal intensity (PAI) on magnetic resonance images in patients with or without various hepatobiliary pancreatic diseases were analyzed. In 63 disease, except for a small metastatic liver tumor cavernous hemangioma, no definite PAI was seen. Definite seen all obstructive jaundice, cholangitis, cholangiocellular carcinoma. It also clearly four cases malignant lymphadenopathy the hepatoduodenal ligament, one two acute hepatitis, 47...

10.1148/radiology.171.2.2704798 article EN Radiology 1989-05-01

At least five types of beta-fructofuranosidases (FFases I, II, III, IV and V) were found in the cell wall Aureobasidium pullulans DSM2404 grown a sucrose medium. The fungus first catalyzed transfructosylation sucrose, produced fructooligosaccharide (FOS) glucose culture. FOS was then consumed together with glucose, finally fructose produced. In FOS-producing period, expressed FFase I as dominant FFase. However, FOS-degrading levels FFases V increased. ratios transfructosylating activity to...

10.1111/j.1574-6968.2006.00488.x article EN FEMS Microbiology Letters 2006-10-18

Alphaproteobacterium strain Q-1 is able to oxidize iodide (I(-)) molecular iodine (I(2)) by an oxidase-like enzyme. One of the two isoforms iodide-oxidizing enzyme (IOE-II) produced this was excised from a native polyacrylamide gel, eluted, and purified. IOE-II appeared as single band (51 kDa) showed significant in-gel activity in sodium dodecyl sulfate-polyacrylamide gel electrophoresis without heat treatment. However, at least bands with much higher masses (150 230 were observed treatment...

10.1128/aem.00084-12 article EN Applied and Environmental Microbiology 2012-03-24

Purpose: The purpose of our study was to assess the efficacy single-level dynamic CT during hepatic arteriography (D-CTA) in differentiation between hypervascular hepatocellular carcinoma (HCC) and pseudolesion. Method: D-CTA performed nine cases with HCC Findings on were retrospectively analyzed. Results: transition stain pseudolesion divided into three phases: (1) inflow contrast material portal vein within lesion, (2) lesion staining, (3) fading out stain; that four CM tumor, tumor...

10.1097/00004728-199809000-00006 article EN Journal of Computer Assisted Tomography 1998-09-01

PURPOSE: To clarify the correlation between aberrant gastric venous drainage and a focal spared area at posterior edge of segment IV in fatty liver by using color Doppler ultrasound (US). MATERIALS AND METHODS: Seventeen patients with were examined gray-scale, Doppler, power US. In one patient area, arteriography computed tomography (CT) performed during injection contrast medium into right artery. RESULTS: Focal areas shown five 17 patients. all was observed Power US depicted more clearly...

10.1148/radiology.203.2.9114105 article EN Radiology 1997-05-01
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