A5001179887- Fibromyalgia and Chronic Fatigue Syndrome Research
- Ethnobotanical and Medicinal Plants Studies
- Exercise and Physiological Responses
- Testicular diseases and treatments
- Thermoregulation and physiological responses
- Computational Drug Discovery Methods
- Phytochemistry and Bioactive Compounds
- Biochemical and Structural Characterization
- Plant Gene Expression Analysis
- Ubiquitin and proteasome pathways
- Photosynthetic Processes and Mechanisms
- Essential Oils and Antimicrobial Activity
- Click Chemistry and Applications
- Plant Molecular Biology Research
- Immunotherapy and Immune Responses
Queensland University of Technology
2021-2025
University of Colombo
2017
University of Genoa
2005
Understanding and predicting individual responses to common stressors is essential for optimising performance in high-stress environments. This article outlines a protocol study identify biomarkers that predict under heat, musculoskeletal, psychosocial sleep stress, future integration into wearable sensor system. In Phase I, healthy adults aged between 18 45 years (n=104) will be recruited an intervention trial involves exposure one of the four stressors: or deprivation. Biomarkers...
PIASx belongs to the PIAS protein family, members of which modulate activities several transcription factors and act as E3 ligases in sumoylation pathway. The gene is highly expressed testis, suggesting a role spermatogenesis. To investigate function vivo , we have disrupted mice. Interestingly, knockout mice were viable fertile. Despite normal fertility, testis weight mutant animals was reduced their number apoptotic testicular cells increased. Also, sperm count tended be reduced, but...
(1) Background: Rapidly increasing antibiotic resistance is one of the greatest threats to global health, affecting individuals regardless age. Medicinal plants are widely used in traditional medicine prevent and attenuate infectious conditions with minimal adverse effects. However, only a few have been phytochemically investigated for their medicinal properties subsequent biological activities. Syncarpia hillii, plant traditionally by Indigenous Australians treat sores, wounds, skin...
The promoter region of a drought and abscisic acid (ABA) inducible gene, osr40c1, was isolated from salt-tolerant indica rice variety Pokkali, which is 670 bp upstream the putative translation start codon. In silico analysis resulted sequence showed that at least 15 types motifs were distributed within sequence, including two common elements, TATA CAAT boxes. Additionally, several cis-acing regulatory elements may be involved in regulation osr40c1 expression under different conditions found...
Abstract A virtual screening approach based upon a combination of docking and pharmacophore methods was utilized on library 1.4 million molecules to identify novel antimicrobial agents, which may potentially act via inhibition the caseinolytic protease. Using this method, compound 6 found be bactericidal against three staphylococcal species (minimum inhibitory concentration (MIC)=4–16 μg/mL). Further, subsequent structural optimization led identification 24, shown most potent analog within...