A5039435519- Endodontics and Root Canal Treatments
- Bone Tissue Engineering Materials
- Bone and Dental Protein Studies
- dental development and anomalies
- Bone Metabolism and Diseases
- Dental Radiography and Imaging
- Periodontal Regeneration and Treatments
- Dental Trauma and Treatments
- Oral and Maxillofacial Pathology
- Bone health and treatments
- Mesenchymal stem cell research
- Dental materials and restorations
- Hydrogen's biological and therapeutic effects
- Caveolin-1 and cellular processes
- FOXO transcription factor regulation
- Curcumin's Biomedical Applications
- Anesthesia and Neurotoxicity Research
- Magnetic Properties and Applications
- Immune Response and Inflammation
- Cancer Cells and Metastasis
- Polymer Surface Interaction Studies
- Magnetic Properties of Alloys
- Orthopaedic implants and arthroplasty
- Dental Erosion and Treatment
- Dental Anxiety and Anesthesia Techniques
Kyung Hee University Dental Hospital
2015-2024
Kyung Hee University
2014-2024
Hankyong National University
2024
Dankook University
2015
University of California, Los Angeles
2014
Gold nanoparticles (GNPs) have been previously reported to inhibit osteoclast (OC) formation. However, previous research only confirmed the osteoclastogenesis inhibitory effect under in vitro conditions. The aim of this study was develop a therapeutic agent for osteoporosis based on utilization GNPs and confirm their both vivo. We prepared β-cyclodextrin (CD) conjugated (CGNPs), which can form inclusion complexes with curcumin (CUR–CGNPs), used these investigate effects receptor activator...
Background/Aims: Mussel-inspired polydopamine (PDA) is known to be an effective bioadhesive and bioactive material for controlling stem cell fate, which important in cell-based regenerative medicine; however, the effect of PDA on osteogenic differentiation periodontal ligament cells (PDLSCs) not fully understood. In this study, we investigated osteoinductive PDLSCs examined how phenomenon encouraged. Methods: Osteogenic induction was established by culturing film or uncoated polystyrene...
This study compared the dentin bond strength of a new universal adhesive with that contemporary multi-step adhesives. Six experimental groups were prepared according to adhesives used and their application modes: Optibond FL (OB), Adper Single Bond Plus (SB), One-Step (OS), Clearfil SE (CS), All-Bond Universal using etch-and-rinse mode (ABE), AllBond self-etch (ABS). Micro-tensile (µTBS) failure evaluated for each group. The bonded interface was analyzed transmission electron microscopy...
Magnetism is an intriguing physical cue that can alter the behaviors of a broad range cells. Nanocomposite scaffolds exhibit magnetic properties are thus considered useful 3D matrix for culture cells and their fate control in repair regeneration processes. Here we produced nanocomposite made magnetite nanoparticles (MNPs) polycaprolactone (PCL), effects on adhesion, growth, migration odontogenic differentiation human dental pulp (HDPCs) were investigated. Furthermore, associated signaling...
Managements of exposed pulp during caries removal are major concerns dentists. Vital therapy for ex-posed is associated with the recognition prognosis preserving procedures. With advance-ments in vital therapy, successful results especially teeth irreversible pulpitis, conflict treatment guidelines based on current pulpal diagnosis system. Confusions regarding indications under system and attenuate wide spread applications therapy. Analyzing requirements improving systems guidelines, as well...
Although overexpression of the nuclear factor κB inhibitory and ubiquitin-editing enzyme A20 is thought to be involved in pathogenesis inflammatory diseases, its function periodontal disease remains unknown. The aims present study were evaluate expression patients with periodontitis effects overexpression, using a recombinant adenovirus encoding (Ad-A20), on response osteoclastic differentiation lipopolysaccharide (LPS)- nicotine-stimulated human ligament cells (hPDLCs).The concentration...
Background Recent reports suggest that thymosin beta-4 (Tβ4) is a key regulator for wound healing and anti-inflammation. However, the role of Tβ4 in osteoclast differentiation remains unclear. Purpose The purpose this study was to evaluate expression H2O2-stimulated human periodontal ligament cells (PDLCs), effects activation on inflammatory response PDLCs osteoclastic mouse bone marrow-derived macrophages (BMMs), identify underlying mechanism. Methods Reverse transcription-polymerase chain...
The aim of this study was to evaluate the combined effects mineral trioxide aggregate (MTA) and human placental extract (HPE) on cell growth, differentiation in vitro angiogenesis dental pulp cells (HDPCs) identify underlying signal transduction mechanisms. In vivo responses rats for a pulp-capping agent were examined.MTS assay. ALP activity test, alizarin red S staining RT-PCR marker genes carried out growth differentiation. HUVEC migration, mRNA expression capillary tube formation measured...
