- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Optical Coherence Tomography Applications
- Organ Transplantation Techniques and Outcomes
- Gallbladder and Bile Duct Disorders
- Genetic and Kidney Cyst Diseases
- Cancer, Lipids, and Metabolism
- Gastric Cancer Management and Outcomes
- Endoplasmic Reticulum Stress and Disease
- Colorectal Cancer Screening and Detection
- Advanced Fluorescence Microscopy Techniques
- Ovarian cancer diagnosis and treatment
- Photoacoustic and Ultrasonic Imaging
- Colorectal Cancer Surgical Treatments
- Hepatitis B Virus Studies
- Color Science and Applications
Seoul National University Hospital
2003-2025
National University College
2025
New Generation University College
2025
Sungkyunkwan University
2015-2024
Samsung Medical Center
2015-2024
Konyang University
2021-2024
Samsung (South Korea)
2010-2023
Tokyo Women's Medical University
2021-2023
Inje University Haeundae Paik Hospital
2023
Kyung Hee University
2023
Objective: We compared surgical resection (SR) and radiofrequency ablation (RFA) as first-line treatment in patients with hepatocellular carcinoma (HCC) based on the risk of microvascular invasion (MVI). Background: The best curative modality between SR RFA HCC MVI remains unclear. Methods: Data from 2 academic cancer center-based cohorts a single, small (≤3 cm) who underwent were used to derive (n = 276) validate 101) prediction models for using clinical imaging variables. model was...
There is currently no consensus regarding preferred clinical outcome measures following image-guided tumor ablation or clear definitions of oncologic end points. This document proposes standardized for a broad range with recommendations on how to uniformly document, analyze, and report outcomes. The initiative was coordinated by the Society Interventional Oncology in collaboration Definition Assessment Time-to-Event End Points Cancer Trials, DATECAN, group. According predefined criteria,...
To determine if the combination of gadoxetic acid-enhanced magnetic resonance (MR) imaging and diffusion-weighted (DW) helps to increase accuracy sensitivity in diagnosis small hepatocellular carcinomas (HCCs) compared with those achieved by using each MR technique alone.The institutional review board approved this retrospective study waived requirement for informed consent. The included 130 patients (95 men, 35 women) 179 surgically confirmed HCCs (≤2.0 cm) cirrhosis (90 40 without HCC who...
The purpose of this study was to compare the performance MRI combined with MR cholangiopancreatography (MRCP) that MDCT direct cholangiography in evaluation tumor extent and resectability bile duct cancer surgical pathologic findings as reference standard.From January 2003 March 2006, 27 patients (18 men, nine women; mean age, 60.8 years; range, 43-80 years) surgically proven hilar cholangiocarcinoma or common (CBD) who had undergone preoperative 2D 3D MRCP gadolinium-enhanced triple-phase...
Purpose To compare radiofrequency (RF) ablation with nonanatomic resection (NAR) as first-line treatment in patients a single Barcelona Clinic Liver Cancer (BCLC) stage 0 or A hepatocellular carcinoma (HCC) and to evaluate the long-term outcomes of both therapies. Materials Methods This retrospective study was approved by institutional review board. The requirement for informed consent waived. Data were reviewed from 580 HCCs measuring 3 cm smaller (BCLC A) who underwent ultrasonographically...
To evaluate the frequency, risk factors, and clinical significance of aggressive intrasegmental recurrence (AIR) found after radiofrequency (RF) ablation for hepatocellular carcinoma (HCC).Institutional review board approval was obtained this retrospective study. Between March 2005 December 2010, 539 patients (414 men, 125 women; mean age, 57.91 years; age range, 30-82 years) underwent ultrasonography-guided percutaneous RF as a first-line treatment single HCC classified Barcelona Clinic...
The purpose of this study was to determine whether fusion imaging-guided percutaneous radiofrequency ablation (RFA) is effective in the management hepatocellular carcinoma (HCC) that has poor conspicuity at conventional sonography.Percutaneous RFA HCC with performed under imaging guidance. time needed for image between ultrasound and CT or MR images recorded. quality degree operator confidence identifying index tumor were graded on 4-point scales. Technical success procedure-related...
Purpose To compare the long-term therapeutic outcomes of radiofrequency (RF) ablation for hepatocellular carcinoma (HCC) in subcapsular versus nonsubcapsular locations by using propensity score matching. Materials and Methods RF HCC is controversial because a high risk incomplete or major complications. This retrospective study was approved institutional review board, requirement informed consent waived. Between April 2006 December 2011, 508 consecutive patients (396 men, 112 women; age...
