- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Coccidia and coccidiosis research
- Vector-borne infectious diseases
- Helminth infection and control
- Viral Infections and Vectors
- Toxoplasma gondii Research Studies
- Dermatological diseases and infestations
- Mycobacterium research and diagnosis
- Vector-Borne Animal Diseases
- Parasitic infections in humans and animals
- Parasites and Host Interactions
- Insect and Pesticide Research
- Viral gastroenteritis research and epidemiology
- Veterinary medicine and infectious diseases
- Mosquito-borne diseases and control
- Microbial infections and disease research
- Study of Mite Species
- Clostridium difficile and Clostridium perfringens research
- Parasite Biology and Host Interactions
- Orthopedic Infections and Treatments
- Yersinia bacterium, plague, ectoparasites research
- Respiratory viral infections research
- Aquaculture disease management and microbiota
- Plant and Fungal Interactions Research
Henan Agricultural University
2016-2025
Henan Provincial Center for Disease Control and Prevention
2012-2025
Ministry of Agriculture and Rural Affairs
2023-2025
Karamay Central Hospital of Xinjiang
2024
Urumqi Vocational University
2024
Shenzhen Children's Hospital
2008-2022
Creative Commons
2021
Massachusetts General Hospital
2021
Harvard University
2021
Weatherford College
2021
ABSTRACT Enterocytozoon bieneusi is an important zoonotic pathogen. To assess the human-infective potential of E. in nonhuman primates (NHPs), we examined prevalence and genotype distribution 23 NHP species by PCR sequence analysis ribosomal internal transcribed spacer (ITS). A total 1,386 fecal specimens from NHPs five provinces China were examined, was detected 158 (11.4%) species, including cynomolgus monkey (67.7%), rhesus macaque (8.8%), Japanese (33.3%), white-headed langur (13.6%),...
To estimate the prevalence and public health significance of cryptosporidiosis in preweaned calves China, 801 fecal samples from eight farms seven areas Henan Province were examined for Cryptosporidium oocysts. The overall infection rate was 21.5%, with farm Xinxiang having highest (40%). No significant difference rates observed between seasons. spp. characterized by PCR-restriction fragment length polymorphism (RFLP) analysis small subunit (SSU) rRNA gene DNA sequencing 60-kDa glycoprotein...
To appreciate the genetic diversity and zoonotic implications of Enterocytozoon bieneusi in nonhuman primates (NHPs) zoos, we genotyped E. captive NHPs seven zoos located at six major cities China, using ribosomal internal transcribed spacer (ITS)-based PCR sequence analyses. A total 496 fecal specimens from 36 NHP species under nine families were analyzed was detected 148 (29.8%) 25 families, including Cercopithecidae (28.7%), Cebidae (38.0%), Aotidae (75.0%), Lemuridae (26.0%), Hylobatidae...
To explore the genetic diversity, host specificity, and zoonotic potential of Enterocytozoon bieneusi, feces from 348 stray pet dogs 96 cats different locations in China were examined by internal transcribed spacer (ITS)-based PCR. E. bieneusi was detected 15.5% dogs, including 20.5% 11.7% 11.5% cats. Higher infection rates recorded >2-year 1- to 2-year age groups cats, respectively. Altogether, 24 genotypes, 11 known 13 new, 65 infected animals. In 54 positive 18 9 (PtEbIX, O, D, CM1, EbpA,...
Background Cryptosporidium spp. are common parasites of humans and animals. Farm animals, especially pre-weaned calves, considered to be one main animal reservoir hosts in the transmission human cryptosporidiosis. The aim this study was determine distribution genotypes calves using molecular tools assess zoonotic elucidate public health significance northeastern China. Methodology/Principal Findings A total 151 fecal specimens from were collected Heilongjiang Province screened for by PCR....
Cryptosporidium spp. and Giardia duodenalis are important gastrointestinal protists in humans animals worldwide. In China, bovine cryptosporidiosis giardiasis of increasing concern because cattle reservoirs these parasites, which have become potential threats to public health large numbers recent years. A total 1366 fecal samples from the Ningxia Autonomous Region were examined. The overall infection rates for G. 1.61% 2.12%, respectively. was only detected preweaned calves adults older than...
