A5003344656- Nasal Surgery and Airway Studies
- Parkinson's Disease Mechanisms and Treatments
- Cleft Lip and Palate Research
- Reconstructive Facial Surgery Techniques
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Congenital Ear and Nasal Anomalies
- Reconstructive Surgery and Microvascular Techniques
- Nerve Injury and Rehabilitation
- Nerve injury and regeneration
- Stroke Rehabilitation and Recovery
- Craniofacial Disorders and Treatments
- Elbow and Forearm Trauma Treatment
- Cerebral Palsy and Movement Disorders
- Sinusitis and nasal conditions
- Spinal Cord Injury Research
- Facial Rejuvenation and Surgery Techniques
- Neurogenetic and Muscular Disorders Research
- Diabetic Foot Ulcer Assessment and Management
- Surgical site infection prevention
- Mesenchymal stem cell research
- Congenital limb and hand anomalies
- Knee injuries and reconstruction techniques
- Wound Healing and Treatments
- Botulinum Toxin and Related Neurological Disorders
Shanghai Jiao Tong University
2022-2025
Shanghai Ninth People's Hospital
2021-2025
First Affiliated Hospital of Jiangxi Medical College
2024
Huashan Hospital
2018-2021
Fudan University
2018-2021
Dongguan People’s Hospital
2020
First Affiliated Hospital of Nanchang University
2020
Nanchang University
2020
Jiangxi Provincial People's Hospital
2018-2020
Jiangxi Maternal and Child Health Hospital
2020
We describe a general approach to produce bone and cartilaginous structures utilizing the self-regenerative capacity of intercostal rib space treat deformed metacarpophalangeal joint microtia. Anatomically precise 3D molds were positioned on perichondro-periosteal or perichondral flap without any other exogenous elements. find anatomically metacarpal head auricle constructs within implanted after 6 months. The regenerated was used successfully surgically repair joint. Auricle reconstructive...
Abstract Background Adipose-derived stem cells (ADSCs)-assisted fat grafting has emerged as a widely used procedure for breast reconstruction post mastectomy and aesthetic augmentation. Given the limited cases of cancer following grafting, oncological safety this remains controversial. Methods The effects ADSCs on oncogenic features premalignant MCF-10AT were investigated using co-culture xenograft models. We further evaluated malignancy-promoting effect in 7,12-Dimethylbenz(a)anthracene...
Abstract Parry–Romberg syndrome is a rare craniofacial disorder which characterized by progressive facial atrophy. The etiology and pathogenesis of the disease are not known. Herein, we report genetic variants in patient with this disease. A 25-year-old woman was diagnosed according to her clinical manifestation, presented typical unilateral soft tissue Using peripheral blood samples, Whole exome sequencing (WES) conducted on parents. Variant loci genes were validated Sanger twin sister who...
The study was to explore whether the 3-dimensional printing guiding plate system could facilitate modified procedure for arthroscopic treatment of nondisplaced scaphoid nonunion.Patients, diagnosed with nonunion without displacement, were randomly assigned into two groups. In Group A, used fixation during surgery. B, performed intra-operative fluoroscopy. bone operation time recorded patients evaluated before surgery and followed-up after six post-operative months, including motion ratio,...
Abstract Current strategies for the chronic stage of spinal cord injury (SCI) had seen little progress. In this report, we present use contralateral L5 nerve transfer treatment incomplete SCI patients with unilateral lower limb dysfunction in two male patients. One was diagnosed L2 vertebral fracture and dislocation combined coni medullaris 10 months prior, other T6 T7 fractures 24 prior. The were treated decompression surgery within hr after injury. reached a recovery plateau 6–8...
We previously reported transferring seventh cervical (C7) nerve from unaffected side to affected in patients with spastic hemiplegia due chronic cerebral injury, improve function and reduce spasticity of paralyzed upper limb. In the clinics, some also changes their lower limb, which could not be detected by routine physical examinations. Pennation angle muscle can indirectly reflect condition spasticity. The purpose this study was evaluate whether limb procedure may affect using...
Objective To assess the effect and complications of tibial cortex transverse distraction (TCTD) in treating diabetic foot ulcers draw attention to concerning issues this procedure. Methods This case series included 30 patients with from four centers. The had not healed after >6 months. then underwent TCTD combined other procedures (debridement, vacuum sealing drainage, others). All were followed up for >12 months postoperatively. Results Three amputation because aggravated infections....
Background: The repair of nasal alar defects is challenging for plastic surgeons, and there currently no standard operation. Herein, the authors reported clinical outcomes a nasofacial groove pedicled flap reconstruction defect. Methods: This retrospective study included patients who underwent defect between January 2018 June 2020. Photographs facial postures were taken before after surgery to record surgical results patients. patient’s medical history was reviewed retrospectively....
