A5091108366- Sleep and related disorders
- Early Childhood Education and Development
- Infant Development and Preterm Care
- Traumatic Brain Injury Research
- Youth Substance Use and School Attendance
- Obesity, Physical Activity, Diet
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Sleep and Work-Related Fatigue
- Sleep and Wakefulness Research
- Impact of Light on Environment and Health
- Neuroscience of respiration and sleep
- Pediatric health and respiratory diseases
- Children's Physical and Motor Development
- Infant Health and Development
- Educational and Psychological Assessments
- Homelessness and Social Issues
- Child and Adolescent Psychosocial and Emotional Development
- Family and Disability Support Research
- S100 Proteins and Annexins
- Kawasaki Disease and Coronary Complications
- Heart Rate Variability and Autonomic Control
- School Health and Nursing Education
- Youth Education and Societal Dynamics
- Child Development and Digital Technology
The University of Queensland
2018-2025
ARC Centre of Excellence for Children and Families over the Life Course
2021-2024
Australian Research Council
2023-2024
ARC Centre of Excellence for the Digital Child
2023-2024
UNSW Sydney
2023
National Institutes of Health
2018-2022
National Institute of Nursing Research
2018-2022
In-Q-Tel
2021
Weyerhauser (Canada)
2019
Queensland University of Technology
2014-2019
Understanding and predicting individual responses to common stressors is essential for optimising performance in high-stress environments. This article outlines a protocol study identify biomarkers that predict under heat, musculoskeletal, psychosocial sleep stress, future integration into wearable sensor system. In Phase I, healthy adults aged between 18 45 years (n=104) will be recruited an intervention trial involves exposure one of the four stressors: or deprivation. Biomarkers...
Introduction: Elevated levels of blood-based proinflammatory cytokines are linked to acute moderate severe traumatic brain injuries (TBIs), yet less is known in mild (m)TBI cohorts. The current study examined whether can differentiate patients with mTBI, and without neuroimaging findings (CT MRI). Material Methods: Within 24 h a determined by Glasgow Coma Scale (GCS) between 13 15, participants (n = 250) underwent computed tomography (CT) magnetic resonance imaging (MRI) scan provided blood...
Identifying plasma biomarkers associated with the amount of time an athlete may need before they return to sport (RTS) following a sport-related concussion (SRC) is important because it help improve health and safety athletes.To examine whether can differentiate collegiate athletes who RTS in less than 14 days or more SRC.This multicenter prospective diagnostic study, conducted by National Collegiate Athletics Association-Department Defense Concussion Assessment, Research, Education...
Traumatic brain injury (TBI) is linked to long-term symptoms in a sub-set of patients who sustain an injury, but this risk not universal, leading us and others question the nature individual variability recovery trajectories. Extracellular vesicles (EVs) are promising, novel avenue identify blood-based biomarkers for TBI. Here, our aim was determine if glial fibrillary acidic protein (GFAP) neurofilament light (NfL) measured 1-year postinjury EVs could distinguish from controls, whether...
To understand the relationships between traumatic brain injury (TBI), blood biomarkers, and symptoms of posttraumatic stress disorder (PTSD), depression, postconcussive syndrome symptoms.Cross-sectional cohort study using multivariate analyses.One hundred nine military personnel veterans, both with without a history TBI.PTSD Checklist-Civilian Version (PCL-C); Neurobehavioral Symptom Inventory (NSI); Ohio State University TBI Identification Method; Patient Health Questionnaire-9 (PHQ-9);...
Abstract Background Concussion is the most common type of TBI, yet reliable objective measures related to these injuries and associated recovery processes remain elusive, especially in military personnel. The purpose this study was characterize relationship between cytokines from acute brain injury active duty service members. Inflammatory (IL-6, IL-10, TNFα) were measured acutely blood samples within 8 h following a medically diagnosed concussion then 24 later. Methods Participants ( n =...
