A5101591671- Advanced Data Compression Techniques
- Image Enhancement Techniques
- Advanced Steganography and Watermarking Techniques
- Glioma Diagnosis and Treatment
- Image and Signal Denoising Methods
- Video Coding and Compression Technologies
- Chaos-based Image/Signal Encryption
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Advanced Image and Video Retrieval Techniques
- Digital Media Forensic Detection
- Congenital gastrointestinal and neural anomalies
- Meningioma and schwannoma management
- Tracheal and airway disorders
- Color Science and Applications
- Gastrointestinal Tumor Research and Treatment
- Head and Neck Surgical Oncology
- Diverticular Disease and Complications
- Airway Management and Intubation Techniques
- Advanced Vision and Imaging
- Robotics and Sensor-Based Localization
- Helicobacter pylori-related gastroenterology studies
- Cancer, Hypoxia, and Metabolism
- Appendicitis Diagnosis and Management
- Pelvic floor disorders treatments
Shionogi (Japan)
2022-2025
Keio University
1988-2025
Osaka Institute of Technology
2014-2024
Kobe Medical Center
2024
Kobe City Medical Center General Hospital
2013-2024
College of Industrial Technology
2012-2022
Tokai University
1999-2022
Sanno Medical Center
2021
National Hospital Organization Mito Medical Center
2018-2021
Hokkaido University
2010-2020
Purpose Whereas whole-brain radiotherapy (WBRT) has been the standard treatment of brain metastases (BMs), stereotactic radiosurgery (SRS) is increasingly preferred to avoid cognitive dysfunction; however, it not clearly determined whether with SRS as effective that WBRT or plus SRS. We thus assessed noninferiority salvage in patients BMs. Patients and Methods age 20 79 years old performance status scores 0 2-and 3 if caused only by neurologic deficits-and four fewer surgically resected BMs...
Abstract Current cartilage regenerative therapies are not fully effective in treating osteoarthritis of the knee (OAK). We have developed chondrocyte sheets for autologous transplantation and tested these vitro vivo preclinical studies, reported that promoted hyaline repair rat, rabbit, minipig models. However, has yet to be humans. Here, we report our combination therapy which conventional surgical treatment OAK, is followed by sheet repair. Eight patients with OAK defects categorized...
Interactions between biofilm cells of Pseudomonas aeruginosa and levofloxacin were studied. P. incubated for 6 days with Teflon sheets formed a on its surface. Against the bacteria, at an MIC determined by standard method strain was highly bactericidal whereas gentamicin, ceftazidime, ciprofloxacin showed no significant killing activity. Levofloxacin, ciprofloxacin, but not exhibited activity against nongrowing in phosphate buffer. In addition, levofloxacin, ability to penetrate agar...
This study explored the superiority of temozolomide (TMZ) + interferonβ (IFNβ) to standard TMZ as treatment for newly diagnosed glioblastoma (GBM) via randomized phase II screening design. Eligibility criteria included histologically proven GBM, with 50% tumor located in supratentorial areas, without involvement optic, olfactory nerves, and pituitary gland multiple lesions dissemination. Patients radiotherapy (RT) arm received RT (2.0 Gy/fr/day, 30 fr) (75 mg/m2, daily) followed by...
ABSTRACT A strong polychlorinated biphenyl (PCB) degrader, Rhodococcus sp. strain RHA1, has diverse biphenyl/PCB degradative genes and harbors huge linear plasmids, including pRHL1 (1,100 kb), pRHL2 (450 pRHL3 (330 kb). The are distributed mainly on the plasmids. In this study, structural functional characteristics of were determined. We constructed a physical map pRHL2, enzyme genes, bphB2, etbD2, etbC, bphDEF, bphC2 , bphC4 localized in three regions. Conjugal transfer between RHA1 mutant...
The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise endocrine and exocrine cells. A key guidance mechanism for pancreatic development has previously been found be epithelial-mesenchymal interaction. Interactions within the epithelium, however, have not well studied. Glucagon earliest peptide hormone present at appreciable levels in developing epithelium (embryonic day [E]-9.5 mouse). Insulin accumulation begins slightly later (E11 mouse), followed by...
We investigated the effect of an erythropoietin (EPO)-gelatin hydrogel drug delivery system (DDS) applied to heart on myocardial infarct (MI) size, left ventricular (LV) remodelling and function.Experiments were performed in a rabbit model MI. The size was reduced, LV function improved 14 days 2 months after MI but not at EPO-DDS group. number cluster differentiation 31(CD31)-positive microvessels expression receptor (EPO-R), phosphorylated-Akt (p-Akt), phosphorylated glycogen synthase...
An encryption scheme of JPEG images in the bitstream domain is proposed. The proposed preserves format even after encrypting images, and file size encrypted exact same as that original images. Several methods for have been However, since some marker codes are generated or lost process, bitstreams generally changed due to operations. method inputs selectively encrypts additional bit components Huffman code bitstreams. This feature allows us with data recoded image transmission when replaced...
The COVID-19 pandemic, spanning from early 2020 to late 2022, posed unprecedented challenges for global public health. However, it also spurred innovative approaches pandemic management, notably the development of pathogen detection in wastewater. It was successfully demonstrated that wastewater analysis can not only reflect ongoing infections but serve as an indicator disease prevalence within communities. Recognizing value longitudinal analyses various pathogens, we identified need...
The postoperative course of intestinal Behçet's disease was studied in nine patients who had undergone a total 15 operations due to ulcers.These were followed up for an average 6.0 years (range, 1 year, 3 months 13 years, 10 months) after each operation and they repeatedly examined by double-contrast radiography and/or colonofiberscopy.Recurrence ulcers observed 12 (80 percent) the surgical cases. incidence (50 recurrence six cases which intraoperative endoscopy revealed no abnormality...
Rhodococcus sp. strain RHA1, a potent polychlorinated-biphenyl (PCB)-degrading strain, contains three linear plasmids ranging in size from 330 to 1,100 kb. As part of genome sequencing project, we report here the complete sequence and characterization smallest least-well-characterized RHA1 plasmids, pRHL3. The plasmid is an actinomycete invertron, containing large terminal inverted repeats with tightly associated protein predicted open reading frame (ORF) that similar mycobacterial rep gene....
The tuberculum sellae meningioma (TSM) arises from the sellae, chiasmatic sulcus, and limbus sphenoidale.To retrospectively analyze patients with TSM who underwent surgery via an anterior interhemispheric approach, special attention to visual outcomes.Nine consecutive between April 2004 December 2009 were examined. Visual impairment score (VIS) was used status of patients. A VIS is sum scores in specific tables for acuity field defects. sequentially evaluated preoperative period within 2...
Even after surgery and intensive postoperative management, the mortality rate associated with colorectal perforation is high. Identification of markers using routinely available preoperative parameters important. We enrolled consecutive patients who underwent operations from January 2010 to 2015. divided them into a survivor group compared clinical characteristics between two groups. Additionally, we different etiologies: malignant versus benign diverticular nondiverticular. used χ 2...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to be present in sewage, and wastewater-based epidemiology has attracted much attention. However, the physical partitioning of SARS-CoV-2 wastewater removal efficiency treatment systems require further investigation. This study aimed investigate detectability assess its a large-scale septic tank employing anaerobic, anoxic, oxic processes sequential batch reactor, which was installed disease 2019 (COVID-19) quarantine...