Obvious scar and deformities are commonly observed with incision anterior to the alar-facial groove in alar excision surgery. The authors explored modified sill correct wide base flare synchronously decreased incident of unacceptable Asian patients.The conducted a retrospective cohort study including 52 consecutive patients undergoing this Contrary previous studies, for was located closed by intracutaneous suture. Scars were assessed visual analog scale Stony Brook Scar Evaluation Scale....
Background: Restricted ventilation is common after rhinoplasty with an endogenous extension stent. The authors proposed exogenous stent concept for Asian patients to avoid this problem. Herein, we introduce innovative in Asians, which application of concept. Methods: An L-shaped expanded polytetrafluoroethylene hand-carved, and the long arm placed at nose back improve flatness nose, while short supports nasal column raise tip. prosthesis does not occupy volume therefore theoretically affect...
Abstract Background Flap transplantation is often needed for soft tissue defects of the fingers that cannot be closed directly. Sensory reconstruction important patients to recover feelings. In this study, we report clinical outcomes using free neurovascular transverse wrist crease flap repairing finger from multiple centers. Methods This case series includes 72 consecutive with between June 2013 and 2016 A radial artery superficial palmar branch flap, named was designed reconstruct...
Current strategies for correcting alar retraction mainly include cartilage grafting and composite grafting, which are relatively complicated may produce injury to the donor site. Herein, we introduce a simple effective external Z-plasty technique in Asian patients with poor skin malleability.Twenty-three were presented malleability, they very concerned about shape of nose. These undergoing surgery analyzed retrospectively. In this surgery, no grafts needed, location was according highest...
Endogenous α-synuclein (α-Syn) is involved in many pathophysiological processes the secondary injury stage after acute spinal cord (SCI), and mechanism governing these functions has not been thoroughly elucidated to date. This research aims characterize effect of α-Syn knockdown on transcriptional levels SCI determine mechanisms underlying activity based RNA-seq.The establishment a rat model lentiviral vector-mediated Sprague-Dawley rats with T3 contusion (LV_SCI group). The results RNA-seq...
According to Tessier classification, number 1 and 2 craniofacial clefts involve the nasal ala. Congenital cleft is not common difficult for reconstruction. Notches in medial one-third of either ala are typical manifestations these patients. Herein, we introduce a alar rim triangular flap, which indeed local treatment isolated due congenital deformities pediatric patients.The authors conducted retrospective cohort study including 10 consecutive patients undergoing this surgery. This flap...
Chronic refractory wounds were common and the treatments complicated for burn plastic surgeons. This study was to investigate bacterial distribution characteristics drug resistance of chronic wound secretions.The authors retrospectively analyzed 425 patients with infection. The results culture secretions sensitivity test analyzed. Further, location area divided into 4 regions, difference between different regions analyzed.The cultured 401 strains, including 206 gram-positive bacteria...
Hearing loss is one of the most common neurosensory disorders in humans, and above half hearing caused by gene mutations. Among more than 100 genes that cause non-syndromic loss, myosin VI (MYO6) typical terms complexity underlying mechanisms, which are not well understood. In this study, we used both knock-out (Myo6-/-) point mutation (Myo6C442Y) mice as animal models, performed whole-cell patch-clamp recording capacitance measurement inner hair cells (IHCs) cochlea, sought to reveal...
Objective To evaluate the feasibility of locked intramedullary nailing, rather than locking plate fixation combined with fibular allograft augmentation, for initial varus proximal humeral fractures. Methods This prospective pilot study enrolled patients fractures that were treated a nail. Radiography was performed to fracture healing. Data about visual analogue scale (VAS) pain score, Constant Shoulder Score (CSS), Disabilities Arm, and Hand (DASH) American Elbow Surgeons (ASES) score...
Abstract Large eyelid defect after excision of malignancies or trauma is difficult to reconstruct due special structure and function the eyelid. In this study, we aimed present outcomes subcutaneous pedicled propeller flap for reconstructing large trauma. A retrospective review patients diagnosed with trauma, undergoing defect, was conducted at our hospital. The clinical data were collected analyzed. total 15 included in cases series. Nine basal cell carcinoma, 3 epidermoid All defects...
Pseudomonas aeruginosa is an opportunistic pathogen, and because of its specificity, treatments appear tricky in postrhinoplasty infections with internal implants. This study summarizes the clinical characteristics treatment this type to provide some reference for work.We retrospectively analyzed 10 patients who were diagnosed a nasal infection P. after implant augmentation. The results bacterial culture drug sensitivity test patients' wound secretions summarized analyzed. We treatments, we...