To understand the prevalence of Cryptosporidium infection in rodents China and to assess potential role as a source for human cryptosporidiosis, 723 specimens from 18 rodent species were collected four provinces examined between August 2007 December 2008 by microscopy after using Sheather's sugar flotation modified acid-fast staining. oocysts detected 83 specimens, with an overall 11.5%. Phodopus sungorus, campbelli, Rattus tanezumi new reported hosts Cryptosporidium. The genotypes subtypes...
Abstract Cryptosporidium spp., Giardia duodenalis , and Enterocytozoon bieneusi are common gastrointestinal protists in humans animals. Two hundred three fecal specimens from 80 wildlife species were collected Zhengzhou Zoo their genomic DNA extracted. Three intestinal pathogens characterized with a sequence analysis of different loci. felis C. baileyi avian genotype III identified (1.5%), the manul, red‐crowned crane, cockatiel, respectively. was also found five (2.5%) firstly: assemblage B...
Over recent years, several studies have conducted genotyping of Enterocytozoon bieneusi in various hosts worldwide using sequence analysis the ribosomal internal transcribed spacer (ITS), however, relatively little is known about E. sheep and goats China. Therefore this research was to understand prevalence genotype distribution farmed A total 1025 fecal specimens from animals geographic areas were collected. Overall, PCR ITS detected 34.4 % (353/1025) isolates; which 28.8 (176/611) 42.8...
Giardia duodenalis is a common and widespread intestinal protozoan parasite of both humans animals. Previous epidemiological molecular studies have identified infections in different animals humans, but only limited information available about the occurrence genotypes cattle China. In this study, we determined giardiasis genetically characterized G. dairy Henan Province, central The overall prevalence was 7.2% (128/1777) on microscopic analysis, with highest infection rate (22.7%) calves...
In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes detected at each the 12 microsatellite, minisatellite single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation significant geographical segregation both observed A clonal population structure was seen C. China Sweden. Three ancestral lineages same RPGR shared these examined....
Enterocytozoon bieneusi is the most frequently diagnosed microsporidian species in humans and a wide range of animals. This study was conducted to assess prevalence molecular characteristics E. dairy cattle Henan Province central China Ningxia Hui Autonomous Region northwest China.Of 879 fresh fecal specimens, 24.3 % (214/879) tested positive for by nested polymerase chain reaction (PCR) based on internal transcriber spacer (ITS) gene. The highest infection rate, 46.8 (51/109, P < 0.0001),...
Hyaluronan is a glycosaminoglycan polymer that has been shown to play an important role in homeostasis of the gastrointestinal tract. However, its mechanistic significance epithelial barrier elements remain unexplored. Here, our results revealed hyaluronan treatment resulted significant changes gut microbiota mice. To demonstrate functional consequences hyaluronan-treatment and hyaluronan-induced alterations, Citrobacter rodentium- DSS-induced colitis models transplantation approaches were...
Abstract A range of public health measures have been implemented to suppress local transmission coronavirus disease 2019 (COVID-19) in Shenzhen. We examined the effect these on prevalence respiratory pathogens children. Clinical and pathogen data were collected for routine care from hospitalized children with acute infections Shenzhen Children’s Hospital July 2018 January 2022. Nasopharyngeal swabs detected using standardized clinical diagnostics as part care. Data analyzed describe effects...
Background Giardia duodenalis is a widespread intestinal protozoan of both humans and mammals. To date, few epidemiological studies have assessed the potential importance zoonotic transmission; human giardiasis burden attributable to G. animal origin unclear. No information about occurrence genotyping data sheep goat available in China. The aim present study was determine prevalence distribution goats Heilongjiang Province, China, characterize isolates assess possibility transmission....
Cryptosporidium spp. are zoonotic parasites responsible for diarrhoeal diseases in animals and humans worldwide. Cattle the most common mammalian species which is detected, with pre-weaned calves considered to be reservoirs C. parvum. In October 2013, severe diarrhoea was observed 396 at a farm Ningxia Autonomous Region of Northwestern China. 356 infected died despite antibiotic therapy. 252 faecal samples were collected from investigated farm. The identity determined by polymerase chain...