Direct pulp capping involves the placement of dental materials directly onto vital tissues after deep caries removal to stimulate regeneration reparative dentin. This physical barrier will serve as a “biological seal” between these and tissue. Although numerous direct are available, use small bioactive compounds that can potently expedite dentin formation is still underexplored. Here, authors compared evaluated pro-osteogenic pro-odontogenic effects 4 compounds— phenamil (Phen),...
This case report presents surgical endodontic management outcomes of maxillary incisors that were infected via the lateral canals. Two cases are presented in which endodontically-treated central had sustained canal infections. A treatment was performed on both teeth. Flap elevation revealed vertical bone destruction along root surface and canals, microscopy canals origin lesions. After surgically managed, teeth asymptomatic labial fistulas resolved. There no clinical or radiographic signs...
Background: Peripheral blood mononuclear cells (PBMCs) represent an attractive tissue source in pharmacogenomics and molecular immunologic studies. In order to investigate the changes biological effects, water samples were exposed a specific quantum entanglement signal from SoRegen chip for 48 hours. This study aimed evaluate immunomodulatory anti-inflammatory effects of Technology broiler layer hens PBMCs. Methods: Six-week-old Arbor Acress chickens 66-week-old Lohmann used establishment...
Abstract Background With advances in pulp preservation procedures (PPP), indications for PPP extend to exposed with symptoms teeth carious lesions. Scenario/text-based questionnaire studies report a high preference no pulpal symptoms. However, negative perceptions towards are prevalent among dentists. Identifying the differences rates and actual clinical situations is necessary determine current status of PPP. In this study, case/photo-based design was devised overcome limitations...
The occurrence of post-vital pulp therapy (VPT) symptoms is perplexing for dentists, and root canal treatment (RCT) preferred such conditions. Furthermore, managing post-VPT symptoms, rather than performing RCT, would preserve vitality enhance VPT outcomes. This study aimed to evaluate the efficacy retrials in preserving substituting RCT teeth with symptoms. was performed on exposed during caries removal symptomatic asymptomatic teeth. VPTs were repeated screened multi-time-practiced cases...
The dental follicle (DF) was harvested during the removal of an impacted third molar by oral maxillofacial surgeon. Epithelial cell isolation performed on day DF harvest. washed three times with DPBS and then dissected tissue scissors until had a pulpy or squishy consistency. Single-cell populations were pelleted centrifugation keratinocyte serum-free medium. Heterogeneous distributed in culture dish. Keratinocyte medium used to select epithelial cells. changed daily no floating debris dead...
Abstract GRHL2 is a proto-oncogene that regulates epithelial proliferation and differentiation through transcriptional regulation of large number target genes. The current study was performed to determine its role in oral carcinogenesis forkhead box 1 (FoxM1), which known oncogene for many solid tumors. expression highly elevated squamous cell carcinoma (OSCC) tissues compared with normal epithelium (NHOM), protein localized the proliferative cells at outer border invasive islands OSCC. In...
구조 강이나 터빈로터 강의 기계적 물성은 자기적 특성과 관계되므로, 비파괴적으로 특성을 측정하여 물성을 평가하는 연구가 많이 수행되었다. 따라서 자동차용 강판으로 사용되는 냉연강판에서도 측정함으로써 냉연강판의 유추할 수 있을 것이고, 냉연강판 생산 라인에서 온라인상에서 모니터할 것이다. 특성이 다른 세 종류의 CBQ 3060, 3041 및 3036의 시편을 준비하고 교류 섭동 자기장을 인가하여 특성인 가역투자율을 측정함으로서 물성인 경도와의 상관관계를 규명하였다. 시편에서 비커스 경도, 항복강도 인장강도를 측정하였다. 주파수가20 Hz일 때, surface type 프로브로 측정한 섭동자기장의 제 1차 고조파인 가역투자율의 피크 간 간격에서 구한 보자력은 비커스경도, 인장강도가 증가할 때 선형적으로 증가하였다. 주파수 20 Hz에서 lift-off에 대한 가역투자율 측정을 하였는데,lift-off가 증가함에 따라 고조파의 amplitude가 급격히 감소하였다....
The dental follicle (DF) was harvested during the removal of an impacted third molar by oral maxillofacial surgeon. Epithelial cell isolation performed on day DF harvest. washed three times with DPBS and then dissected tissue scissors until had a pulpy or squishy consistency. Single-cell populations were pelleted centrifugation keratinocyte serum-free medium. Heterogeneous distributed in culture dish. Keratinocyte medium used to select epithelial cells. changed daily no floating debris dead...