- Ultrasound and Hyperthermia Applications
- Ultrasound and Cavitation Phenomena
- Photoacoustic and Ultrasonic Imaging
- Ultrasound Imaging and Elastography
- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- Cardiovascular and exercise physiology
- Flow Measurement and Analysis
- Microfluidic and Bio-sensing Technologies
- Hemodynamic Monitoring and Therapy
- Optical Coherence Tomography Applications
- Infrared Thermography in Medicine
- 3D Printing in Biomedical Research
- Ultrasonics and Acoustic Wave Propagation
- Random lasers and scattering media
- Muscle activation and electromyography studies
- Advanced Radiotherapy Techniques
- Diabetic Foot Ulcer Assessment and Management
- Microbial Inactivation Methods
- Radiation Therapy and Dosimetry
- Advanced Optical Imaging Technologies
- Nanoplatforms for cancer theranostics
- Pickering emulsions and particle stabilization
- Electrohydrodynamics and Fluid Dynamics
- Bone Tissue Engineering Materials
Hokkaido University
2016-2025
Teikyo University
2011
Tokyo University of Pharmacy and Life Sciences
2011
Japan Broadcasting Corporation (Japan)
2011
Hokkaido University of Science
2002-2006
Toshiba (Japan)
1994
The first edition of the guidelines for use ultrasound contrast agents was published in 2004, dealing with liver applications. second 2008 reflected changes available and updated liver, as well implementing some nonliver third contrast-enhanced (CEUS) joint World Federation Ultrasound Medicine Biology-European Societies Biology (WFUMB-EFSUMB) venture conjunction other regional US societies such Asian Biology, resulting a simultaneous duplicate on CEUS official journals both WFUMB EFSUMB...
The inhomogeneity of tissue structure greatly affects the sensitivity oxygenation measurement by reflectance near-infrared spectroscopy. In this study, we investigated influence a fat layer on muscle in vivo tests and Monte Carlo simulation, propose method for correcting influence. three-dimensional model consisting epidermis, dermis, fat, layers was used. tests, examined measuring oxygen consumption forearm peak-to-peak variation periodic exercise vastus lateralis using newly developed...
It is known that Phosphatidyl choline-Phosphatidyl glycerol mixtures can be used for liposome formulations, making them less leaky than liposomes with only one lipid. We hypothesized this might also the case bubbles, which as ultrasound (US) contrast agents. Therefore, we have compared a series of mixed distearoyl phosphatidylcholine-distearoyl phosphatidylglycerol (DSPC-DPSG) bubbles and containing either DSPC or DSPG (and ethanolamine-polyethyleneglycol 2000, DSPE-PEG2k). Here, describe...
A new Schlieren method for visualizing an acoustic field of pulsed ultrasound was proposed, and a system developed to evaluate the validity proposed by focused diagnostic frequency range. conventional optical is not used in system. The uses short-pulsed laser, CCD camera with wide dynamic range, PC that processes images captured camera. In method, extraction light diffracted carried out subtraction without exposure. usefulness confirmed experiment which fields 5 MHz transducer were...
Abstract A brief review of optical techniques for visualizing ultrasound fields is given. Acousto-optic interaction discussed as a basic principle inhomogeneity in refractive index fields. Light diffraction and deflection are also important phenomena, especially visualization Three techniques, Schlieren, phase contrast, shadowgraph used reviewed with discussion the differences systems visualized field images. newly developed focused technique that achieves sensitive detection simple optics...
A high-speed in situ microscopic observation system developed for basic studies on mechanisms of sonoporation is introduced this paper. The main part the an inverted-type fluorescence microscope, and a camera 20 MHz maximum framing rate was used to visualize dynamics cavitation bubbles that causes effect. Differential interference contrast techniques were sensitive visualization cell changes during sonoporation. also equipped with optical tweezers can move microbubble several microns size by...
Antibubbles have been under investigation as potential vehicles in ultrasound-guided drug delivery. It is assumed that antibubbles can expand unhampered, but cannot contract beyond the size of their inner core. In this study, hypothesis was tested on endoskeletal and reference bubbles. These were subjected to 3-cycle pulses 1 MHz ultrasound, whilst being recorded with a high-speed camera operating at 10 million frames per second. At low acoustic amplitudes (200 kPa), bubbles oscillated...