A5102838938- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Hypoxia, and Metabolism
- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Radiopharmaceutical Chemistry and Applications
- Sarcoidosis and Beryllium Toxicity Research
- Head and Neck Cancer Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Thyroid Cancer Diagnosis and Treatment
- Radiation Detection and Scintillator Technologies
- Intracranial Aneurysms: Treatment and Complications
- Adrenal and Paraganglionic Tumors
- Bone and Joint Diseases
- Bone health and treatments
- Brain Metastases and Treatment
- Medical Imaging and Pathology Studies
- Epilepsy research and treatment
- Radiation Dose and Imaging
- AI in cancer detection
Fukushima Medical University
2020-2024
Hokkaido University
2013-2022
Hokkaido University Hospital
2009-2021
Fukushima Medical University Hospital
2020-2021
Daido University
2008-2020
Osaka Medical and Pharmaceutical University
2019
Omron (Japan)
1995-2015
University of Toyama
2014
Shiga University
2012
Klinikum rechts der Isar
2009
Clinical features and pathophysiology of postoperative hyperperfusion in moyamoya disease are still unclear. This study was aimed to clarify the incidence time course determine independent predictors disease.This prospective included 41 patients who underwent surgical revascularization for disease. Using (15)O-gas positron emission tomography, hemodynamic metabolic parameters were quantified before surgery. single photon computed cerebral blood flow serially measured just after surgery on 2...
Tumor hypoxia is well known to be radiation resistant. <sup>18</sup>F-fluoromisonidazole (<sup>18</sup>F-FMISO) PET has been used for noninvasive evaluation of hypoxia. Quantitative <sup>18</sup>F-FMISO uptake thus expected play an important role in the planning dose escalation radiotherapy. However, reproducibility remained unclarified. We therefore investigated tumor by using quantitative analysis uptake. <b>Methods:</b> Eleven patients with untreated head and neck cancer underwent 2...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Nov 2002Human Brain Region Response to Distention or Cold Stimulation the Bladder: A Positron Emission Tomography Study SHINOBU MATSUURA, HIDEHIRO KAKIZAKI, TAKAHIKO MITSUI, TOHRU SHIGA, NAGARA TAMAKI, and TOMOHIKO KOYANAGI MATSUURASHINOBU MATSUURA , KAKIZAKIHIDEHIRO KAKIZAKI MITSUITAKAHIKO MITSUI SHIGATOHRU SHIGA TAMAKINAGARA TAMAKI KOYANAGITOMOHIKO View All Author...
As the number of PET/CT scanners increases and FDG becomes a common imaging modality for oncology, demands automated detection systems on artificial intelligence (AI) to prevent human oversight misdiagnosis are rapidly growing. We aimed develop convolutional neural network (CNN)-based system that can classify whole-body PET as 1) benign, 2) malignant or 3) equivocal.This retrospective study investigated 3485 sequential patients with suspected disease, who underwent at our institute. All...
Patients with Parkinson's disease often have urine storage symptoms, such as urinary urgency, frequency and incontinence, which are induced by detrusor overactivity. However, little is known of the mechanisms inducing overactivity in this disease. We previously examined human brain response to bladder filling healthy male volunteers using positron emission tomography. hypothesized that activation patterns would be different patients disease.Nine were catheterized via urethra for intravesical...
Artificial neural network (ANN)-based bone scan index (BSI), a marker of the amount metastasis, has been shown to enhance diagnostic accuracy and reproducibility but is potentially affected by training databases. The aims this study were revise software using large number Japanese databases validate its compared with original Swedish database.The BSI was calculated EXINIbone (EB; EXINI Diagnostics) database (n = 789). from single institution (BONENAVI version 1, BN1, n 904) revised nine...
<b><i>Background:</i></b> Vulnerable and inflamed plaques in the carotid artery are at high risk of ischemic stroke, suggesting importance diagnostic modalities to detect them patients with stenosis sensitivity specificity. Although many investigators have reported that magnetic resonance imaging (MRI) is a useful tool predict vulnerable components plaque, its validity not established. On other hand, <sup>18</sup>F-fluorodeoxyglucose (FDG) positron...
To investigate the clinical features of patients with neuroendocrine tumors (NETs) who could not complete standard protocol (4 cycles 7.4 GBq per 8 weeks) 177Lu-DOTATATE treatment. A retrospective single-center analysis was conducted on 26 underwent treatment between December 2021 and August 2024. Therapeutic outcome compared features, including location number metastatic lesions, interval from diagnosis to first treatment, laboratory data. Statistical analyses were performed identify...
It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide comparable elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, this study, the authors aimed clarify whether OEF all reduced cerebral blood flow (CBF) and CVR (type 3) single photon computed (SPECT), and, if not, specify underlying pathophysiology of type 3 but normal OEF.This study included 46 who had decreased CBF...
Hypoxia is a common feature of cancer and prognostic factor for many types cancer. (18)F-fluoromisonidazole ((18)F-FMISO) PET can detect tumor hypoxia noninvasively. Hypoxia-inducible factor-1 (HIF-1) key player in the transcriptional response to low oxygen tension Its activity mainly dependent on stability modification HIF-1α, which composition HIF-1. However, it unclear whether (18)F-FMISO identify HIF-1α expression oral squamous cell carcinoma (OSCC). The present study was performed...
Effective treatments for malignant neuroendocrine tumors are under development. While iodine-131 metaiodobenzylguanidine (131I-MIBG) radiotherapy has been used in the treatment of tumors, there few studies evaluating its therapeutic effects and safety a multicenter cohort. In current study, we sought to evaluate 131I-MIBG therapy conditions including pheochromocytoma paraganglioma within Forty-eight (37 11 paraganglioma) from four centers underwent clinical radiotherapy. The tumor responses...
The aim of this study was to determine whether deep convolutional neural network (DCNN)-based features can represent the difference between cardiac sarcoidosis (CS) and non-CS using polar maps. A total 85 patients (33 CS 52 patients) were analyzed as our subjects. One radiologist reviewed PET/CT images defined left ventricle region for construction We extracted high-level from maps through Inception-v3 evaluated their effectiveness by applying them a classification task. Then we introduced...
Objective It has recently been reported that 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for estimation of the chemotherapy effect. Thus, we examined value FDG-PET in assessing efficacy advanced pancreatic cancer, and compared this modality with tumor markers (TMs) CT. Patients Methods Nineteen patients unresectable adenocarcinoma were enrolled. All received gemcitabine S-1, an oral derivative 5-fluorouracil, underwent FDG-PET, CT, serological examination TMs...