A5100446500- Bone Tissue Engineering Materials
- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Electrospun Nanofibers in Biomedical Applications
- Dental Implant Techniques and Outcomes
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Engineering Applied Research
- Plasma Applications and Diagnostics
- Aluminum Alloys Composites Properties
- 3D Printing in Biomedical Research
- Ecology and Conservation Studies
- Tissue Engineering and Regenerative Medicine
- Cellular Mechanics and Interactions
- Advanced Nanomaterials in Catalysis
- Dental Radiography and Imaging
- Periodontal Regeneration and Treatments
- Metallurgy and Material Forming
- Mesenchymal stem cell research
- Dental Erosion and Treatment
- Aluminum Alloy Microstructure Properties
- Silk-based biomaterials and applications
- Dental Research and COVID-19
- Metal Forming Simulation Techniques
- Neuroscience and Neural Engineering
Dankook University
2016-2025
Chung-Ang University
2024-2025
Cell Biotech (South Korea)
2024-2025
Korea Institute of Industrial Technology
2024
Dankook University Hospital
2024
Yonsei University
2012-2023
Seoul National University
2018-2023
Samsung (South Korea)
2008-2023
Hanjin Heavy Industries (South Korea)
2021-2023
The Royal Free Hospital
2023
Hydrogels are three-dimensional polymeric networks filled with water and mimic tissue environments. Therefore, they considered optimal to deliver cells engineer damaged tissues. The hydrogel have been significantly modified endow biochemical functionality adhesive ligands, growth factors, or degradable sites that helpful drive proper cell functions. Recently, some of the biophysical properties hydrogels emerged as key players in dictating fate. Beyond static stiffness, time-dependent...
Inducing immunogenic cell death (ICD) is a critical strategy for enhancing cancer immunotherapy. However, inefficient and risky ICD inducers along with tumor hypoxia microenvironment seriously limit the immunotherapy efficacy. Non-specific delivery also responsible this inefficiency. In work, we report drug-free bacteria-derived outer membrane vesicle (OMV)-functionalized Fe3O4-MnO2 (FMO) nanoplatform that realized neutrophil-mediated targeted photothermally enhanced system, modification of...
Tomato yellow leaf curl virus (TYLCV) is one of the most well-known tomato-infecting begomoviruses and transmitted by Bemisia tabaci. Seed transmission has previously been reported for some RNA viruses, but TYLCV not described as a seed-borne virus. In 2013 2014, without whitefly-mediated transmission, was detected in young tomato plants germinated from fallen fruits produced TYLCV-infected previous cultivation season. addition, TYLCV-Israel (TYLCV-IL) also seeds their seedlings that were...
Recapitulating the in vivo microenvironments of damaged tissues through modulation physicochemical properties scaffolds can boost endogenous regenerative capacity. A series critical events tissue healing including immune-responses, angiogenesis, and stem cell homing differentiation orchestrate to relay regeneration process. Herein, we report hierarchically structured ('microchanneled') 3D printed (named 'μCh'), contrast conventional scaffolds, induce such cellular responses a unique way that...
Although PMMA-based biomaterials are widely used in clinics, a major hurdle, namely, their poor antimicrobial (i.e., adhesion) properties, remains and can accelerate infections. In this study, carboxylated multiwalled carbon nanotubes (CNTs) were incorporated into poly(methyl methacrylate) (PMMA) to achieve drug-free adhesion properties. After characterizing the mechanical/surface anti-adhesive effects against 3 different oral microbial species (Staphylococcus aureus, Streptococcus mutans,...
Therapeutic options are quite limited in clinics for the successful repair of infected/degenerated tissues. Although prevalent treatment is complete removal whole infected tissue, this leads to a loss tissue function and serious complications. Herein dental pulp infection, as one most common problems, was selected clinically relevant case regenerate using multifunctional nanotherapeutic approach. For this, mesoporous bioactive glass nano-delivery system incorporating silicate, calcium,...
Regeneration of pathological wounds, such as diabetic ulcers, poses a significant challenge in clinical settings, despite the widespread use drugs. To overcome side effects and complications, drug-free therapeutics need to be developed promote angiogenesis while overcoming inflammation restore regenerative events. This study presents novel bioactive nanozyme based on cobalt-doped nanoglass (namely, CoNZ), which exhibits high enzymatic/catalytic activity releasing therapeutic ions. Cobalt...
Abstract Pathological dermal scars such as keloids present significant clinical challenges lacking effective treatment options. Given the distinctive feature of highly stiffened scar tissues, deciphering how matrix mechanics regulate pathological progression can inform new therapeutic strategies. Here, it is shown that keloid fibroblasts display unique metamorphoses to matrix. Compared normal fibroblasts, show high sensitivity stiffness rather than biochemical stimulation, activating...
Mesoporous bioactive nanoparticles (MBNs) have been developed as promising additives to various types of bone or dentin regenerative material. However, biofunctionality MBNs additive dental materials rarely studied. We investigated the uptake efficiency MBNs-NH2 with their endocytosis pathway and role in odontogenic differentiation clarify inherent biofunctionality. were fabricated by sol-gel synthesis, 3% APTES was used aminate these (MBNs-NH2) reverse charge from negative positive. To...