Driver fatigue significantly impairs performance and is a major risk factor for road crashes. However, difficult to objectively measure quantify. This study aimed elucidate associations between heart rate variability (HRV) metrics multidimensional construct encompassing objective subjective measures in young drivers with self-reported short sleep. Eighty-four adults underwent assessments during simulated driving. HRV indices RMSSD LF/HF ratio were derived from an electrocardiogram, while...
To examine the relationship between mandatory naptimes in child care and children's nighttime sleep duration, both concurrently 12 months later once school.A sample of 168 children (50-72 months; 55% males) attending licensed centers were observed across their morning throughout scheduled naptime. Mandatory naptime was determined as period which not permitted any alternative activity except lying on bed. Teachers reported each child's napping care. Nighttime total duration by parents at 2...
The timing, intensity, and duration of exposure to both artificial natural light have acute metabolic physiological effects in mammals. Recent research human adults suggests moderate intensity later the day is concurrently associated with increased body mass; however, no studies investigated effect on mass young children. We examined objectively measured 48 preschool-aged children at baseline, their again 12 months later. At earlier was index (BMI). Increased baseline predicted BMI 12-months...
Policy provision for naps is typical in child care settings, but there variability the practices employed. One practice that might modify children's early sleep patterns allocation of a mandatory nap time which all children are required to lie on their beds without alternate activity permitted. There currently limited evidence effects such napping patterns. This study examined association between duration times and group-level settings. Observations were undertaken community sample 113...
Mild traumatic brain injuries (mTBI) are a pervasive concern for military personnel. Determining the impact of injury severity, including loss consciousness (LOC) may provide important insights into risk psychological symptoms and inflammation commonly witnessed in personnel veterans following mTBI. US were categorized three groups; TBI with LOC (n = 36), without 25), Controls 82). Participants reported their history mTBI, (post-traumatic stress disorder [PTSD] depression), health-related...
Mild traumatic brain injury (TBI) is associated with persistent sleep-wake dysfunction, including insomnia and circadian rhythm disruption, which can exacerbate functional outcomes mood, pain, quality of life. Present therapies to treat disturbances in those TBI (e.g., cognitive behavioral therapy for insomnia) are limited by marginal efficacy, poor patient acceptability, and/or high patient/provider burden. Thus, this study aimed assess the feasibility preliminary efficacy morning bright...
Abstract Concurrent mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) are common in U.S. military service members veterans. Tau amyloid‐beta‐42 (Aβ42) proteins that have been linked to cognitive impairment, neurological hallmarks of Alzheimer's disease, may also relate recovery from mTBI. However, the role these maintenance or resolution chronic symptoms has not yet determined. Participants current study were 102 veterans who had sustained an mTBI ( n = 84) injured...
This study examined whether sleep disturbances were associated with neurobehavioral outcome following a traumatic brain injury (TBI) in well characterized group of service members and veterans.Six hundred six participants enrolled into the Defense Veterans Brain Injury Center, 15-Year Longitudinal TBI study. All completed battery tests measuring self-reported disturbances, symptoms, posttraumatic stress disorder symptoms. Data analyzed using analysis variance post hoc comparisons. Four...
BackgroundRoad trauma is a leading cause of death and disability for young Australians (15–24 years). Young adults are overrepresented in crashes due to sleepiness, with two-thirds their fatal attributed sleepy driving. This trial aims examine the effectiveness sleep extension education program improved road safety adults.MethodsYoung aged 18–24 years (n = 210) will be recruited pragmatic randomised controlled employing placebo-controlled, parallel-groups design. The intervention group...
Posttraumatic stress disorder (PTSD) is a common condition for military personnel and veterans. PTSD has been shown to impact gene expression, however, date no study examined comorbid conditions which may also example, excessive daytime sleepiness (EDS). As such, this sought examine expression using RNA sequencing across three group comparisons of veterans: (1) with EDS (PTSDwEDS) versus without (PTSDw/outEDS), (2) Controls (no or EDS) PTSDwEDS, (3) PTSDw/outEDS. We performed experimental...