- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Cleft Lip and Palate Research
- Advanced biosensing and bioanalysis techniques
- Facial Rejuvenation and Surgery Techniques
- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Economic and Financial Impacts of Cancer
- Cancer survivorship and care
- Histone Deacetylase Inhibitors Research
- Digital Imaging in Medicine
- Cancer-related molecular mechanisms research
- Congenital Ear and Nasal Anomalies
- RNA modifications and cancer
- Cancer Immunotherapy and Biomarkers
- Anatomy and Medical Technology
- Biosensors and Analytical Detection
- Cardiac Imaging and Diagnostics
- Biosimilars and Bioanalytical Methods
- Immune cells in cancer
Sun Yat-sen University Cancer Center
2023-2025
Linyi University
2024-2025
Affiliated Hospital of Qingdao University
2017-2025
Sun Yat-sen University
2020-2025
Wuhan University of Science and Technology
2024-2025
Qingdao University
2017-2025
Shanghai Ninth People's Hospital
2021-2025
Shanghai Jiao Tong University
2018-2025
China Agricultural University
2021-2025
First Affiliated Hospital of Harbin Medical University
2023-2025
Surgical-site infection causes devastating reconstructive failure in implant-based breast reconstructions. Large national database studies offer insights into complication rates, but only capture outcomes within 30 days postoperatively. This study evaluates both early and late surgical-site immediate reconstruction identifies predictors.As part of the Mastectomy Reconstruction Outcomes Consortium Study, 1662 reconstructions 1024 patients were evaluated for versus infection. Early was defined...
The ideal timing of postmastectomy radiation therapy (PMRT) in the setting two-stage implant-based breast reconstruction remains unclear. In this cohort study, authors sought to determine whether complication rates differed between patients who received PMRT following tissue expander placement (TE-XRT) and those after exchange for permanent implants (Implant-XRT) utilizing using prospective, multicenter data.Eligible Mastectomy Reconstruction Outcomes Consortium study from 11 institutions...
We describe a general approach to produce bone and cartilaginous structures utilizing the self-regenerative capacity of intercostal rib space treat deformed metacarpophalangeal joint microtia. Anatomically precise 3D molds were positioned on perichondro-periosteal or perichondral flap without any other exogenous elements. find anatomically metacarpal head auricle constructs within implanted after 6 months. The regenerated was used successfully surgically repair joint. Auricle reconstructive...
This study was to investigate the potential mechanisms of treatment with metformin (Met) combined kaempferol (Kae) against postmenopausal osteoporosis. Experiments were conducted in both ovariectomy (OVX)-induced osteoporosis rats and vitro using RAW264.7 cells, MC3T3-E1 HUVECs. Results demonstrated therapeutic effect Met Kae on In vivo, alone combination treatments enhanced tibial trabecular microstructure, bone mineral density (BMD), mechanical properties OVX without causing hepatotoxicity...
Gastric cancer (GC) is one of the most commonly occurring cancers, and metabolism-related genes (MRGs) are associated with its development. Transcriptome data relevant clinical were downloaded from The Cancer Genome Atlas Gene Expression Omnibus databases, we identified 194 MRGs differentially expressed between GC adjacent nontumor tissues. Through univariate Cox lasso regression analyses 13 potential prognostic (PDEMRGs). These PDEMRGs (CKMT2, ME1, GSTA2, ASAH1, GGT5, RDH12, NNMT, POLR1A,...
Abstract Ribozymes are excellent systems in which to study ‘sequence - structure function’ relationships RNA molecules. Understanding these may greatly help structural modeling and design of functional structures some modules could be repurposed molecular design. At present, there is no comprehensive database summarising all the natural ribozyme families. We have therefore created Ribocentre, a that collects together sequence, mechanistic data on 21 This includes available information...
<h3>Importance</h3> Although advance care planning is known to increase patient and caregiver satisfaction, its association with health utilization not well understood. <h3>Objective</h3> To examine the between billed encounters subsequent among seriously ill patients. <h3>Design, Setting, Participants</h3> This retrospective cohort study conducted from October 1, 2015, May 31, 2018, used a national commercial insurance claims database retrieve data 18 484 Medicare Advantage members 65 years...
Tumor-derived small extracellular vesicles (sEVs) play an essential role in reprogramming the tumor microenvironment. Metabolic is prerequisite for M2 polarization of tumor-associated macrophages (TAMs). This phenotype closely related to immune dysfunction CD8+ T cells and subsequent progression. study evaluates laryngeal squamous cell carcinoma cell-derived (LSCC-sEVs) TAMs dysfunction, delineates underlying mechanisms. Human leukemia monocyte line (THP-1) was induced differentiate into M0...
Background The demand for frailty care is continuously increasing in hospitalized tumor patients with the aging of population. Nurses are primary providers but research on exploring their behavior and associated factors limited. This study aims to describe current situation behaviors oncology nurses explore influencing behaviors. Methods From August 1, 2023, March 31, 2024, this cross-sectional was conducted among from oncology-related departments 5 Secondary A (mid-tier hospitals providing...
Abstract The lipid accumulation associated with diabetes causes continuous liver and kidney damage. Laminaria japonica polysaccharide (fucoidan) has been shown to regulate the disorder in metabolism caused by diabetes. Herein, we established a mellitus (DM) rat model through high‐fat high‐sugar diet combined streptozotocin. An automatic biochemical analyzer was used detect serum content, hematoxylin eosin, Masson, periodic acid‐silver‐methenamine, Oil Red O staining were observe changes...
ABSTRACT Aim(s) To determine the correlation between preoperative health education and emotions of lung cancer patients, artificial intelligence software was used. Design This a cross‐sectional study. Methods study included 210 patients from Sun Yat‐sen University Cancer Center examined impact on patient using an AI‐based emotion analysis tool. Results indicated significant relationship tone emotional content materials emotions. Specifically, educational with explanatory negative sentiment...
Abstract Background Adipose-derived stem cells (ADSCs)-assisted fat grafting has emerged as a widely used procedure for breast reconstruction post mastectomy and aesthetic augmentation. Given the limited cases of cancer following grafting, oncological safety this remains controversial. Methods The effects ADSCs on oncogenic features premalignant MCF-10AT were investigated using co-culture xenograft models. We further evaluated malignancy-promoting effect in 7,12-Dimethylbenz(a)anthracene...
Background Optimizing the patient experience is a central pillar in healthcare quality. Although this may be recognized as important breast reconstruction, surgeons are often unaware of how well they and members their team achieve goal. The objective our study was to evaluate satisfaction with care multicenter, prospective cohort patients undergoing reconstruction. Specifically, we sought determine which aspects might most amenable quality improvement. Methods As part Mastectomy...
The aim of the present study was to investigate protective mechanisms and identify effects isoquercetin on myocardial infarction in a rat model acute (AMI). Isoquercetin ameliorated infarct size, creatine kinase (CK), CK‑MB lactic dehydrogenase activity inhibited inflammation, oxidative stress heart cell apoptosis with AMI. increased endothelial nitric oxide synthase, reduced inducible synthase levels suppressed Toll-like receptor 4‑nuclear factor (TLR4‑NF)‑κB signaling pathway Overall, AMI...