- Parkinson's Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cerebral Venous Sinus Thrombosis
- Neurological and metabolic disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Gut microbiota and health
- Long-Term Effects of COVID-19
- Infectious Encephalopathies and Encephalitis
- Dysphagia Assessment and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Pharmacological Effects and Toxicity Studies
- Stroke Rehabilitation and Recovery
- IgG4-Related and Inflammatory Diseases
- Neurosurgical Procedures and Complications
- Facial Nerve Paralysis Treatment and Research
- Ginger and Zingiberaceae research
- Biosimilars and Bioanalytical Methods
- Sarcoidosis and Beryllium Toxicity Research
- Cerebrovascular and genetic disorders
- Obesity, Physical Activity, Diet
- Neurological Complications and Syndromes
- Fetal and Pediatric Neurological Disorders
Manipal Academy of Higher Education
2018-2025
National Institute of Technology Karnataka
2024
Kasturba Medical College, Manipal
2017-2024
University of California, Los Angeles
2024
John Radcliffe Hospital
2024
University of Oxford
2024
University of Nevada, Reno
2024
Jain University
2024
M. S. Ramaiah Dental College and Hospital
2023
Bioprocessing Technology Institute
2021
Maximal voluntary contraction (MVC) using a handgrip dynamometer was assessed in seventy-two young adult males. The subjects were divided into two groups on the basis of BMI 18.5 kg/m2. with < kg/m2 (n 38) further an underweight (UW; n 20) group and chronically energy-deficient (CED; 18) group. CED had significantly lower MVC (30.1, SD 5.9 kg) than either well-nourished controls (BMI > kg/m2: 39.8, 5.8 or (37.6, 4.9 kg). differences between UW persisted even after corrected for forearm...
ABSTRACT Objective: To determine the clinical characteristics and treatment outcomes in patients with trigeminal neuralgia a tertiary care setting. Material Methods: The data of diagnosed over nine-year period this center from archives Medical Records Department were included. Two observers documented specially designed proforma. A p-value <0.0S was considered statistically significant. comparison categorical variables done using Chi-square/Fisher exact test. continuous Mann-Whitney U...
Central nervous system infections (CNSI) are serious life-threatening conditions caused by bacteria, viruses, fungi, and parasites lead to high morbidity mortality worldwide. Therefore, rapid identification of causative organisms appropriate treatment important. The traditional methods time-consuming lack sensitivity specificity. Although culture method is gold standard for CNSI, it microbiology reporting requires several days. Multiplex PCR assays can detect multiple pathogens...
Acute management of ischemic stroke involves thrombolysis within 4.5 h. For a successful outcome, early recognition stroke, transportation to the hospital emergency department immediately after timely imaging, proper diagnosis, and h is paramount importance.To analyze obstacles for in acute patients.The study was conducted tertiary care center South India. A total hundred consecutive patients who were not thrombolysed, but otherwise fulfilled criteria evaluated prospectively various factors...
Objectives: Recent advancement in understanding neurological disorders has revealed the involvement of dysbiosis gut microbiota pathophysiology Parkinson’s disease (PD). We sequenced microbial DNA using fecal samples collected from PD cases and healthy controls (HCs) to evaluate role microbiota. Methods: Full-length bacterial 16S rRNA gene sequencing was performed amplified polymerase chain reaction (PCR) products on GridION Nanopore sequencer. Sequenced data were analyzed web-based tools...
Agrawal, Sumedh S.; Shetty, Nikith A.; Shenoy, Nisha; Prabhu, Arvind N.; Pai, Aparna R. Author Information
Visual symptoms in pregnancy are ominous. The spectrum of ocular seen pre-eclampsia includes blurring vision, scotoma, hemianopia and even total cortical blindness. Diplopia, though rare has also been reported cases occurs due to pathological changes affecting the 6th cranial nerve. Ocular usually regress after delivery but occasionally may present postpartum period. We a case 34-year-old lady with severe at 31 weeks gestation diplopia presenting seven days post caesarean section. No...
Dengue infection can cause various effects on the central and peripheral nervous systems. Direct neurotropism immunological mechanisms are responsible for most such neurological manifestations. We present case of a 64-year-old woman with rapidly progressive dementia seizures following dengue infection.
Abstract Background Anti-TNF therapy is established as a mainstay in IBD management. Recent data raise controversies regarding efficacy of these agents, sustainability response, and identification factors that may influence outcomes, including dose escalation need for long-term concurrent immunosuppression (Lancet Gastro.Hep.2019;4:341). Methods We report retrospective cohort study 699 patients on anti-TNF at our centre between 2005-2022. Clinical were obtained from patient records pharmacy...
This paper introduces and analyses the performance of Petri net model created to simulate a traffic control system using Additive Increase Multiplicative Decrease (AIMD) algorithm. The was designed TimeNET [1] tool. evaluated by analysing Reachability Graph generated Depth First Search (DFS) Backtracking based Several criteria such as Stability, Boundedness, Deadlock, etc. were verified our proposed then validated through C++ code ensure it performs correctly under different situations. All...
Abstract BACKGROUND Choroid plexus papilloma (CPP) is a benign intraventricular lesion associated with hydrocephalus and ventricular outflow obstruction. However, the molecular mechanism by which cerebrospinal fluid (CSF) produced choroid (CP), or CSF production altered in setting of CPP to cause hydrocephalus, unknown. METHODS A PRISMA systematic literature review was conducted identify gene targets production. Primary tissue samples CP from same patient were obtained, expression target...
Serotype M28 isolates of the bacterial pathogen group A Streptococcus (GAS; pyogenes), but not other serotypes, have a nonrandom association with cases puerperal sepsis, life-threatening infection that can occur in women following childbirth. In prior studies, we established RD2, pathogenicity island present all GAS mostly absent from is factor M28-puerperal sepsis association. Here, identified significant reduction RD2 conjugation frequency inter-serotype assays relative to intra-serotype...
Parkinson’s disease (PD) is a progressive neurodegenerative disorder mostly affecting the elderly population. Nutritional status, dietary habits, and physical activity are closely associated with PD clinical symptoms. Based on scientific evidence, lifestyle adjustments being considered as therapy approaches in various chronic diseases. Dietary modifications an additional treatment strategy for managing motor non-motor symptoms PD. This review focuses latest nutritional interventions protein...
Introduction and Aim: Parkinson’s Disease (PD) is a multifactorial neurodegenerative disorder with ever-changing motor nonmotor symptoms. treatment modified accordingly the progression of disease. The present study was carried out to understand symptoms reported by PD subjects in different phases disease.
 
 Materials Methods: Demographic clinical details were obtained using questionnaires evaluate frequency severity various experienced subjects.
 Results: Ageing strongly...
Background: The habit of eating more sugary drinks and foods with high in trans fats excessive saturated fatty foods, when the person is stress has an effect on individual’s weight. Objectives: To evaluate body mass index (BMI) determine its association abnormal oral habits 6–12-year-old school-going children. Materials Methods: 46 schools were selected based simple random sampling technique all children who aged between 6 12 years included study. Among 5525 screened, 1665 (30.13%) had...