- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Reconstructive Surgery and Microvascular Techniques
- Facial Rejuvenation and Surgery Techniques
- Congenital Ear and Nasal Anomalies
- Bone fractures and treatments
- Bone Tissue Engineering Materials
- Temporomandibular Joint Disorders
- Tissue Engineering and Regenerative Medicine
- Organ and Tissue Transplantation Research
- Periodontal Regeneration and Treatments
- Obstructive Sleep Apnea Research
- Advanced Optical Network Technologies
- Optical Network Technologies
- Craniofacial Disorders and Treatments
- Knee injuries and reconstruction techniques
- Neuroscience and Neuropharmacology Research
- Cardiac Arrest and Resuscitation
- Breast Implant and Reconstruction
- Cerebrovascular and Carotid Artery Diseases
- Kidney Stones and Urolithiasis Treatments
- Software-Defined Networks and 5G
- Dental Implant Techniques and Outcomes
- Sinusitis and nasal conditions
Shanghai Ninth People's Hospital
2016-2025
Shanghai Jiao Tong University
2012-2025
National Natural Science Foundation of China
2016-2020
China Medical University
2007-2016
Czech Radio
2008
Brigham and Women's Hospital
2005
University of North Texas
2003-2004
University of North Texas Health Science Center
2003-2004
The People's Hospital of Guangxi Zhuang Autonomous Region
2004
Increased production of reactive oxygen species contributes to the etiology diabetes complications. Pathophysiological stimuli that increase oxidative stress upregulate heme oxygenase (HO)-1, a cytoprotective heme–degrading enzyme. We hypothesized HO-1 may be important in myocardial injury is exacerbated by diabetes. To test this hypothesis, left anterior descending coronary arteries nondiabetic and diabetic wild-type (HO-1+/+) null (HO-1–/–) mice were ligated for 1 h followed 24...
We describe a general approach to produce bone and cartilaginous structures utilizing the self-regenerative capacity of intercostal rib space treat deformed metacarpophalangeal joint microtia. Anatomically precise 3D molds were positioned on perichondro-periosteal or perichondral flap without any other exogenous elements. find anatomically metacarpal head auricle constructs within implanted after 6 months. The regenerated was used successfully surgically repair joint. Auricle reconstructive...
As WDM technology matures and multicast applications become increasingly popular, supporting at the layer becomes an important yet challenging topic. In this paper, we study constrained routing in networks with sparse light splitting, i.e., where some switches are incapable of splitting (or copying data optical domain). Specifically, propose four algorithms, namely, Re-route-to Source, Re-route-to-Any, Member-First, Member-Only. Given network topology, membership information, capability...
Protective effects of estrogen on nerve cells including retinal neurons have been described previously. However, subcellular synaptic connectivity in mild ischemia more closely resembling ischemic conditions found diabetic or sickle cell retinopathy and stenosis the carotid artery not identified. The present study quantitatively analyzed administration connections ganglion layer (GCL) retina.Staining Vesl-1L/Homer 1c (V-1L) immunoreactivity TUNEL cytochemistry were used to quantify...
Supporting WDM multicasting in an IP over network poses interesting problems because some switches may be incapable of switching incoming signal to more than one output interface. An approach based on wavelength-routing, which constructs a multicast forest for each session so that multicast-incapable do not need multicast, was proposed and evaluated previously. Such requires global knowledge the layer. In this paper, we study under framework multiprotocol label (MPLS) using optical...
BACKGROUND Botulinum toxin type A (BTX-A) is widely used for the clinical treatment of masseteric hypertrophy. Until now, few reports have discussed how to prolong duration its effectiveness. OBJECTIVE This study evaluated that purposely adjusting masticatory movements possible postponing masseter muscle rehypertrophy. METHODS Ninety-eight patients were randomly and equally divided into 2 groups, 35 U BTX-A per side was injected masseters. The thickness volume muscles measured by ultrasound...
Abstract Parry–Romberg syndrome is a rare craniofacial disorder which characterized by progressive facial atrophy. The etiology and pathogenesis of the disease are not known. Herein, we report genetic variants in patient with this disease. A 25-year-old woman was diagnosed according to her clinical manifestation, presented typical unilateral soft tissue Using peripheral blood samples, Whole exome sequencing (WES) conducted on parents. Variant loci genes were validated Sanger twin sister who...
As WDM technology matures, IP over multicast will become a challenging new topic. Supporting at the layer provides additional advantages, but also raises many issues that do not exist in multicast. For example, limitation on light splitting capability of switches is one major difficulty multicast, and addition, limitations both wavelength conversion optical buffer space may affect routing as well. In this paper, we focus problem, i.e. how to construct trees based protocols. More...
Background Various techniques for the aesthetic correction of short noses have been described, but selection adequate graft material remains controversial. Previous reports mainly focused on application septal cartilage or alloplastic materials nose elongation, lengthening effect is often unsatisfactory severe noses. We propose costal as an alternative treatment noses, describe technique, and discuss outcomes, patient selection, complications based our 15-year experience. Methods From...