In a long-term (10-year) study of radiofrequency ablation (RFA) hepatocellular carcinoma (HCC) as bridging therapy in patients listed for orthotopic liver transplantation (LT), we evaluated the impact RFA on waiting list dropout rate, post-LT tumor recurrence, and intention-to-treat, disease-specific survival (DSS). From March 2004 to October 2014, was performed initial stand-alone bridge LT 121 (men/women ratio, 83:38; mean age, 60.0 years) with 156 de novo HCCs (mean size, 2.4 cm)....
Background Accurate identification of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) before treatment is critical for selecting a proper strategy. Purpose To evaluate the interobserver agreement and diagnostic performance MRI assessment MVI HCC according to level radiologist experience. Materials Methods This retrospective study included 100 patients with surgically confirmed HCCs smaller than 5 cm who underwent gadoxetic acid–enhanced between 2013 2016. Eight postfellowship...
Given the complexity of managing hepatocellular carcinoma (HCC), a multidisciplinary approach (MDT) is recommended to optimize management HCC patients. However, evidence suggesting that MDT improves patient outcome limited.We performed retrospective cohort study all patients newly-diagnosed with between 2005 and 2013 (n = 6,619). The overall survival (OS) rates who were not managed via compared in entire 6,619), exactly matched 1,396).In cohort, 5-year rate was significantly higher (71.2%...
The first edition of the guidelines for use ultrasound contrast agents was published in 2004, dealing with liver applications. second 2008 reflected changes available and updated liver, as well implementing some nonliver third contrast-enhanced (CEUS) joint World Federation Ultrasound Medicine Biology-European Societies Biology (WFUMB-EFSUMB) venture conjunction other regional US societies such Asian Biology, resulting a simultaneous duplicate on CEUS official journals both WFUMB EFSUMB...
Background Recently introduced no-touch radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) has the potential to improve local tumor control. Purpose To evaluate midterm clinical outcomes monopolar RFA in single HCCs 2.5 cm or smaller. Materials and Methods In this multicenter trial (ClinicalTrials.gov: NCT03375281), participants were evaluated for eligibility from November 2017 January 2019. Patients with smaller planning be treated enrolled. The rate successful RFA, defined as...
The Liver Imaging Reporting and Data System (LI-RADS) offers a standardized approach for imaging hepatocellular carcinoma. However, the diverse styles structures of radiology reports complicate automatic data extraction. Large language models hold potential structured extraction from free-text reports. Our objective was to evaluate performance Generative Pre-trained Transformer (GPT)-4 in extracting LI-RADS features categories liver magnetic resonance (MRI)
Targeted Sonography for Small Hepatocellular Carcinoma Discovered by CT or MRI: Factors Affecting Sonographic DetectionMin Woo Lee1 2, Young Jun Kim1, Hee Sun Park1, Nam C. Yu3, Sung Il Jung1, Su Yeon Ko1 and Hae Jeong Jeon1Audio Available | Share
To evaluate the use of multidetector computed tomographic (CT) esophagography to grade esophageal varices and differentiate between at low risk those high for bleeding, with endoscopy as reference standard.This study was approved by institutional review board; all subjects gave informed consent. Ninety patients cirrhosis (65 men, 25 women; mean age, 54.8 years; range, 21-77 years) were prospectively enrolled underwent CT esophagography. Esophageal graded independently two endoscopists....
Purpose: To compare the diagnostic accuracy and sensitivity of combined gadoxetic acid-enhanced magnetic resonance imaging (MRI) diffusion-weighted (DWI) with each approach alone for detecting small hepatic metastases (≤1.5 cm). Materials Methods: Institutional review board approved this retrospective study waived informed patient consent. Eighty-six patients 179 liver underwent MRI including unenhanced DWI at 3.0 T. Three image sets images—gadoxetic acid set (early dynamic hepatocyte...
The objective of our study was to assess whether fusion imaging conventional ultrasound and liver CT or MR images can improve the conspicuity lesions feasibility percutaneous radiofrequency ablation (RFA) for treatment hepatocellular carcinomas (HCCs) not visible on ultrasound. Whether peritumoral anatomic landmarks be used placement an electrode in HCCs even after image also evaluated.Planning RFA performed using first then later during same session. visibility were assessed. We evaluated...
To compare the long-term outcomes of repeated hepatic resection and radiofrequency (RF) ablation for recurrent hepatocellular carcinoma (HCC) by using propensity score matching.This retrospective study was approved institutional review board, requirement to obtain informed consent waived. Thirty-nine patients who underwent 178 RF HCC (mean tumor size ± standard deviation, 1.8 cm 0.7) between November 1994 December 2012 were included in study. Patients ranged age from 24 85 years (mean, 54.9...