A5041837108- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Spectroscopy and Chemometric Analyses
- Metabolomics and Mass Spectrometry Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Mass Spectrometry Techniques and Applications
- Petroleum Processing and Analysis
- Analytical chemistry methods development
- Pharmaceutical and Antibiotic Environmental Impacts
- Liver Disease Diagnosis and Treatment
- Sphingolipid Metabolism and Signaling
- Crystallization and Solubility Studies
- Drug Solubulity and Delivery Systems
- Chromatography in Natural Products
- Industrial Vision Systems and Defect Detection
- Essential Oils and Antimicrobial Activity
- Nonlinear Optical Materials Research
- Wood Treatment and Properties
- Toxic Organic Pollutants Impact
- Hydrocarbon exploration and reservoir analysis
- Water Quality Monitoring and Analysis
- Wood and Agarwood Research
- Tryptophan and brain disorders
- bioluminescence and chemiluminescence research
- Fault Detection and Control Systems
University of Copenhagen
2018-2020
Universidade Estadual de Campinas (UNICAMP)
2012-2020
Forensic investigations of oil spills aim to find the responsible source(s) spill. Oil weathering processes change chemical composition spilled and make matching spill samples potential sources difficult. Diesel cases are more challenging, because biomarkers recalcitrant long-term absent. We developed tested a new method for analysis diesel using two-dimensional gas chromatography–high resolution mass spectrometry (GC × GC – HRMS) 2D-CHEMSIC (2-Dimensional CHEMometric Selected Ion...
Atypical antipsychotics are widely used to manage schizophrenia symptoms. However, these drugs can induce deleterious side effects, such as MetS, which associated with an increased cardiovascular risk patients. Lipids play a central role in this context, and changes lipid metabolism have been implicated schizophrenia's pathobiology. Furthermore, recent evidence suggests that lipidome may be related antipsychotic treatment response. The aim of study was evaluate the blood plasma samples...
Abstract Background Sediments are sinks for organic micropollutants, which traditionally analysed by gas chromatography–mass spectrometry (GC–MS). Although GC–MS and GC–tandem MS (MS/MS) preferred target screening, they provide only limited chromatographic resolution nontarget screening. In this study, a comprehensive two-dimensional GC–high-resolution method (GC × GC–HRMS) was developed screening source identification of micropollutants in sediments from an urban channel adjacent lake...
This is the first study to identify lipidomic markers in plasma associated with response of acutely ill schizophrenia patients specific antipsychotic treatments. The population included 54 treated antipsychotics for 6 weeks. Treatment led significant improvement positive and negative symptoms 34 little or no 20 patients. In addition, 37 showed an increase body mass index after week treatment period, consistent effects on metabolism association such symptom improvement. Profiling samples...
DESCRIPTION, OPERATION AND APLICATIONS.Multivariate Curve Resolution with Alternating Least Squares (MCR-ALS) is a resolution method that has been efficiently applied in many different fields, such as process analysis, environmental data and, more recently, hyperspectral image analysis.When to second order (or three-way data) arrays, recovery of the underlying basis vectors both measurement orders (i.e.signal and concentration orders) from matrix can be achieved without ambiguities if...
The knowledge about the organic matter predominant depositional paleoenvironment in which crude oils gave rise is essential for extensive understanding of their corresponding geochemical features. This task laborious and conventionally performed through search classical biomarkers contained specific saturate, aromatic, resin, asphaltene (SARA) fractions oils. In this work, well-established analytical technique comprehensive two-dimensional gas chromatography–quadrupole mass spectrometry (GC...
The current methodology used in quality control of Ecuadorian beverages such as Pájaro azúl, Puro and Pata de vaca is carried out by using conventional gas chromatography; however, it does not allow the fingerprinting these spirit their possible cases adulteration. In order to overcome this drawback, comprehensive two-dimensional chromatography–mass spectrometry (GC × GC–MS) was combined with multivariate data analysis, revealing that compounds like citronellal, citronellol, geraniol, methyl...
The enhanced analytical performance of comprehensive two-dimensional gas chromatography–mass spectrometry (GC×GC–MS) has demonstrated significant advantages for geochemical investigations crude oils. However, the conventional analysis oils based on diagnostic ratios from specific petroleum biomarkers can be more laborious and time-consuming GC×GC. Additionally, extraction biomarker patterns is analyst-dependent; therefore, discovery less evident and/or new challenging. This work introduces...
A new algorithm that combines spectral interval selection using genetic and classical least squares (GA-iCLS) is presented for the prediction of active pharmaceutical ingredients excipients in various solid dosage forms from near infrared chemical imaging data. The based on CLS approach, selecting best wavenumber intervals unfolded hyper-cube each sample (D), pure-compound reference spectra (S), wherein pixel-to-pixel capability compounds, obtained by C = DS T (SS ) −1 , optimised samples....
Abstract Atypical antipsychotics are widely used to manage schizophrenia symptoms. However, these drugs can induce deleterious side effects, such as MetS, which associated with an increased cardiovascular risk patients. Lipids play a central role in this context, and changes lipid metabolism have been implicated schizophrenia’s pathobiology. Furthermore, recent evidence suggests that lipidome may be related antipsychotic treatment response. The aim of study was evaluate the blood plasma...