Patients with a history of mild TBI (post-mTBI-patients) have an unexplained increase in long-term mortality which might be related to central autonomic dysregulation (CAD). We investigated whether standardized baroreflex-loading, induced by Valsalva maneuver (VM), unveils CAD otherwise healthy post-mTBI-patients.In 29 persons (31.3 ± 12.2 years; 9 women) and 25 post-mTBI-patients (35.0 13.2 years, 7 women, 4-98 months post-injury), we monitored respiration (RESP), RR-intervals (RRI)...

Abstract Background High levels of childhood trauma (CT) have been observed in adults with mental health problems. Herein, we investigated whether self-esteem (SE) and emotion regulation strategies (cognitive reappraisal (CR) expressive suppression (ES)) affect the association between CT adulthood, including depression anxiety symptoms. Methods We performed a cross-sectional study 6057 individuals (39.99% women, median age = 34 y), recruited across China via internet, who completed Patient...

Abstract Background Nitrous oxide has become a popular inhalant as abused substance by young Chinese people in recent years. It been mainly associated with medical conditions including megaloblastic anemia and myeloneuropathy. Case presentation We report case of 25-year-old high school graduate who had abusing nitrous for twenty months. She history peripheral neuropathy subacute combined degeneration between. The woman presented headache, motor aphasia right arm paralysis eight hours after...

Background: Fingolimod slows heart rate (HR) due to vagomimetic effects and might cause additional cardiovascular autonomic changes. While the time course of HR changes is well described, extent upon fingolimod initiation has not yet been evaluated. This study, therefore, intended assess during first 6 h after initiation. Methods: In 21 patients with relapsing-remitting multiple sclerosis (RRMS), we recorded respiration (RESP), electrocardiographic RR interval (RRI), systolic diastolic blood...

How to design a robotic hand reflecting human motion information as much possible is constantly exploring problem. In this paper, we propose an approach mechanical of compliant underactuated finger for prosthetic based on the decomposition movements. Hand movements are decomposed into primary and secondary in PCA coordinate system. The achieved free via actuators, implemented with compliance matching statistics characteristic data. Although analysis single always throughout same method can...

Because hand is often used for grasping, developing a design of prosthetic hands, particularly light and compact underactuated anthropomorphic transradial prostheses reproducing human complex grasping crucial upper-limb amputees. Obviously, the less number actuators is, worse motion capability hands will be. This paper aims to transmission mechanism with few motors actuating fingers which could serve relatively accurate grasp movement has potential be embedded in palm including motors. We...

Objective: Uric acid as an antioxidant plays important role in neurodegenerative disease. Our objective is to investigate the relationship between plasma uric and cognitive impairment patients with amyotrophic lateral sclerosis (ALS). Methods: In this cross-sectional study, 124 ALS were screened by Edinburgh Cognitive Behavioral Screen (ECAS) classified according revised Strong's criteria. Additionally, based on total ECAS cut-off score categorized into those (ALS-cie) without (ALS-ncie),...

This case report describes a diagnosis of dipeptidyl-peptidaselike protein-6 antibody-associated encephalitis in woman aged 51 years who presented with progressive gait instability, memory impairment, and weight loss.

Pneumonia is a bacteria, virus, or fungus that infects one both lungs, causing the alveoli to fill with fluid pus. More than 15% of deaths include children under age five are caused by pneumonia globally. This disease usually diagnosed chest X-ray. The rich labeled data sets verify effectiveness deep learning technology. In this study, paper describes method based on automatically identify and locate location X- ray images. We have constructed new detection model, which model obtained...

Abstract Background ALS patients have changed peripheral immunity. It is unknown whether immunity related to cognitive dysfunction in patients. Objective To explore the relationship between blood lymphocyte subsets and status Methods Among 81 patients, we compared demographic, clinical, levels of total T lymphocyte, CD4+ CD8+ B NK cell those with impairment (ALS-ci) without (ALS-nci). The was evaluated via Chinese version Edinburgh behavioral screen (ECAS). Significant predictors univariate...

Patients with a history of mild traumatic brain injury (post-mTBI patients) may have enduring cardiovascular-autonomic dysregulation and emotional problems. Olfactory stimulation (OS) triggers responses that might be compromised in post-mTBI patients. We therefore evaluated these to OS In 17 patients (interval since mTBI: 32.4 ± 6.8 months) age- sex-matched controls, we recorded respiration, electrocardiographic RR intervals, systolic diastolic blood pressures (BPsys, BPdia) before during...

Abstract Data pertaining to risk factor analysis in coronavirus disease 2019 (COVID‐19) is confounded by the lack of data from an ethnically diverse population. In addition, there a for young adults. This study was conducted assess factors predicting COVID‐19 severity and mortality hospitalized A retrospective observational at two centers China India on patients aged 20–50 years. Regression predict adverse outcomes performed using parameters including age, sex, country origin,...

<title>Abstract</title> Objectives To investigate the relationship between visual pathway and disease duration cognitive function in patients with amyotrophic lateral sclerosis (ALS). Methods 31 ALS 20 healthy controls were enrolled. Patients categorized into ALS-early ALS-late groups according to duration. Edinburgh Cognitive Behavioral Screen (ECAS) was performed for all patients. Retinal nerve fiber layer (RNFL) thickness via optical coherence tomography (OCT), fractional anisotropy (FA)...

Background The aldehyde dehydrogenase 2 ( ALDH2 ) rs671 (A) allele has been implicated in neurodegeneration, potentially through oxidative and inflammatory pathways. study aims to investigate the effects of high sensitivity C-reactive protein (hs-CRP) on clinical phenotypes amyotrophic lateral sclerosis (ALS) male female patients. Methods Clinical data genotype 143 ALS patients, including 85 males 58 females, were collected from January 2018 December 2022. All patients underwent assessment...

The interpretation of chest x-rays is critical for the discovery thoracic diseases, including pneumonia and lung cancer, which affect millions people worldwide each year. This time-consuming task usually requires radiologists to read images, leading diagnostic errors due fatigue lack expertise in areas where there are no world. Recently, deep learning methods have been able perform well field medical imaging, thanks emergence large network architectures labeled datasets. In this work, we...

Abstract Secondary headache, fever, and upper motor neuron signs following facial herpes zoster during childhood should alert clinicians to the possibility of central nervous system complications varicella‐zoster virus infection.

Facial expression recognition is a very meaningful and challenging research topic it has been widely used in many problems the artificial intelligence era. Such as human computer interaction, intelligent family robot, patient diagnosis, driver safety. In this paper, we proposed new approach for facial based on ELM(Extreme Learning Machine). Traditional ELM famous simple structure high accuracy both classification regression problems. However, number of neurons hard to determine given...

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