A5101717544- Genomics, phytochemicals, and oxidative stress
- Neuroinflammation and Neurodegeneration Mechanisms
- Biochemical and biochemical processes
- Bacterial Identification and Susceptibility Testing
- Pluripotent Stem Cells Research
- Antibiotic Use and Resistance
- Nuclear Receptors and Signaling
- Sulfur Compounds in Biology
- Tryptophan and brain disorders
- Clinical Laboratory Practices and Quality Control
- Nerve injury and regeneration
- Parkinson's Disease Mechanisms and Treatments
- Aldose Reductase and Taurine
- Free Radicals and Antioxidants
- Heme Oxygenase-1 and Carbon Monoxide
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Bioactive natural compounds
- Mesenchymal stem cell research
- Signaling Pathways in Disease
- Eicosanoids and Hypertension Pharmacology
University of Ulsan
2013-2021
Ulsan College
2013-2021
Korea Center for Disease Control and Prevention
2015
The anti-oxidant enzyme heme oxygenase-1 (HO-1) is known to exert anti-inflammatory effects. From a library of pyrazolo[3,4-
BACKGROUND AND PURPOSE In Parkinson's disease, the dopaminergic neurones in substantia nigra undergo degeneration. While exact mechanism for degeneration is not completely understood, neuronal apoptosis and neuroinflammation are thought to be key contributors. We have recently established that MMP‐3 plays crucial roles cell death microglial activation. EXPERIMENTAL APPROACH tested effects of 7‐hydroxy‐6‐methoxy‐2‐propionyl‐1,2,3,4‐tetrahydroisoquinoline (PTIQ) on expression inflammatory...
The degenerative process of the nigral dopamine(DA)rgic neurons in Parkinson's disease (PD) involves both oxidative stress and neuroinflammation. In present study, we aimed at developing a novel antioxidant anti-inflammatory agent for PD therapy. Toward this end, screened focused library isothiocyanate derivatives that have generated an property. We obtained compound ITC-57 found effectively induced gene expression enzymes NAD(P)H quinone oxidoreductase-1, catalytic modulatory subunits...
Transplantation of neural stem cells has been reported as a possible approach for replacing impaired dopaminergic neurons. In this study, we tested the efficacy early-stage human dental papilla-derived and brain-derived in rat models 6-hydroxydopamine-induced Parkinson's disease. Rats received unilateral injection 6-hydroxydopamine into right medial forebrain bundle, followed 3 weeks later by injections PBS, cells, or ipsilateral striatum. All rats cell group died from tumor formation at...
Quality control (QC) processes are being performed in the majority of clinical microbiology laboratories to ensure performance microbial identification and antimicrobial susceptibility testing by using ATCC strains. To obtain these strains, some inconveniences encountered concerning purchase cost strains shipping time required. This study was focused on constructing a database reference for QC domestic bacterial concentrating primarily testing. Three (Escherichia coli, Pseudomonas...