Abstract The aim of this project was to construct vascularized tissue‐engineered living bone with an autologous vascular network by means a rabbit bioreactor in vivo. key components the vivo for formation were tibial periosteum and saphenous bundle. Beta‐tricalcium phosphate (β‐ TCP ) scaffolds implanted into (vascular pedicle implantation encapsulation). At 4 weeks postsurgery, new mainly “cartilage‐bone inducing” inner periosteum, primarily seen outer aspects scaffold some amount middle...
Background We developed a novel pedicled DIEP flap model in rat to explore the possible remedy for distal necrosis of flap. Methods A deep inferior epigastric perforator (DIEP) flap, based on second right cranial (P2) as main pedicle, was elevated 48 Sprague-Dawley rats. The rats were randomized into 4 groups: group I, left P2 remaining intact supercharging; II, artery alone kept III, vein IV, no supercharging. Transcutaneous oxygen pressure (TcPO2) and transcutaneous carbon dioxide (TcPCO2)...
Short nose elongation is a relatively common rhinoplasty procedure, especially in Asia. The selection of the adequate graft material challenging. Previous reports have described application expanded polytetrafluoroethylene (ePTFE) for dorsal augmentation rhinoplasty, but studies using ePTFE are lacking. We propose as an alternative treatment short noses, describe technique, and discuss outcomes, patient selection, complications based on our 14-year experience.From February 2003 to December...
Background The aim of the present study was to evaluate potential psychosocial factors that impact Chinese female breast cancer patients select reconstruction (BR), and connection outcomes with their satisfaction BR. Methods A total 264 mastectomy were recruited from 2012 2014. All informed BR options at first visit. Personal medical profiles collected. Body image, self-esteem, depression anxiety assessed using validated scales. Patients who selected undergo after visit followed up for six...
Background: The repair of nasal alar defects is challenging for plastic surgeons, and there currently no standard operation. Herein, the authors reported clinical outcomes a nasofacial groove pedicled flap reconstruction defect. Methods: This retrospective study included patients who underwent defect between January 2018 June 2020. Photographs facial postures were taken before after surgery to record surgical results patients. patient’s medical history was reviewed retrospectively....
PURPOSE: To investigate the effect of remote ischemic post-conditioning (RIPoC) against ischemia-reperfusion (I/R) injury on flaps rats. METHODS: Sprague-Dawley rats were randomized into Sham, Control, RIPoC1 and RIPoC2 groups. All animals submitted to a 5×4 cm superficial inferior epigastric artery flap. Eight hours flap ischemia was induced two protocols limb RIPoC applied. Tissue MDA level SOD activity in 24-h reperfusion assessed. Flap survival assessed 7 days postoperatively. RESULTS:...
Reconstruction of large mandibular defects is complex and challenging. The authors aimed to individually self-generate a vascularized bone construct for autologous transplantation without the use exogenous additives based on concept guided self-generation. Using computer-aided design manufacturing size goat was reconstructed in 3 dimensions. Its negative mold printed from hydroxylapatite temporarily embedded into costal periosteum along with contralateral demineralized matrix scaffold as...
Tissue engineering based on cell seeding, bioscaffolds, and growth factors has been widely applied for the reconstruction of tissue defects. Recent progress fueled in vivo techniques becoming hot topics regenerative medicine reconstructive surgery. To improve efficacy engineering, we here investigated roles factors, microenvironment (IM) regeneration. Bone marrow-derived stem cells, allogeneic demineralized bone matrix as bioscaffold, factor morphogenetic protein 2/transforming factor, IM...
Obvious scar and deformities are commonly observed with incision anterior to the alar-facial groove in alar excision surgery. The authors explored modified sill correct wide base flare synchronously decreased incident of unacceptable Asian patients.The conducted a retrospective cohort study including 52 consecutive patients undergoing this Contrary previous studies, for was located closed by intracutaneous suture. Scars were assessed visual analog scale Stony Brook Scar Evaluation Scale....
Background: Restricted ventilation is common after rhinoplasty with an endogenous extension stent. The authors proposed exogenous stent concept for Asian patients to avoid this problem. Herein, we introduce innovative in Asians, which application of concept. Methods: An L-shaped expanded polytetrafluoroethylene hand-carved, and the long arm placed at nose back improve flatness nose, while short supports nasal column raise tip. prosthesis does not occupy volume therefore theoretically affect...
Inositol (1,4,5)-trisphosphate receptors (IP3Rs) contribute substantially to cytosolic free calcium ion (Ca2+) concentration transients and thereby modulate neuronal function. The present study was undertaken determine the contribution of IP3Rs function rod bipolar cells in retina.Immunoreactivity for from mouse retinas detected by immunocytochemical methods. Intracellular Ca2+ concentrations were optically recorded acutely isolated cells, biophysical properties analyzed with single channel...