A5064661665- Oral microbiology and periodontitis research
- Brain Metastases and Treatment
- Breast Cancer Treatment Studies
- Glioma Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Periodontal Regeneration and Treatments
- Lung Cancer Research Studies
- Oral and gingival health research
- Colorectal and Anal Carcinomas
- Endometrial and Cervical Cancer Treatments
- Cancer Genomics and Diagnostics
- BRCA gene mutations in cancer
- Intraperitoneal and Appendiceal Malignancies
- Sarcoma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Ovarian cancer diagnosis and treatment
- CRISPR and Genetic Engineering
- Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- HIV/AIDS oral health manifestations
- Veterinary Oncology Research
- Radiopharmaceutical Chemistry and Applications
- Acute Lymphoblastic Leukemia research
- Endodontics and Root Canal Treatments
- Lymphoma Diagnosis and Treatment
Malmö University
2024
University of Illinois Urbana-Champaign
2024
Lancaster University
2011
The Netherlands Cancer Institute
1997-2008
Weatherford College
2007
University of Amsterdam
1987-2002
Amsterdam UMC Location University of Amsterdam
1987-2002
Royal Belgian Society for Surgery
2000
Radiotherapie Groep
1997
Oncode Institute
1982-1996
A retrospective clinico-pathological study has been carried out in a series of 405 patients with squamous cell carcinoma the head and neck who underwent total 484 radical dissections. The recurrence rate 327 had histological positive nodes was 21.1%. Recurrence after standard dissection almost invariably proved fatal. statistical analysis to evaluate clinical pathological factors which are importance regards neck. Histological such as extra-nodal spread number have shown be much more...
Naturally occurring skeletal osteosarcomas in a series of 144 untreated dogs were found especially to involve the ends long bones forelimbs and affected predominantly older male giant large breeds. Most tumors partially necrotic had extended into soft tissues. Of 12 host tumor characteristics tested first part study, diameter volume significantly associated with presence pulmonary metastases at autopsy. The second study revealed that extension tissues localization hind legs poor prognosis,...
<h3>Objectives:</h3> To evaluate the overexpression of cyclin<i>D1</i>and<i>p53</i>as a prognostic marker squamous cell carcinoma head and neck to investigate whether deregulation these genes is associated with an unfavorable course disease. <h3>Design:</h3> Retrospective study. <h3>Materials Methods:</h3> Formalin-fixed, paraffinembedded tumor materials that were obtained from well-characterized series 115 patients resectable cancer at The Netherlands Cancer Institute, Amsterdam, analyzed...
BACKGROUND: Various histological classifications developed for nodal lymphomas failed to be of value in extranodal lymphomas. More recently, gastric lymphoma is considered represent a distinctive group derived from mucosa associated lymphoid tissue (MALT). AIM: To study the prognostic malignancy grading based on concept that most are MALT origin, endoscopic as well clinical characteristics 114 patients with primary non-Hodgkin9s were evaluated. RESULTS: In univariate analysis, low grade (n =...
Summary. Thirteen preoperative and operative factors were investigated regarding their association with the incidence of postoperative pain after first session root canal treatment. The final analysis comprised 443 teeth patients. These remaining original sample 1204 was reduced by exclusion all associated irrelevant which could possibly affect analysis. results showed that visit occurred in 27 per cent cases (5 severe 22 moderate pain). Positive correlation between several factors: presence...
From a follow-up study of dogs surgically treated for mammary cancer, ten characteristics were analyzed statistically with special reference to their association prognosis (expressed as survival 2 years). The interrelations among five the also tested. histologic type (descending range in malignancy: sarcomas greater than simple carcinomas complex carcinomas), mode growth (highly infiltrating moderately expansive), clinical stage (large tumors and/or involving skin or underlying tissue small,...
Abstract The effect of improved metabolic control on the clinical periodontal condition and subgingival microflora diseased healthy pockets in 6 ambulatory insulin‐dependent diabetes mellitus (IDDM) patients was prospectively studied. Duplicate measurements with a time‐interval 3 days were made every 4 moths for assessment status, microflora. During study, maintained personal oral hygiene measures as they usually did before study. Neither supplementary dental prophylaxis nor applied during...
Aims: Goblet cell carcinoid is a poorly understood tumour of the appendix. The aim this study was to determine whether it should be regarded as separate entity or variant classical carcinoid. Methods and results: immunohistochemical expression pattern 21 markers mutation status KRas codon 12 were determined in 16 goblet carcinoids compared with 14 carcinoids, 19 colonic adenocarcinomas 10 appendiceal mucinous cystadeno (carcino)mas. results subjected stepwise linear discriminant analysis....
The purpose of the present investigation was to study effect standardization probing spot and direction probe insertion into pocket in conjunction with a force 0.75 N on reproducibility depth measurements. Nine patients were selected basis about 50 % loss alveolar bone support. After initial treatment 137 interproximal pockets measured twice by three different examiners, successively means pressure constant Merritt‐B probe. During next two weeks examiners trained video program use...
We investigated the prognostic significance of circulating breast cancer cells in peripheral blood detected by quantitative RT–PCR marker genes patients with advanced cancer. Blood samples from 94 metastatic disease (M1) were examined for tumour studying mRNA expression CK19, p1B, PS2 and EGP2 real-time PCR. Using a score function, developed predicting quadratic discriminant analysis (QDA), four levels combined into single value. Tumour present 24 out (31%) patients. In 77% (72 94) distant...
Background: Numerous low-penetrance genes control susceptibility to cancer in experimental animals, but the overall genetic information on this group of (i.e., number loci and their mutual interactions) is missing. We performed a systematic search, scanning roughly half mouse genome for lung (Sluc) affecting tumor size or by using recombinant congenic (RC) strains. In each RC strain (OcB), approximately 12.5% derived from cancer-resistant B10.O20, whereas rest cancer-susceptible O20....
The predisposition to colon cancer is multigenetically controlled in animals and probably also humans. We have analyzed the multigenic control of susceptibility 1,2-dimethylhydrazine-induced tumors mice by using a set 20 homozygous CcS/Dem recombinant congenic strains, each which contains different random subset approximately 12.5% genes from susceptible strain STS/A 87.5% relatively resistant BALB/cHeA. Some strains received alleles at one or more multiple tumor loci are susceptible,...
We examined the prevalence of mental health problems in refugees living camps that emerged Tanzania during Rwanda crisis started 1994.Using 28-item version General Health Questionnaire (GHQ-28), we two samples: a random sample (n = 854) and clients psychosocial support programme these 23). Sensitivity, specificity positive- negative predictive values were estimated for several cut-off scores GHQ-28.The serious was at 50% (SE 12%). When using GHQ-28 as screener, score 14 is recommended.Given...