A5022577082- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Coccidia and coccidiosis research
- Toxoplasma gondii Research Studies
- Helminth infection and control
- Vector-borne infectious diseases
- Viral gastroenteritis research and epidemiology
- Veterinary medicine and infectious diseases
- Parasitic infections in humans and animals
- Viral Infections and Vectors
- Mycobacterium research and diagnosis
- Microbial infections and disease research
- Clostridium difficile and Clostridium perfringens research
- Parasites and Host Interactions
- Dermatological diseases and infestations
- Herpesvirus Infections and Treatments
- Vector-Borne Animal Diseases
- Insect and Pesticide Research
- Rabies epidemiology and control
- Parasite Biology and Host Interactions
- Animal Nutrition and Physiology
- Congenital Anomalies and Fetal Surgery
- Yersinia bacterium, plague, ectoparasites research
- Study of Mite Species
- Mosquito-borne diseases and control
Henan Agricultural University
2016-2025
Henan Provincial Center for Disease Control and Prevention
2015-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Yunnan Normal University
2024
Yunnan Provincial Department of Education
2024
Bridge University
2024
Xian Yang Central Hospital
2021
Biomedical Research Center of the Slovak Academy of Sciences
2020
Zhengzhou University
2020
Henan Normal University
2020
Molecular diagnostic tools have been used increasingly in the characterization of transmission cryptosporidiosis and microsporidiosis developing countries. However, few studies examined distribution Cryptosporidium species Enterocytozoon bieneusi genotypes AIDS patients receiving antiretroviral therapy. In present study, 683 HIV-positive National Free Antiretroviral Therapy Program China matched HIV-negative controls were enrolled. subtypes detected differentiated by PCR DNA sequencing. The...
Abstract Cryptosporidium ubiquitum is an emerging zoonotic pathogen. In the past, it was not possible to identify association between cases of human and animal infection. We conducted a genomic survey species, developed subtyping tool targeting 60-kDa glycoprotein (gp60) gene, identified 6 subtype families (XIIa–XIIf) C. ubiquitum. Host adaptation apparent at gp60 locus; XIIa found in ruminants worldwide, XIIb–XIId were rodents United States, XIIe XIIf Slovak Republic. Humans States infected...
ABSTRACT Enterocytozoon bieneusi is an important zoonotic pathogen. To assess the human-infective potential of E. in nonhuman primates (NHPs), we examined prevalence and genotype distribution 23 NHP species by PCR sequence analysis ribosomal internal transcribed spacer (ITS). A total 1,386 fecal specimens from NHPs five provinces China were examined, was detected 158 (11.4%) species, including cynomolgus monkey (67.7%), rhesus macaque (8.8%), Japanese (33.3%), white-headed langur (13.6%),...
To estimate the prevalence and public health significance of cryptosporidiosis in preweaned calves China, 801 fecal samples from eight farms seven areas Henan Province were examined for Cryptosporidium oocysts. The overall infection rate was 21.5%, with farm Xinxiang having highest (40%). No significant difference rates observed between seasons. spp. characterized by PCR-restriction fragment length polymorphism (RFLP) analysis small subunit (SSU) rRNA gene DNA sequencing 60-kDa glycoprotein...
To appreciate the genetic diversity and zoonotic implications of Enterocytozoon bieneusi in nonhuman primates (NHPs) zoos, we genotyped E. captive NHPs seven zoos located at six major cities China, using ribosomal internal transcribed spacer (ITS)-based PCR sequence analyses. A total 496 fecal specimens from 36 NHP species under nine families were analyzed was detected 148 (29.8%) 25 families, including Cercopithecidae (28.7%), Cebidae (38.0%), Aotidae (75.0%), Lemuridae (26.0%), Hylobatidae...
