A5100724231- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Antioxidant Activity and Oxidative Stress
- Immune Response and Inflammation
- Diet and metabolism studies
- Fatty Acid Research and Health
- Health and Lifestyle Studies
- Ubiquitin and proteasome pathways
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Toxin Mechanisms and Immunotoxins
- interferon and immune responses
- Cancer-related molecular mechanisms research
- Influenza Virus Research Studies
- Food Allergy and Anaphylaxis Research
- Immune cells in cancer
- ATP Synthase and ATPases Research
- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Physical Activity and Health
- Folate and B Vitamins Research
- Lipid metabolism and biosynthesis
- Epigenetics and DNA Methylation
- Tryptophan and brain disorders
California Baptist University
2015-2023
Shenzhen Third People’s Hospital
2020
Yale University
2013-2015
University of Health and Allied Sciences
2015
Riverside
2015
Background & AimsEpidemiological and animal studies have indicated an inverse correlation between the rising prevalence of obesity metabolic syndrome exposure to helminths. Whether helminth-induced immune response contributes microbiota remodeling in remains unknown. The aim this study is explore immune-regulatory role helminth prevention HFD-induced through gut microbiome.MethodsC57BL/6J WT STAT6-/- mice were infected with Heligmosomoides polygyrus followed by high fat diet (HFD) feeding...
Regulation of microbially induced cytokine secretion is critical in intestinal immune homeostasis. NOD2, the Crohn's disease-associated bacterial peptidoglycan sensor, activates NF-κB pathway. After chronic NOD2 stimulation human macrophages, significantly attenuated, similar to situation environment. We find that NF-κB1 (p105/p50) expression upregulated with and required for attenuation vitro macrophages vivo mice. Upon stimulation, regulation both activating (H3K4Me2 H4Ac) inhibitory...
Echinacea purpurea is an indigenous North American purple cone flower used by Americans for treatment of various infectious diseases and wounds. This study investigated the effect polysaccharide enriched extract (EE) on polarization macrophages. The results showed that 100 µg/mL EE could markedly activate macrophage increasing expression CD80, CD86, MHCII molecules. Meanwhile, upregulated markers classically activated macrophages (M1) such as CCR7 production IL-1β, IL-6, IL-12p70, TNF-αand...
Proper regulation of microbial-induced cytokines is critical to intestinal immune homeostasis. Acute stimulation nucleotide-binding oligomerization domain 2 (NOD2), the Crohn's disease-associated sensor bacterial peptidoglycan, induces cytokines. However, chronic NOD2 in macrophages decreases upon pattern recognition receptor (PRR) restimulation; cytokine attenuation PRR similarly observed macrophages. The role for transcriptional repressors Twist1 and Twist2 regulating PRR-induced outcomes...
Heterogeneous nuclear ribonucleoprotein I (HNRNP I) is an RNA-binding protein essential for neonatal immune adaptation by downregulating interleukin-1 receptor-associated kinase (IRAK1) in toll-like receptor (TLR)-mediated NF-κB signaling pathways. TLR-mediated associated with chronic inflammation, including the development of inflammatory bowel diseases. Therefore, dietary intake one major concerns individuals The present study aims to investigate effects a protein-enriched diet on...
SUMOylation (the process of adding the SUMO [small ubiquitin-like modifier] to substrates) is an important post-translational modification critical proteins in multiple processes. The kinetics parameters pre-SUMO1-3 by its protease SENP2 determined a quantitative FRET assay real time.
<span lang="EN-US">The prevalence of obesity among adolescent minority populations has been long recognized, but little research done on Native Americans adolescents. Using anthropometric measurements and dietary assessments, the findings within each study have shown to obtain baseline measures determine Sherman Indian High School’s American population. Data assessment appear be use for predicting creating effective future interventions. Compiling data using Harvard School Public...
Antioxidants are well known for possessing anti-inflammatory properties, which can reduce the risk of chronic disease and obesity. However, very little research has been done to examine antioxidant intake among adolescent minority populations such as Native American adolescents. Our study examined significance adolescents at an urban residential high school in Southern California. population consisted 183 male female adolescents, 14-18 years age, representing 43 tribes from across United...
Antioxidants are well known for possessing anti-inflammatory properties, which can reduce the risk of chronic disease and obesity. However, very little research has been done to examine antioxidant intake among adolescent minority populations such as Native American adolescents. Our study examined significance adolescents at an urban residential high school in Southern California. population consisted 183 male female adolescents, 14-18 years age, representing 43 tribes from across United...
Antioxidants are well‐known for possessing anti‐inflammatory properties which can reduce the risk of chronic disease and obesity. However, very little research has been done to examine antioxidant intake among adolescent minority populations such as Native American adolescents. Our study examined significance adolescents at an urban residential high school in Southern California. population consisted 183 male female adolescents, 14‐18 years age, representing 43 tribes from across United...
Improving nutrition and declining the rate of obesity have been demonstrated through many reports. Identifying among adolescent minority populations long recognized, but little research has done on Native Americans adolescents. Using anthropometric measurements dietary assessments, findings within each study shown to obtain baseline measures determine prevalence Sherman American population. Data assessment appears be use for predicting creating effective future interventions. Compiling data...
Abstract Objectives To study the effect of selenocystine (Selenocystine, SeC) on radiosensitivity human cervical cancer Hela cells, and to provide a new target for cancer. Methods SeC were added then irradiate with 200 cGy/min X‐rays. The radiosensitization cells confirmed experiments cell growth inhibition, clone formation, flow cytometry Western blotting detect apoptosis. Results at different doses 0, 5, 10, 20 μmol/L incubating 24 hours, inhibition rates were: 0%, 22.68%, 41.71%, 74.19%,...
A volunteer sample of 100 first-year college students were recruited to examine their body fat percentage levels and investigate the association between physical activity.Body scores regressed stepwise on students' vigorous activity, moderate walking, gender.The results regression indicated that model explained 35.0% variance, two factors such as PA gender significant predictors percentage, F(1.78)=56.00,p<0.001.The rest variables entered these not factors.
Obesity is becoming increasingly prevalent among US adolescents due to various factors such as food preference, availability, and social condition: however, rates of obesity in Native American are comparatively much higher than their counterparts differences 7.2% have been reported between white adolescents. Given extensive study highlighting the highly harmful effects overall health that consuming trans fats has linked to, this investigated dietary intake levels by explored implications...
latter had higher obesity rates than the former [3].According to a High School Youth Behavior Risk study conducted by Center for Disease Control and Prevention (CDC), of among white students were 13.1% 21.3% Native Americans[4], difference that is concerning worth investigating.In our previous utilizing same survey data used in this study, it was discovered at American school surveyed doubled.Furthermore, findings from Maternal Child Health Journal stated children are most obese...