A5102830819- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Physiological and biochemical adaptations
- Crustacean biology and ecology
- Animal Nutrition and Physiology
- Environmental Toxicology and Ecotoxicology
- Neurobiology and Insect Physiology Research
- Invertebrate Immune Response Mechanisms
- Marine Bivalve and Aquaculture Studies
- Gut microbiota and health
- Aquatic life and conservation
- Reproductive biology and impacts on aquatic species
- Parasite Biology and Host Interactions
- Trace Elements in Health
- Protein Hydrolysis and Bioactive Peptides
- Autophagy in Disease and Therapy
- Chromium effects and bioremediation
- Rabbits: Nutrition, Reproduction, Health
- Iron Metabolism and Disorders
- Effects of Environmental Stressors on Livestock
- Barrier Structure and Function Studies
- Antioxidant Activity and Oxidative Stress
- Peroxisome Proliferator-Activated Receptors
- TGF-β signaling in diseases
- Lipid metabolism and biosynthesis
Ningbo University
2019-2025
Massachusetts General Hospital
2018-2023
Harvard University
2018-2023
Bridge University
2022
Cambridge University Press
2022
New York University Press
2022
Zhejiang University
2013-2021
Ministry of Agriculture and Rural Affairs
2018-2021
University Hospital Heidelberg
2015
Heidelberg University
2015
The current study investigated the efficacy of a probiotic mixture on ameliorating heat stress-induced impairment intestinal microflora, morphology, and barrier integrity in broilers. contained Bacillus licheniformis, subtilis, Lactobacillus plantarum. Three hundred sixty 21-d-old Ross 308 male broilers were allocated 4 experimental treatments, each which was replicated 6 times with 15 per replicate. A 2 × factorial design used study, main factors composed diet (basal or addition 1.5 g/kg...
In the present study, we investigated influence of diquat-induced oxidative stress on intestinal barrier, mitochondrial function, and level mitophagy in piglets. Twelve male Duroc × Landrace Yorkshire 35-d-old pigs (weaned at 21 d age), with an average body 9.6 kg, were allotted to two treatments six piglets each including challenged group control group. The injected 100 mg/kg bodyweight diquat 0.9% (w/v) NaCl solution. results showed that injection decreased ADFI ADG. Diquat (P < 0.05)...
In the present study, we investigated influence of weaning on antioxidant status, intestinal integrity, mitochondrial function, and mitophagy level in piglets (weaned at 21 d) during 1 wk after weaning. The redox status was measured by enzymes activities, related genes expression, malondialdehyde (MDA) content jejunum. barrier function assessed Ussing chamber expression tight junction proteins intestine mitochondria DNA (mtDNA) activities oxidative phosphorylation complexes. levels light...
Here we investigated the influence of LPS-induced gut injury on antioxidant homeostasis, mitochondrial (mt) function and level mitophagy in piglets. The results showed that intestinal decreased transepithelial electrical resistance, increased paracellular permeability F1TC dextran 4 kDa, expression claudin-1, occludin zonula occludens-1 jejunum compared with control group. LPS activities superoxide dismutase (SOD) glutathione peroxidase (GSH-Px), content malondialdehyde jejunum. Meanwhile,...
Abstract The present study aimed to investigate whether dietary choline can regulate lipid metabolism and suppress NFκB activation and, consequently, attenuate inflammation induced by a high-fat diet in black sea bream ( Acanthopagrus schlegelii ). An 8-week feeding trial was conducted on fish with an initial weight of 8·16 ± 0·01 g. Five diets were formulated: control, low-fat (11 %); HFD, (17 HFD supplemented graded levels (3, 6 or 12 g/kg) termed + C1, C2 C3, respectively. Dietary...
This experiment was conducted to investigate the effect of exposure high altitude and low oxygen on intestinal microbial communities using mice as an animal model. Fecal microbiota from housed in a control environment representing 2,200 meters (NC group) above sea level with 16% Oxygen that were placed hypobaric chamber 5000 (HC 11% for 30 days, analyzed by HiSeq Illumina sequencing platform. The results showed significant difference beta diversity observed between two groups, while no alpha...
A series of modified montmorillonites (Mt) including zinc-loaded Mt (Zn-Mt), copper-loaded (Cu-Mt), copper/zinc-loaded with different Cu/Zn ratio (Cu/Zn-Mt-1, Cu/Zn-Mt-2, Cu/Zn-Mt-3) were prepared by an ion-exchange reaction, and characterized using X-ray diffraction (XRD), fourier transformed infrared spectroscopy (FTIR) transmission electron microscopy (TEM). The specific surface areas, antimicrobial activity cytotoxicity the investigated. In Mt, hydrated Cu ions Zn exchanged in interlayer...
Hyaluronan is a glycosaminoglycan polymer that has been shown to play an important role in homeostasis of the gastrointestinal tract. However, its mechanistic significance epithelial barrier elements remain unexplored. Here, our results revealed hyaluronan treatment resulted significant changes gut microbiota mice. To demonstrate functional consequences hyaluronan-treatment and hyaluronan-induced alterations, Citrobacter rodentium- DSS-induced colitis models transplantation approaches were...
An eight-week feeding trial was conducted to investigate the effects of dietary lipid sources on growth performance, fatty acids composition in tissue and expression genes related metabolism juvenile largemouth bass (Micropterus salmoides). Four experimental diets were formulated contain 6% coconut oil (CO), rapeseed (RO), linseed (LO) fish (FO), respectively. Each diet fed triplicate groups for 8 weeks. The results indicated that final body weight (FBW), percent gain (PWG), specific rate...
The regulation of lipogenesis and lipolysis mechanisms related to consumption lipid has not been studied in swimming crab. aims the present study were evaluate effects dietary levels on growth, enzymes activities expression genes metabolism hepatopancreas juvenile Three isonitrogenous diets formulated contain crude at 5·8, 9·9 15·1 %. Crabs fed diet containing % had significantly lower growth performance feed utilisation than those 5·8 diets. malondialdehyde concentrations haemolymph other...
The present study aimed to elucidate the mechanism of dietary betaine, as a lipid-lowering substance, on regulation lipid metabolism and inflammation in juvenile black seabream ( Acanthopagrus schlegelii ) fed high fat diet. An 8-week feeding trial was conducted with an initial weight 8.39 ± 0.01g four isonitrogenous diets including Control, medium-fat diet (11%); HFD, high-fat (17%); HFD supplemented two levels (10 20 g/kg) HFD+B1 HFD+B2, respectively. SGR FE fish HFD+B2 were significantly...