To explore the genetic diversity, host specificity, and zoonotic potential of Enterocytozoon bieneusi, feces from 348 stray pet dogs 96 cats different locations in China were examined by internal transcribed spacer (ITS)-based PCR. E. bieneusi was detected 15.5% dogs, including 20.5% 11.7% 11.5% cats. Higher infection rates recorded >2-year 1- to 2-year age groups cats, respectively. Altogether, 24 genotypes, 11 known 13 new, 65 infected animals. In 54 positive 18 9 (PtEbIX, O, D, CM1, EbpA,...
Background Cryptosporidium spp. are common parasites of humans and animals. Farm animals, especially pre-weaned calves, considered to be one main animal reservoir hosts in the transmission human cryptosporidiosis. The aim this study was determine distribution genotypes calves using molecular tools assess zoonotic elucidate public health significance northeastern China. Methodology/Principal Findings A total 151 fecal specimens from were collected Heilongjiang Province screened for by PCR....
Cryptosporidium spp. and Giardia duodenalis are important gastrointestinal protists in humans animals worldwide. In China, bovine cryptosporidiosis giardiasis of increasing concern because cattle reservoirs these parasites, which have become potential threats to public health large numbers recent years. A total 1366 fecal samples from the Ningxia Autonomous Region were examined. The overall infection rates for G. 1.61% 2.12%, respectively. was only detected preweaned calves adults older than...
To understand the prevalence of Cryptosporidium infection in rodents China and to assess potential role as a source for human cryptosporidiosis, 723 specimens from 18 rodent species were collected four provinces examined between August 2007 December 2008 by microscopy after using Sheather's sugar flotation modified acid-fast staining. oocysts detected 83 specimens, with an overall 11.5%. Phodopus sungorus, campbelli, Rattus tanezumi new reported hosts Cryptosporidium. The genotypes subtypes...
Abstract Cryptosporidium spp., Giardia duodenalis , and Enterocytozoon bieneusi are common gastrointestinal protists in humans animals. Two hundred three fecal specimens from 80 wildlife species were collected Zhengzhou Zoo their genomic DNA extracted. Three intestinal pathogens characterized with a sequence analysis of different loci. felis C. baileyi avian genotype III identified (1.5%), the manul, red‐crowned crane, cockatiel, respectively. was also found five (2.5%) firstly: assemblage B...
The switch from photosynthetic or predatory to parasitic life strategies by apicomplexans is accompanied with a reductive evolution of genomes and losses metabolic capabilities. Cryptosporidium an extreme example among apicomplexans, both the mitosome genome many pathways. Previous observations on were largely based comparative studies various groups apicomplexans. In this study, we sequenced two divergent species conducted genomic analysis infer pathways differential invasion-related...
Abstract Four Cryptosporidium spp. and 6 C. hominis subtypes were isolated from 102 of 6,284 patients in 3 pediatric hospitals People’s Republic China. A cryptosporidiosis outbreak was identified retrospectively. The lasted >1 year affected 51.4% 1 hospital ward, where 2 with different virulence found.
Over recent years, several studies have conducted genotyping of Enterocytozoon bieneusi in various hosts worldwide using sequence analysis the ribosomal internal transcribed spacer (ITS), however, relatively little is known about E. sheep and goats China. Therefore this research was to understand prevalence genotype distribution farmed A total 1025 fecal specimens from animals geographic areas were collected. Overall, PCR ITS detected 34.4 % (353/1025) isolates; which 28.8 (176/611) 42.8...
Giardia duodenalis is a common and widespread intestinal protozoan parasite of both humans animals. Previous epidemiological molecular studies have identified infections in different animals humans, but only limited information available about the occurrence genotypes cattle China. In this study, we determined giardiasis genetically characterized G. dairy Henan Province, central The overall prevalence was 7.2% (128/1777) on microscopic analysis, with highest infection rate (22.7%) calves...
In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes detected at each the 12 microsatellite, minisatellite single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation significant geographical segregation both observed A clonal population structure was seen C. China Sweden. Three ancestral lineages same RPGR shared these examined....